- •CONTENTS
- •PREFACE
- •Ocular discharge
- •Eyelid margin inflammation
- •Inflammatory mass
- •Noninflammatory mass
- •Eyelid malpositions
- •Conjunctival lesions
- •Vascular tumors
- •References
- •2 MALIGNANT TUMORS
- •Introduction
- •Basal cell carcinoma
- •Basal cell nevus syndrome
- •Squamous cell carcinoma
- •Keratoacanthoma
- •Adenocanthoma
- •Sebaceous gland carcinoma
- •Lymphoma
- •Malignant melanoma
- •Sweat gland carcinoma
- •Merkel cell tumor
- •Rhabdomyosarcoma
- •Metastatic eyelid carcinoma
- •References
- •Pigmented lesions
- •Inflammations
- •Discoid lupus
- •Benign cystic lesions
- •Benign epithelial tumors
- •Precancerous epithelial tumors
- •Adnexal tumors
- •Xanthelasma
- •Amyloidosis
- •Neurofibromatosis (von Recklinghausen’s disease)
- •References
- •Basal cell carcinoma
- •Sebaceous carcinoma
- •Squamous cell carcinoma
- •Premalignant eyelid lesions
- •Merkel cell tumor
- •Metastatic eyelid carcinoma
- •Melanocytic tumors
- •References
- •Biopsy techniques
- •Treatment
- •References
- •Skin
- •Muscles
- •Tarsal plates
- •Orbital septum
- •Orbital fat
- •Conjunctiva
- •Vascular supply
- •Lymphatic drainage
- •Nerves of the eyelids
- •Lacrimal drainage system
- •References
- •General principles
- •Principles of radiosurgery
- •References
- •Small central lid margin defects
- •Small lateral or medial lid margin defects
- •Medium lower lid defects extending to the medial canthal angle
- •Medium defects extending beyond the medial canthal angle
- •References
- •Small upper lid margin defects
- •References
- •General considerations
- •Primary closure
- •Advancement flaps
- •Full-thickness skin grafts
- •References
- •Medial canthal defects
- •Lateral canthal defects
- •References
- •INDEX
Eyelid Tumors
Clinical Diagnosis and
Surgical Treatment
Second Edition
Jay Justin Older MD, FACS
Affiliate Professor of Ophthalmology
University of South Florida
College of Medicine
Tampa, Florida, USA
With a contribution from
Richard J Grostern MD
Assistant Professor of Ophthalmology and Pathology
Rush Medical College of Rush University
Chicago, Illinois, USA
MANSON
PUBLISHING
Dedication
To my wife, Lois, and my children, Jessica and Benjamin, for their continued love and support.
Acknowledgements
This textbook is the product of my experience and knowledge, which, in great measure, is derived from those who taught and encouraged me. My parents, Dr. Lester Older and Gertrude Older encouraged me to study medicine. My mother deserves special recognition for reviewing the manuscript for the first edition. My brother, Dr. Robert Older, assisted me with many computer related topics.
Four men were instrumental in shaping my medical career. In Stanford Medical School, I benefited from the guidance of Dr. Lowell Rantz and Dr. Kenneth Vosti. During my fellowship year at the University of California in San Francisco, Dr. Crowell Beard and Dr. Marvin Quickert instilled in me the values and skills that would carry me through a career in oculoplastic surgery.
Photography for the second edition was done by my office assistants, Ms. Lori Gilmore, Ms. Lisa McLeod, Ms. Sue Ramsey and Ms. Wendy Shuford. Ms. Susan Commee deserves credit for assistance with the manuscript review and references.
I would like to thank Mr. Michael Manson, the publisher, for giving me the opportunity to write a second edition of this text. Ms. Jill Northcott was very helpful in the early phases of preparation. Mr. Paul Bennett, Ms. Clair Chaventré and Ms. Ruth Maxwell assisted me with all phases of the manuscript. Ms. Susan Tyler of Cactus Design and Illustration did an excellent job of creating accurate and representative drawings of the surgical procedures.
Copyright © 2003 Manson Publishing Ltd
ISBN: 1–84076–029–X
All rights reserved. No part of this publication may be reproduced, stored in a retrieval system or transmitted in any form or by any means without the written permission of the copyright holder or in accordance with the provisions of the Copyright Act 1956 (as amended), or under the terms of any licence permitting limited copying issued by the Copyright Licensing Agency, 33–34 Alfred Place, London WC1E 7DP, UK.
Any person who does any unauthorized act in relation to this publication may be liable to criminal prosecution and civil claims for damages.
A CIP catalogue record for this book is available from the British Library.
For full details of all Manson Publishing Ltd titles please write to:
Manson Publishing Ltd, 73 Corringham Road, London NW11 7DL, UK.
Tel: +44(0)20 8905 5150
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Email: manson@man-pub.demon.co.uk
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Commissioning editor: Jill Northcott
Project manager: Paul Bennett
Printed in Spain
Contents
PREFACE |
6 3 BENIGN TUMORS AND RELATED |
|
||
|
|
CONDITIONS |
38 |
|
SECTION 1: DIAGNOSIS |
|
Pigmented lesions |
38 |
|
AND MANAGEMENT |
7 |
Freckle (ephelis) |
38 |
|
|
|
Lentigo |
38 |
|
1 DIFFERENTIAL DIAGNOSIS OF |
|
Lentigo maligna (melanotic freckle of |
|
|
EYELID TUMORS |
7 |
Hutchinson) |
38 |
|
Ocular discharge |
7 |
Nevus |
38 |
|
Eyelid margin inflammation |
7 |
Junctional nevus |
38 |
|
Inflammatory mass |
8 |
Intradermal nevus |
38 |
|
Noninflammatory mass |
9 |
Compound nevus |
38 |
|
Eyelid malpositions |
12 |
Blue nevus |
40 |
|
Conjunctival lesions |
12 |
Congenital oculodermal melanocytosis |
|
|
Vascular tumors |
12 |
(nevus of Ota) |
40 |
|
Race and eyelid tumors |
12 |
Treatment |
40 |
|
References |
13 |
Inflammations |
40 |
|
2 MALIGNANT TUMORS |
14 |
Blepharitis |
40 |
|
Seborrheic blepharitis |
40 |
|||
Introduction |
14 |
Staphylococcal blepharitis |
40 |
|
Basal cell carcinoma |
14 |
|||
Treatment |
40 |
|||
Treatment |
18 |
|||
Comment |
40 |
|||
Comment |
18 |
|||
Hordeolum |
41 |
|||
Basal cell nevus syndrome |
20 |
|||
External hordeolum |
41 |
|||
Squamous cell carcinoma |
20 |
|||
Internal hordeolum |
41 |
|||
Keratoacanthoma |
25 |
|||
Treatment |
41 |
|||
Adenocanthoma |
25 |
|||
Chalazion |
42 |
|||
Treatment |
25 |
|||
Treatment |
42 |
|||
Comment |
25 |
|||
Comment |
42 |
|||
Sebaceous gland carcinoma |
26 |
|||
Viral inflammations |
42 |
|||
Treatment |
28 |
|||
Molluscum contagiosum |
42 |
|||
Lymphoma |
28 |
|||
Verruca (wart) |
42 |
|||
Treatment |
28 |
|||
Other inflammations |
42 |
|||
Comment |
28 |
|||
Discoid lupus |
43 |
|||
Malignant melanoma |
30 |
|||
Benign cystic lesions |
44 |
|||
Treatment |
30 |
|||
Sudoriferous cysts |
44 |
|||
Comment |
30 |
|||
Sebaceous cysts |
44 |
|||
Malignant melanoma of the conjunctiva |
32 |
|||
Epidermal inclusion cysts |
44 |
|||
Sweat gland carcinoma |
32 |
|||
Epidermoid cysts |
46 |
|||
Merkel cell tumor |
32 |
|||
Dermoid cysts |
46 |
|||
Rhabdomyosarcoma |
34 |
|||
Treatment |
46 |
|||
Metastatic eyelid carcinoma |
34 |
|||
Comedo (blackhead) |
46 |
|||
References |
35 |
|||
|
|
|||
3 BENIGN TUMORS AND RELATED CONDITIONS (continued)
Benign epithelial tumors Papilloma
Seborrheic keratosis (basal cell papilloma, seborrheic wart, senile verruca)
Inverted follicular keratosis (basosquamous cell epidermal tumor, basosquamous cell acanthoma, irritated seborrheic keratosis)
Precancerous epithelial tumors Actinic keratosis (solar keratosis) Dysplasia
Adnexal tumors Sebaceous gland tumors
Congenital sebaceous gland hyperplasia (nevus sebaceous Jadassohn, congenital sebaceous gland hamartoma)
Sebaceous adenoma Tumors of hair follicles
Trichoepithelioma
Calcifying epithelioma of Malherbe (pilomatrixoma)
Trichofolliculoma and trichilemmoma Sweat gland tumors
Syringoma
Eccrine spiradenoma (nodular hidradenoma, clear cell hidradenoma, clear cell myoepithelioma)
Syringocystadenoma papilliferum Xanthelasma
Treatment Amyloidosis
Necrobiotic xanthogranuloma Neurofibromatosis (von Recklinghausen’s
disease) Treatment
References
|
5 TREATMENT OF EYELID TUMORS |
61 |
|
|
Biopsy techniques |
61 |
|
47 |
Treatment |
62 |
|
47 |
Surgery |
62 |
|
|
Mohs technique |
62 |
|
48 |
Frozen section control |
62 |
|
|
Radiation therapy |
63 |
|
|
Cryotherapy |
63 |
|
48 |
Comment |
63 |
|
49 |
References |
64 |
|
49 |
|
|
|
49 |
SECTION 2: RECONSTRUCTION |
|
|
50 |
|
||
50 |
OF THE EYELIDS |
65 |
|
50 |
6 SURGICAL ANATOMY |
65 |
|
Skin |
65 |
||
50 |
|||
Muscles |
66 |
||
50 |
|||
Orbicularis oculi |
66 |
||
50 |
|||
Levator palpebrae superioris |
66 |
||
|
|||
50 |
Capsulopalpebral fascia |
66 |
|
Müller’s muscles |
67 |
||
50 |
|||
Tarsal plates |
68 |
||
50 |
|||
Comment |
68 |
||
50 |
|||
Orbital septum |
68 |
||
|
|||
|
Orbital fat |
68 |
|
50 |
Conjunctiva |
69 |
|
Comment |
69 |
||
50 |
|||
Vascular supply |
69 |
||
52 |
|||
Arteries |
69 |
||
52 |
|||
Veins |
70 |
||
52 |
|||
Lymphatic drainage |
70 |
||
52 |
|||
Comment |
70 |
||
|
|||
52 |
Nerves of the eyelids |
70 |
|
Comment |
70 |
||
52 |
|||
Lacrimal drainage system |
71 |
||
54 |
|||
References |
71 |
||
|
4 HISTOPATHOLOGY OF EYELID TUMORS |
55 |
Richard J Grostern |
|
Basal cell carcinoma |
55 |
Sebaceous carcinoma |
56 |
Squamous cell carcinoma |
56 |
Premalignant eyelid lesions |
58 |
Actinic keratosis |
58 |
Bowen’s disease |
58 |
Radiation dermatosis |
58 |
Merkel cell tumor |
58 |
Metastatic eyelid carcinoma |
58 |
Melanocytic tumors |
58 |
Melanocytic nevus |
58 |
Malignant melanoma |
60 |
References |
60 |
7 GENERAL PRINCIPLES OF EYELID |
|
RECONSTRUCTION AND RADIOSURGERY |
72 |
General principles |
72 |
Principles of radiosurgery |
72 |
Technique |
73 |
Skin incisions |
74 |
Soft tissue dissection |
74 |
Flaps |
74 |
Grafts |
74 |
Anesthesia |
77 |
References |
77 |
8 LOWER EYELID RECONSTRUCTION
Small central lid margin defects
Small lateral or medial lid margin defects Defects which extend medial to the punctum Medium lower lid defects extending to the
medial canthal angle
Medium to large lower lid defects Medium defects extending beyond the
medial canthal angle
Medium-sized defects in the lateral aspect of the lower lid
Medium to large lower lid defects Modifications
Alternative method for lateral lower lid defect
Alternative method for medial or central lower lid medium defect
Second stage Hughes procedure References
9 UPPER EYELID RECONSTRUCTION
78 11 RECONSTRUCTION OF THE MEDIAL |
|
|
78 |
AND LATERAL CANTHI |
113 |
79 |
Medial canthal defects |
113 |
80 |
General considerations |
113 |
|
Spontaneous granulation |
113 |
80 |
Full-thickness skin grafts |
116 |
80 |
Advancement and rotation flaps |
117 |
|
Advancement flap |
117 |
84 |
Myocutaneous island flap |
118 |
|
‘V’ to ‘Y’ rotation flap |
118 |
86 |
Midline forehead flap |
120 |
90 |
Cheek rotation flap |
120 |
95 |
Lateral canthal defects |
122 |
|
General considerations |
122 |
95 |
Periosteal flaps |
122 |
|
References |
125 |
96 |
INDEX |
126 |
96 |
||
96 |
|
|
97 |
|
|
Small upper lid margin defects |
97 |
Medium-sized upper lid margin defects |
98 |
Lateral advancement flap |
98 |
Modified tarsoconjunctival flap |
99 |
Large defects in the upper eyelid |
102 |
References |
106 |
10 REPAIR OF DEFECTS NOT INVOLVING |
|
EYELID MARGINS |
107 |
General considerations |
107 |
Primary closure |
107 |
Advancement flaps |
108 |
Full-thickness skin grafts |
112 |
References |
112 |
6
Preface
Eyelid Tumors was written to help the physician diagnose eyelid tumors in the clinical setting and to assist the surgeon who might wish to remove the tumors and repair the eyelid defects. One of the reasons to write the book was that I had seen many patients in my oculoplastic practice with a history of late diagnoses of malignant eyelid tumors. Early diagnosis of eyelid malignancies would lead to better patient care, in the majority of cases. The other reason for writing the text was to share my surgical experiences with other surgeons. Many of the texts in print at the time I wrote the first edition listed a variety of repairs for a specific condition. I, however, chose to discuss only those techniques that gave me the best results. The first section contained many pictures of different lesions with descriptions and anecdotal information. It was my belief that the clinician would look at the book as help in diagnosing the eyelid lesion. By comparing the patient’s lesion with the photos in the book, the physician would be in a better position to make a differential diagnosis and continue with the patient’s care. The care might require further testing, a referral, or definitive treatment.
The first edition was sold out and was not reprinted. Newer techniques of surgical repair were developed since that edition was published. My experience with eyelid tumors increased during the next 15 years and I continue to see patients who present with late diagnoses of eyelid malignancies. My research indicated that eyelid tumors are relatively common in most parts of the world. It is my hope that an expanded second edition will be accepted by an
international audience and result in better medical care for those patients who present with eyelid tumors.
The second edition is divided into two parts. The first deals with the diagnosis of eyelid tumors. Chapter 1 emphasizes the difficulty in the differential diagnosis of malignant tumors because different conditions look similar and the same type of tumor may have a variety of presentations. The next two chapters deal with the presentation and performance of benign and malignant eyelid tumors. By including more than 150 photographs, I intend to show the reader the wide variety of eyelid tumor presentations. Chapter 4 includes the microscopic pathology of malignant eyelid tumors, a subject not included in the first edition. It is written by Dr. Richard Grostern, an ophthalmic pathologist.
The second part of the text discusses the surgical treatment of eyelid tumors and eyelid repair. A new addition to the second edition is the discussion of radiosurgery. This is important in understanding the surgical repair techniques since radiosurgery is my main method of soft tissue dissection. This second part includes newer techniques of eyelid repair. Although there are many methods for repair of eyelid defects, I included only those procedures which I have used and found to be most effective. It is my belief that clinical photos of surgery combined with explicit drawings of these techniques will aid the reader in performing eyelid tumor surgery.
Jay Justin Older
Jay Justin Older, MD, FACS
Dr. Older graduated from Rutgers University, New Jersey. He then completed his medical and ophthalmology training at Stanford University, California. After finishing his residency in ophthalmology, Dr. Older completed a fellowship in oculoplastic surgery at the University of California in San Francisco.
Dr. Older is board certified in ophthalmology and is a fellow of the American Academy of Ophthalmology from which he has received both the Honor Award and the Senior Honor Award for distinguished service in the field of education. He is past President of the American Society of Ophthalmic Plastic and Reconstructive Surgery, and he has also lectured extensively on the subject of eyelid surgery in America, Europe, and Asia.
