- •Contents
- •Dedication
- •About the Authors
- •Preface
- •Acknowledgments
- •CASE NO. 1A
- •Discussion
- •CASE NO. 1B
- •REFERENCES
- •CASE NO. 2A
- •Discussion
- •CASE NO. 2B
- •REFERENCES
- •CASE NO. 3A
- •Discussion
- •CASE NO. 3B
- •Discussion
- •REFERENCES
- •CASE NO. 4
- •Discussion
- •REFERENCES
- •CASE NO. 5
- •Discussion
- •REFERENCES
- •CASE NO. 6
- •Discussion
- •REFERENCES
- •CASE NO. 7
- •Discussion
- •REFERENCES
- •CASE NO. 8A
- •Discussion
- •CASE NO. 8B
- •REFERENCES
- •CASE NO. 9
- •Discussion
- •REFERENCES
- •CASE NO. 10
- •Discussion
- •REFERENCES
- •CASE NO. 11
- •REFERENCES
- •CASE NO. 12
- •REFERENCES
- •CASE NO. 13
- •REFERENCES
- •CASE NO. 14
- •REFERENCES
- •CASE NO. 15
- •REFERENCES
- •CASE NO. 16
- •REFERENCES
- •CASE NO. 17
- •Discussion
- •REFERENCES
- •CASE NO. 18
- •Exam
- •Index
Index
A
abducens nerve, 53, 164 abscesses, 45–49 acalculia, 44 acetazolamide, 32, 39, 42 acetominophen, 33
activated protein C resistance, 28 Addison’s disease, 29
Adie tonic pupil, 122–124 age of patients
carotid-cavernous sinus fistulae and, 3
leukemia and, 109 ODEMS and, 128, 129 optic neuritis and, 65–68
tissue plasminogen activator (tPA) treatment and, 16
vasculopathic risk factors, 84, 134
agnosia, finger, 44
alcohol consumption, 115, 117 alexia, 44
all-trans-retinoic acid (ATRA), 29
amaurosis fugax, 133–142 anemia, 113
aneurysms
central nervous system impairment, 45
cranial nerve palsies and, 55, 56, 80, 82–87
giant basilar artery tip, 61 internal carotid artery, 6, 89 intracavernous carotid, 5, 6, 55,
82, 159
middle cerebral artery (MCA), 91, 92, 94
ophthalmic artery, 69, 74 posterior communicating artery,
86, 89, 91, 92, 94 signs and symptoms, 123 suprasellar, 147
angioplasty, 19, 29
anisocoria, 9, 21, 81, 115, 117, 121–125, 155–162
anorexia, 117 anosognosia, 44
Page numbers in bold type indicate figures.
169
Emergencies in Neuro-Ophthalmology: A Case Based Approach
anterior chamber, 1, 139 antibiotics, 130 anticoagulants, 17, 29, 158 antiphospholipid antibody
syndrome, 28
antiplatelet therapy, 23, 158, 162 antithrombin III deficiency, 28 aortic vascular disease, 138 aphasia, 44, 134
applanation tonometry, 4, 11 apraclonidine test, topical,
157–159 apraxia, 44
arteriovenous malformations (AVM), 26, 29
aspirin, 145, 146, 162 ataxia, 54, 109, 116, 117 atrial fibrillation, 19 atropine, 124 autotopagnosia, 44
B
bacteria, abscess-causing, 45, 46 Balint syndrome, 61
balloons, detachable, 7 barbiturates, 61
bariatric surgery, 115, 116. See also obesity
Bartter’s syndrome, 29 basilar artery, 61, 62
behavioral changes, 59, 61. See also mental status changes
Behçet disease, 28, 29 Bell’s phenomenon, 59 Bickerstaff’s encephalitis, 62 bipolar disorder, 115
blepharoplasty, 104 blood glucose, 17, 55
blood tests, 17, 26, 48, 55, 117, 146
botulism, 62
brainstem conditions, 52, 54, 56, 79, 116, 156
breast cancer, 100
bruit, 1, 4, 9, 12. See also tinnitus, pulse-synchronous
C
calcium channel blockers, 139 cancer. See tumors carbamazepine, 61
cardiac disease, 17, 134, 135, 138 carotid arterial system, 2, 3. See
also internal carotid artery carotid-cavernous sinus fistula
(CCF), 1–8, 9–13, 165 carotid occlusive disease, 136,
138, 139 cataracts, 137, 139 catheter angiography
in carotid-cavernous sinus fistulae, 5, 6, 11
in strokes, 22–23
in third nerve palsies, 83–87, 89–91
cat scratch disease, 127–131 cavernous sinus
aneurysms, 55
carotid arterial system and, 2, 3 enlargement, 6
flow voids, 6, 11
Horner syndrome and, 156
170
Index
lesions, 163, 164 neuropathies and, 54 thrombosis or ligation, 28 varix, 5, 6
celiac disease, 99
central nervous system, 45, 110 cerebellar conditions, 52, 79 cerebral angiography, 40, 61,
81–83
cerebral venous sinus thrombosis (CVST), 28–32
cerebritis, 48
cerebrospinal fluid (CSF), 27, 28, 32, 40, 46, 68, 110
chemotherapy, 109, 110, 112 Chiari I malformation, 29 chiasmal syndrome, 147 chiropractic treatment, 155, 157,
158 chlordecone, 29
cholesterol, high levels of, 51, 59, 77, 84
Churg-Strauss syndrome, 99 claustrophobia, 27, 39, 80, 86 coagulopathies, 29, 136, 139.
See also hypercoaguable states
cocaine test, topical, 157–160 cocaine use, 81
Cogan’s lid twitch sign, 52, 79 coiling, endovascular, 7, 12, 91,
95
collagen vascular disease, 52, 68, 79
Collier’s “tucked lid” sign, 60, 61 color vision, 65, 66, 129
compressive optic neuropathy (CON), 98, 101, 102, 104, 105
confrontation visual fields, 25, 51, 77, 97, 147, 149
conjunctiva
chemosis, 4, 5, 52, 54, 79, 98, 99
color, 11 dilatation of, 1 hyperemia, 100
injection, 52, 79, 98, 99 necrosis and superinfection, 4 prolapse, 4
vessels, 9, 11, 12 “conjunctivitis,” 4, 9–11 consciousness, loss of, 147, 149 contrast MRI
in carotid-cavernous sinus fistulae, 6
in cranial nerve palsies, 56, 86 in Horner syndrome, 159
in intracranial abscesses, 46, 48
in pseudotumor cerebri, 39
in Tolosa-Hunt syndrome, 165, 166
in unexplained optic neuropathies, 113
in Wernicke encephalopathy, 116
corectopia, 61
cornea, 4, 5, 101. See also exposure keratopathy
cortical blindness, 61
cortical veins, 3, 5, 11, 28, 31
171
Emergencies in Neuro-Ophthalmology: A Case Based Approach
corticosteroids, 33, 48, 67, 70, 73, 105, 145
cortisol deficiency, 147 cranial nerves, 52, 54, 56, 60,
62, 79, 83. See also third nerve palsies; sixth nerve palsies
craniopharyngioma, 164 C-reactive protein (CRP), 134, 145,
146
Crohn’s disease, 99
CT angiography (CTA), 6, 17, 83, 84, 91, 159
CT perfusion studies, 17, 18 CT scanning
as alternative to MRI, 27, 39, 80
of brain abscesses, 46, 47 for carotid-cavernous sinus
fistula, 6, 11 contrast-enhanced, 80 dynamic, 17
in Horner syndrome, 159 indications, 81, 83, 85 non-contrast, 19, 22, 89, 91,
106
for pseudotumor cerebri, 28 vs MRI and DWI, 19, 20, 62,
149, 158 cycloplegics, 124 cyclosporine, 29 cysticercosis, 100
D danazol, 29
Dandy criteria, 27, 39, 40
demyelinating diseases, 56, 73, 116. See also multiple sclerosis
diabetes
cranial nerve palsies and, 53, 55, 77, 80, 81, 84
Graves’ ophthalmopathy, 104 homonymous hemianopsia and,
15
Horner syndrome and, 155 optic neuritis and, 67 transient visual loss and, 134,
138 dialysis, 40 Diamox, 32, 39
diffusion-weighted imaging (DWI) for detecting stroke, 19, 20, 22,
23, 62
for intracranial abscesses, 46, 47, 48
for Wernicke encephalopathy, 118
diplopia
with carotid-cavernous sinus fistula, 1, 4, 9
with cranial nerve palsies, 51, 77 with giant cell arteritis, 144
with Graves’ ophthalmopathy, 98, 101
sudden, 149
with Wernicke syndrome, 115, 118
diuretics, 39 dizziness, 147
documentation, medical, 18, 32 Doppler flow studies, 11, 134, 138
172
Index
dorsal midbrain syndrome, 27, 59, 60
Duane’s retraction syndrome, 52 dural-cavernous sinus fistula, 100 DWI. See diffusion-weighted
imaging (DWI) dyschromatopsia, 65, 66, 129 dyspepsia, 70
E
Early Treatment of Multiple Sclerosis (ETOMS) Study Group, 71
echocardiography, 134, 139 edema. See also papilledema
cerebral, 27, 28, 48 lid, 9, 12, 52, 79, 98 macular, 4
on MRI studies, 46
optic disc, 33–42, 66, 109, 127–131, 144
periorbital, 98
embolisms, 19, 45, 61, 133–136, 138, 139
embolization, therapeutic, 7 emesis, 89, 115–117
empty sella, 40, 41 empyema, 45
encephalitis, 26, 45, 46, 62. See also Wernicke encephalitis
endarterectomy, 3 endocarditis, 45, 48 episclera, 9, 11, 12 episcleritis, 4 epistaxis, 3
Erdheim-Chester disease, 101
erythema chronica migrans, 68 erythrocyte sedimentation rate
(ESR), 48, 54, 84, 134, 139, 145, 146
erythropsia, 139
esotropia, 51, 52, 54, 101, 115 exercise, 138
exogenous growth hormone, 29 exophthalmos, 4, 98, 101, 105 exotropia, 101
exposure keratopathy, 4, 5, 98, 105
extraocular muscles diplopia and, 4
enlargement, 6, 98, 102, 103 orbital myositis and, 99 palsied, 79, 80
retraction of eye and, 60 eye pain
angle closure glaucoma and, 138
with Graves’ ophthalmopathy, 97 with ODEMS, 128, 129
with optic neuritis, 65
orbital decompression for, 105 with orbital myositis, 99, 100
F
facial nerve, 53 facial pain, 5, 54
facial sensation, 163, 165 fever, 43, 48
fistulae, 100. See also carotidcavernous sinus fistula (CCF)
fluorescein angiography, 129, 137 forced duction test, 52, 79, 101
173
Emergencies in Neuro-Ophthalmology: A Case Based Approach
IV methylprednisolone sodium succinate, 70
fundus examinations, 9, 33, 51, 52, 59, 65, 66, 143
fungal diseases, 46, 74, 100, 165 furosemide, 39
G
gender of patients, 65, 99, 102, 109, 128, 129
giant cell arteritis aspirin and, 145, 146
cranial nerve palsies and, 52, 79, 81, 84
optic neuropathies and, 74 signs and symptoms, 144 transient visual loss, 133, 134,
136–138
vs orbital pseudotumor, 101 giant cell myocarditis, 101 glaucoma
angle closure, 4, 11, 99, 138, 139
carotid-cavernous sinus fistula and, 5, 11
medication, 124 neovascular, 137 gnathostomiasis, 100 Goldmann perimetry
in intracranial abscess, 43, 44 in ODEMS, 127
in pituitary apoplexy, 152, 153 in pseudotumor cerebri, 35, 38 in stroke, 15, 16, 22
in temporal arteritis, 143 granuloma, 45, 146, 166
Graves’ ophthalmopathy (GO), 97–106
H
Halback, VV, 5 headache
bifrontal, 33, 36
in carotid-cavernous sinus fistula, 1
cluster, 99 exclusionary sign, 52
with fever and neurological symptoms, 48
giant cell arteritis and, 54, 84, 144
indications for surgery, 40 misdiagnosis, 144
in ODEMS, 128
in optic neuritis, 67
in pituitary apoplexy, 147, 149, 165
in pseudotumor cerebri, 25, 27, 40
in subarachnoid hemorrhaging, 85
in third nerve palsies, 77, 79, 89 thunderclap, 123
unilateral, 143 with visual loss, 39
head trauma
causing carotid-cavernous sinus fistulae, 3
cerebral abscesses and, 45 cranial CT imaging and, 26, 80 cranial nerve palsies and, 53, 79 intracranial pressure and, 28
174
tissue plasminogen activator (tPA) and, 17
hemianopsia bitemporal, 147–153
homonymous, 15, 16, 19–23, 48, 61
quadrantanopia, 43, 44 hemiparesis, 134 hemiplegia, 52, 54, 79 hemispatial neglect, 44 hemoglobinuria, 28 hemorrhaging. See also
subarachnoid hemorrhaging (SAH)
anterior chamber, 139
CT scanning for, 26, 27, 149 dangerous sign, 6 gastrointestinal, 17 intracerebral, 3, 16, 59, 60 intracranial, 17 intraventricular, 89
with optic disc edema, 33, 66, 111
parenchymal, 89
in pituitary apoplexy, 149 retinal, 4, 137 subconjunctival, 9, 10 urinary tract, 17
vitreous, 4 Henle’s layer, 129 heparin, 17 hepatitis C, 138
herpes zoster ophthalmicus, 100 Hertel measurements, 1, 9, 97 Hodgkin’s disease, 100 Hollenhorst plaques, 134, 135
Index
horizontal gaze palsy, 53 Horner syndrome, 52, 54, 122,
136, 155–162, 164
human immunodeficiency virus (HIV), 67
hydrocephalus, 26, 27, 60 hydrochlorothiazide, 59 hydroxyamphetamine test, 157 hypercholesterolemia, 51, 59, 77,
84
hypercoaguable states, 40, 134, 138
hyperemesis gravidarum, 115, 116 hyperlipidemia, 138
hypertension
bilateral ophthalmoplegia and, 59
cranial nerve palsies and, 53, 55, 77, 81, 84
hemianopsia and, 15 Horner syndrome and, 155 malignant, 26, 130
optic neuritis and, 67 pseudotumor cerebri and, 40 risk factor for stroke, 138 temporal arteritis and, 143 tissue plasminogen activator
(tPA) and, 17 hyperthyroidism, 103, 104 hypertropia, 101 hypervitaminosis A, 28, 29 hyphema, 139 hypoparathyroidism, 29 hypotension, 40 hypothalamus, 118, 156 hypothyroidism, 29
175
Emergencies in Neuro-Ophthalmology: A Case Based Approach
hypotropia, 9 hypoxia, 60
I
iatrogenic conditions, 3, 28, 45, 55, 115, 116, 138
ibuprofen, 33, 143 idiopathic intracranial
hypertension (IIH). See pseudotumor cerebri (PTC)
immunodeficient patients, 46, 113 immunotherapy, 112 indomethacin, 29
infection, 4, 28, 43–49, 67, 113, 129
inflammatory disease, 28, 101 interferon beta-1a, 71, 72 internal carotid artery
in carotid-cavernous sinus fistulae, 2–4, 8, 11
Horner syndrome and, 156, 158, 159, 161, 162
third nerve palsies and, 89 transient visual loss and, 139, 140
International Headache Society (IHS), 165, 166
intracerebral and -cranial abscesses, 45, 46–49
intracranial pressure (ICP), 6, 26, 28, 37, 60, 111
intracranial shunting procedure, 39 intracranial vessels, 6, 26, 27, 40 intraocular pressure (IOP)
with anisocoria, 122
in carotid-cavernous sinus fistula, 1, 5, 9, 11
in early multiple sclerosis, 65 management, 11
in optic neuritis, 65
in pseudotumor cerebri, 25 in third nerve palsies, 77 in thyroid eye disease, 98
iris trauma, 122–124 isotretinoin, 29
J
jaw claudication, 15, 54, 84 jugular veins, 28
K
Kepone, 29 ketaprofen, 29
L
lacrimation, 98, 100 La Mantia, L, 166 Lasix, 77
Leber’s idiopathic stellate neuroretinitis, 128
Leber’s stellate maculopathy, 127 leptomeningeal carcinomatosis, 82 leukemia, 109–113
leukocytosis, 48, 49 lid
Cogan’s lid twitch sign, 52, 79 Collier’s “tucked lid” sign, 60, 61 edema, 9, 12, 52, 79, 98
margin repositioning surgery, 104
retraction, 97, 99, 101, 104, 106, 124
lipid maculopathy, 66
176
Index
lipid storage diseases, 60, 61 lithium, 29, 33
lumbar puncture (LP)
atypical optic neuritis and, 67, 68
cranial nerve palsies and, 54, 55 meningeal signs and, 80, 83 optic disc edema and, 27, 40,
111
subarachnoid hemorrhaging and, 85
lumboperitoneal shunts (LPS), 30, 39
Lyme disease, 28, 67, 68, 100, 130 lymphoid hyperplasia, 100 lymphoma, 28
M
macula, 4, 21, 35, 37, 111, 129, 131
macular star figures, 127–131 magnesium, 116–118 malnutrition, 116
mastoiditis, 28, 45 maxillofacial surgery, 3
meningeal processes, 80, 83, 110, 111
meningeal sarcoidosis, 28 meningioma, 56 meningismus, 85 meningitis, 26, 45, 113
mental status changes, 59, 85, 115–118
metoprolol, 143
middle cerebral artery (MCA), 91, 92, 94
middle ear infections, 45, 165 migraine, 19, 115, 133, 134, 139 Miller-Fisher variant, 62 minocycline, 29
MIP angiography, 61 mononeuritis multiplex, 138
morning glory syndrome, 138, 139 MR angiography (MRA)
for carotid-cavernous sinus fistula, 6, 11
for pseudotumor cerebri, 27 for stroke, 22
in subarachnoid hemorrhaging, 85
in third nerve palsies, 83, 84 in transient visual loss, 138,
139–141
MR imaging (MRI). See also contrast MRI; diffusionweighted imaging (DWI)
of abscesses, 46
in carotid-cavernous sinus fistula, 6, 11
constructive interference in steady state sequences, 56
contraindications, 27, 80, 86 false normals, 62
FLAIR studies, 73, 74, 85, 113, 118, 151
gadolinium enhanced, 71, 74, 80, 161
in Horner syndrome, 156, 157, 159, 160–162
indications, 29, 81, 83, 84
in leukemic infiltration, 111, 112 in multiple sclerosis, 72–74
177
Emergencies in Neuro-Ophthalmology: A Case Based Approach
in pseudotumor cerebri, 27, 30, 40
short tau inversion recovery (STIR) sequence, 102
in stroke, 19, 20, 22
in transient visual loss, 139
vs CT scanning, 19, 20, 86, 91, 102, 149, 158
in Wernicke encephalopathy, 118
MR venography, 27, 29, 30, 32, 39, 40
multiple sclerosis, 60, 67–74, 127, 129
myasthenia gravis
cranial nerve palsies and, 52, 55, 77, 79, 83, 84
differential diagnoses, 52, 62, 77, 99
thyroid eye disease and, 99, 102 mydriasis, 123–25
myocardial infarction, 17
N
nalidixic acid, 29 nasal congestion, 100
nasopharyngeal carcinoma, 164, 165
National Eye Institute, 68 nausea, 33, 89
neonates, 45 neoplasms. See tumors
neuroimaging. See also contrast MRI; CT angiography (CTA); MR angiography (MRA); MR imaging (MRI)
in cerebral venous sinus thrombosis, 28
indications, 16, 22, 26, 39, 54, 55, 158
non-catheter based, 5
in third nerve palsies, 80, 81, 83–87
for visual loss, 69 neuroleptic drugs, 61 neuroretinitis, 128, 130 nifedipine, 139
NIH stroke scale, 16 non-Hodgkin’s lymphoma, 100 nonsteroidal anti-inflammatory
drugs, 97, 99 norepinephrine, 124
nystagmus, 60, 61, 115, 116, 118
O
obesity, 27, 30, 32, 33, 37, 81, 85 occipital lobe lesions, 16, 17, 21,
43, 46, 61
OCT (optical coherence tomography), 9, 33, 35, 37, 143
ocular motility
abduction deficits, 52, 54, 60, 61, 163
adduction deficits, 89, 97, 163,
164
carotid-cavernous sinus fistula and, 1, 4
convergence spasm, 60
in cranial nerve palsies, 51, 77, 78, 89, 123
depression deficits, 89, 163, 164
178
Index
elevation deficits, 9, 10, 89, 163,
164
esotropia, 51, 52, 54, 101, 115 exotropia, 101
fixation instability, 60 in leukemia, 109
nystagmus, 60, 61, 115, 116, 118
pretectal syndrome and, 61 stroke and, 59
in thyroid eye disease, 97
in Tolosa-Hunt syndrome, 163 in Wernicke syndrome, 115,
117
ocular neuromyotonia, 82 oculomotor nerve, 4, 55, 60, 62,
81, 163, 164
oculomotor neurilemmoma, 82 ODEMS (optic disc edema with macular star), 127–131
ophthalmic artery occlusion, 136–138
ophthalmic veins, 3, 4, 6, 11, 102 ophthalmoplegia
in carotid-cavernous sinus fistula, 1, 2, 4, 5, 12
Graves’ ophthalmopathy and, 98, 99, 106
internal, 81
third nerve palsies and, 84, 87,
optic disc, 33–42, 66, 109, 136, 138, 144
optic disc edema with macular star (ODEMS), 127–131
optic nerve, 4, 104, 110–113, 137. See also compressive optic neuropathy (CON)
optic nerve sheath fenestration (ONSF), 30, 39, 40, 42
optic neuritis, 65–75, 127 Optic Neuritis Treatment Trial
(ONTT), 67
oral contraceptives, 25, 29 orbicularis oculi weakness, 52, 79 orbit
congestion, 5, 11, 98, 101 diseases of, 79
fat volume, 98, 102 surgical decompression,
104–106
orbital amyloidosis, 101 orbital cellulitis, 45, 100 orbital myositis, 99–101, 102 orbital polymyositis, 101 Orudis, 29
osteoarthritis, 143 osteopetrosis, 28 osteoporosis, 145 otitis media, 45, 165
95 |
P |
Tolosa-Hunt syndrome and, |
pain. See also eye pain; headache |
163–167 |
ear, 144 |
Wernicke encephalitis and, 116, |
facial, 5, 54 |
117 |
jaw, 143, 144 |
optic chiasm, 15, 21, 147 |
neck, 21, 144, 155, 157 |
179
Emergencies in Neuro-Ophthalmology: A Case Based Approach
when combing hair, 143 pamidronate, 101 panhypopituitarism, 147, 149 panuveitis, 137
papilledema etiologies, 27, 29
management, 26, 27, 29–30, 32, 39
in pseudotumor cerebri, 26, 39 signs and symptoms, 36, 37,
40
sixth nerve palsies and, 56 typical profile, 39
use of term, 37
vs leukemic infiltration of optic nerve, 111
vs ODEMS, 130 parasympathicolytic drugs, 124 parenteral nutrition, 116
parietal lobe lesions, 21, 43, 139 Parkinson’s disease, 61 penicillin, 155
peripapillary exudates, 128 peripapillary staphyloma, 138, 139 phenylephrine, 124
photophobia, 89, 98
piercings causing infection, 43–49 pilocarpine, 122–124
pituitary adenoma, 164 pituitary apoplexy, 74, 85,
147–153, 165 pleocytosis, 68 polycythemia vera, 138
polymyalgia rheumatica, 84, 145 posterior cerebral artery, 22, 23 posterior ciliary artery, 137
posterior communicating artery, 86, 89, 91, 92, 94
post-partum patients, 29, 115 prednisone, 70, 145, 146 pregnancy, 27, 29, 40 pretectal syndrome, 60 proptosis
alternative etiologies, 99 carotid-cavernous sinus fistula
and, 1, 3–6, 9, 12
cranial nerve palsies and, 54, 79 exclusionary sign, 52
Graves’ ophthalmopathy and, 98, 102, 104
orbital myositis and, 100, 102 surgical decompression, 105
prostate cancer, 101 protein S deficiency, 28 protime (PT), 17 pseudoabducens palsy, 61 pseudoaneurysms, 5
pseudotumor cerebri (PTC), 26–32, 39, 40
psychosocial factors, 40, 70 ptosis
absence of, 21 bilateral, 60 exclusionary sign, 52
Horner syndrome and, 155, 156, 159–161
orbital myositis and, 99
sign of carotid-cavernous sinus fistula, 1, 2, 9, 12
with third nerve palsy, 77–79, 87, 89
pulmonary apex, 159
180
Index
pupillary sphincter, 79, 80, 164 pupils. See also anisocoria; relative
afferent pupillary defect (RAPD)
abnormalities, 61
dilated, 82, 122–124, 138 dilation lag, 155, 156 fixed, 164
light-near dissociation, 59, 60, 115
tonic, 82, 122–124 Purtscher’s retinopathy, 137
R
radiculopathies, 52, 79, 83 radiotherapy, 103, 105, 110, 112 RAI (radioiodine therapy), 103 red eye, 5, 10–12
relative afferent pupillary defect (RAPD), 65, 66, 74, 127
renal failure, 29, 40
retina, 4, 5, 66, 67, 110, 111, 129 retinal artery and vein occlusion,
4, 26, 67, 134, 136, 137, 139 retinal capillary telangiectasia, 137 “retinal migraine,” 133
retinal pigment epithelium (RPE), 42, 131
retrochiasmal lesions, 15, 21 retro-Gasserian procedures, 3 rheumatoid arthritis, 97, 99 Rosai-Dorfman disease, 100 Rosenmuller, fossa of, 165
S
sarcoidosis, 29, 67, 68, 99, 101
“Savino’s rule,” 122
scleral buckle procedure, 138 scleroderma, linear, 99 scopolamine, 124, 125 scotoma
central, 35, 38, 42, 127 junctional, 74 scintillation, 134
seizures, 17, 19 seminoma, 100
sexual intercourse, 138 shunts, 27, 30, 39, 40, 60 sildenafil citrate, 81
sinuses. See also cavernous sinus basilar, 3
intercavernous, 3 lateral, 28 sigmoid, 28
sphenoidal, 68, 165 straight, 28
superior sagittal, 28, 29, 30,
31 sinusitis, 45, 67
sixth nerve palsies, 33, 40, 51–57, 163, 165
skew deviation, 61, 117 sleep disturbances, 70 slit lamp examination
assessing anisocoria, 122, 123 in carotid-cavernous sinus
fistula, 1, 9
in early multiple sclerosis, 65 in leukemia patient, 109
in stroke, 15, 59
in third nerve palsy, 77 in thyroid eye disease, 97
181
Emergencies in Neuro-Ophthalmology: A Case Based Approach
smoking, 81, 103–104, 106, 133, 134, 138
spatial disorientation, 44 spinal cord, 109
spinal tap. See lumbar puncture (LP)
statin therapy, 51, 77 stenting, 19, 29 stereopsis, 66 steroids
ODEMS and, 130
optic neuropathy and, 67, 70, 106
orbital myositis and, 99 pseudotumor cerebri and, 29 temporal arteritis and, 145 Tolosa-Hunt syndrome and, 165,
167 strabismus, 99, 104 stroke
in carotid-cavernous sinus fistula treatment, 8
etiologies, 19
homonymous hemianopsia and, 15–20
Horner syndrome and, 158, 159 mimic, 19
risk factors, 134, 138
signs and symptoms, 15–17, 21, 59–61
treatment, 16–20, 22, 23, 61–63 subarachnoid hemorrhaging (SAH)
carotid-cavernous sinus fistula and, 3, 6
catheter angiography and, 89, 90 cranial nerve palsies and, 56, 85
CT scanning for, 81, 83 intracranial pressure and, 26 pupil dilation and, 123 tissue plasminogen activator
(tPA) and, 17
superior vena cava syndrome, 28
surgical decompression, 104–106, 147–149
syphilis, 61, 68, 130 systemic lupus erythematosus
(SLE), 28, 29, 67, 81, 99, 101, 138
T
telemedicine, 19
temporal arteritis, 55, 143–146 temporal artery biopsies, 55, 84,
145, 146
temporal lobe lesions, 21, 61 tetracyclines, 29, 33 thiamine, 116–118
third nerve palsies, 62, 77–87, 89–96, 122–124, 156
thrombocythemia, 28 thromboembolic disease, 22, 135,
139, 158
thrombolytic treatments, 18, 29 thrombosis, 3, 5, 6, 28, 40 thyroid eye disease, 9, 97–106 thyroid replacement, 29
tinnitus, pulse-synchronous, 4, 33, 36
tissue plasminogen activator (tPA), 16–19, 22, 61, 62
Todd’s paralysis, 19
182
Index
Tolosa-Hunt syndrome, 82, 165–167
tongue claudication, 84 tonsillitis, 45 topirimate, 39 toxoplasmosis, 130
tPA. See tissue plasminogen activator (tPA)
transient ischemic attacks, 6 transient visual obscurations
(TVOs), 33, 36 transphenoidal surgery, 3 tretinoin, 29
trichinosis, 28, 100
trigeminal nerve, 3–5, 163, 165 tuberculosis, 61, 67
tumors. See also leukemia; pseudotumor cerebri (PTC)
cardiac nerve palsies and, 55, 82
cavernous sinus syndrome and, 164, 165
on CT or contrast MRI scans, 48, 116
dorsal midbrain damage and, 60
glomus jugulare, 28
Horner syndrome and, 158, 159 Pancoast, 158
parasellar, 82
vs orbital pseudotumors, 100
U
ultrasonography, 5, 11, 102, 106, 138
uveitis, 67, 124
V
vasculitis, 40, 61 ventriculomegaly, 27 ventriculoperitoneal shunts (VPS),
27, 30, 39, 40 verapamil, 139
vertebral arterial dissection, 21 vertebral-basilar atherosclerotic
disease, 19 vestibuloocular reflex, 59 Viagra, 81
viral illness, 127, 129, 130 visual field defects. See also Goldmann perimetry
with intracranial abscesses, 43 in optic neuritis, 66, 70, 74,
147
in stroke, 15, 16, 23, 135 visual loss
in carotid-cavernous sinus fistula, 4, 5, 8
giant cell arteritis and, 54, 144 leukemic infiltration and, 110 ODEMS and, 127, 128
optic nerve sheath fenestration and, 39
postprandial, 136
shunt dysfunction and, 27 steroids for, 145
sudden, 149
“Swiss cheese” pattern, 135 thyroid eye disease and, 101 transient monocular, 133–142,
144, 145
visual symptoms. See also diplopia; hemianopsia;
183
Emergencies in Neuro-Ophthalmology: A Case Based Approach
scotoma; visual field defects; visual loss
blurred vision, 25, 33, 115, 147
contrast sensitivity, 66 cotton wool spots, 66, 137 diminished acuity, 6
dyschromatopsia, 65, 66, 129 erythropsia, 139 light-brightness, 66 photopsia, 135
stereopsis, 66
transient visual obscurations, 33
vitamin A and analogs, 28, 29, 33
vitamin deficiencies and excesses, 28, 29, 61, 117
vomiting, 89, 115–117
W
Wallenberg syndrome, 159 warfarin, 158
Wegener’s granulomatosis, 67, 99, 101
weight gain, 33, 70 weight loss, 143
Wernicke encephalitis, 62, 115–118
Whipple’s disease, 61, 62, 99 Willis, circle of, 61, 62 Wilson’s disease, 61
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