Ординатура / Офтальмология / Английские материалы / Handbook of Optical Coherence Tomography_Bouma, Tearney_2002

To our wives, families, and all of our colleagues, especially the contributors, who have dedicated many hours to writing and editing chapters for this book

ISBN: 0-8247-0558-0

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Preface

Optical coherence tomography (OCT) is a recently developed imaging technology that has stimulated considerable interest in the fields of medicine, biology, and material science. The unique capability of OCT to noninvasively explore microstructure within turbid media using nonionizing radiation has opened the door to applications such as optical biopsy, surgical guidance, studies of developmental biology, and quality control of advanced composites in situ.

The technological innovations that have led to the current success of OCT are manifold and have been published in the scientific literature of optical communications, optical engineering, applied physics, and biomedical engineering. Similarly, the applications of OCT have been separately described in the publications of the relevant fields. The diversity of these publications has led to a need for a comprehensive handbook describing OCT and detailing the advances. The aim of this book, then, is to address this need and to serve as a repository for engineers and scientists involved with the development of OCT technology. Sufficient detail is given to enable newcomers to the field to construct a state-of-the-art OCT imaging system. In addition, the book will serve as a reference for medical clinicians wishing to understand the fundamentals of OCT and its capabilities and limitations.

Chapter 1 presents historical background describing the development of OCT and includes citations to the primary literature. The following five chapters provide a summary of the technology specific to each of the major subcomponents of a typical OCT system, including optical sources, fiber optics, temporal delay scanning, OCT probe design, detection, and system integration. Chapters 7 through 13 are devoted to new imaging concepts spawned from OCT research, such as the reduction of speckle in OCT images, polarization-sensitive OCT, the detection of Doppler-shifted backreflection to determine flow, the combined use of OCT and confocal microscopy, spectral radar, and alternative imaging geometries for OCT.

The applications section (Chapters 14 to 28) begins with a summary of the use of OCT for measuring optical properties and a discussion of nonbiological applications of OCT such as monitoring advanced composites and optical data storage. Biological and medical applications are grouped by topic, beginning with developmental biology and continuing through the major human tissue systems that have

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Contents

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Contributors

P. Andretzky University of Erlangen-Nuernberg, Erlangen, Germany

H. T. Aretz Harvard Medical School and Wellman Laboratories of Photomedicine, Massachusetts General Hospital, Boston, Massachusetts

E. Beaurepaire CNRS, ESPCI, Paris, France

Reginald Birngruber Medical Laser Center Lu¨beck, Lu¨beck, Germany

T. J. Brady Harvard Medical School and Wellman Laboratories of Photomedicine, Massachusetts General Hospital, Boston, Massachusetts

Stephan Brand Harvard Medical School and Wellman Laboratories of Photomedicine, Massachusetts General Hospital, Boston, Massachusetts

Mark E. Brezinski Harvard Medical School, Massachusetts General Hospital, Boston, Massachusetts

A. C. Boccara CNRS, ESPCI, Paris, France

Stephen A. Boppart Massachusetts Institute of Technology, Cambridge,

Massachusetts

Brett E. Bouma Harvard Medical School and Wellman Laboratories of Photomedicine, Massachusetts General Hospital, Boston, Massachusetts

Zhongping Chen University of California at Irvine, Irvine, California

Stephen R. Chinn* Lincoln Laboratory, Massachusetts Institute of Technology, Lexington, Massachusetts

Bill W. Colston, Jr. Lawrence Livermore National Laboratory, Livermore,

California

Current affiliation: Malachite Technologies, Methuen, Massachusetts

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Manish D. Kulkarni Zeiss Humphrey Systems, Dublin, California

Eva Lankenau Medical Laser Center Lu¨beck, Lu¨beck, Germany

M. Lebec CNRS, CPE, Universite´ Claude Bernard, Villeurbanne, France

T. Lindmo Norwegian University of Science and Technology, Trondheim, Norway

M. W. Lindner University of Erlangen-Nuernberg, Erlangen, Germany

Thomas E. Milner University of Texas at Austin, Austin, Texas

J. Stuart Nelson University of California at Irvine, Irvine, California

Norman S. Nishioka Harvard Medical School and Wellman Laboratories of Photomedicine, Massachusetts General Hospital, Boston, Massachusetts

Joachim Noack Medical Laser Center Lu¨beck, Lu¨beck, Germany

Constantinos Pitris Massachusetts Institute of Technology, Cambridge,

Massachusetts

Carmen A. Puliafito University of Miami School of Medicine, Miami, Florida

Rebecca Richards-Kortum The University of Texas at Austin, Austin, Texas

Mark J. Rivellese Tufts University School of Medicine, Boston, Massachusetts

Andrew M. Rollins Case Western Reserve University, Cleveland, Ohio

H. Saint-Jalmes Universite´ Claude Bernard-Lyon I, Villeurbanne, France

Ujwal S. Sathyam Lawrence Livermore National Laboratory, Livermore, California

K. Schlendorf Harvard Medical School and Wellman Laboratories of Photomedicine, Massachusetts General Hospital, Boston, Massachusetts

J. M. Schmitt Hong Kong University of Science and Technology, Hong Kong, People’s Republic of China

A.M. Sergeev Institute of Applied Physics, Nizhny Novgorod, Russia

A.V. Shakhov Nizhny Novgorod Medical Academy, Nizhny Novgorod, Russia

N. M. Shakhova Nizhny Novgorod Medical Academy, Nizhny Novgorod, Russia

M. S. Shishkov Harvard Medical School and Wellman Laboratories of Photomedicine, Massachusetts General Hospital, Boston, Massachusetts

Shyam M. Srinivas University of California at Irvine, Irvine, California

Eric A. Swanson* Coherent Diagnostic Technology, Concord, Massachusetts

Guillermo J. Tearney Harvard Medical School and Wellman Laboratories of Photomedicine, Massachusetts General Hospital, Boston, Massachusetts

Rujchai Ung-Arunyawee Case Western Reserve University, Cleveland, Ohio

Current affiliation: Sycamore Networks, Chelmsford, Massachusetts