Maria Sabina Ahchu, M.D.

Pediatric Hematologist/Oncologist

Hospital del Niño de Panamá

Panama, Republic of Panama

J. Thomas Ford

Trustee, Board Member

Director, and Past President Programa Niños

Sanos: Niños Felices

Panama, Republic of Panama

Honduras

Ligia Fu, M.D.

Pediatric Hematologist/Oncologist & Medical

Director

Hospital Escuela Materno Infantil

Tegucigalpa, Honduras

Carlos Maldonado, M.D.

Ophthalmologist

Hospital Escuela Materno Infantil

Tegucigalpa, Honduras

Lilia Lopez, M.D.

Ophthalmologist

Hospital Escuela Materno Infantil

Tegucigalpa, Honduras

Selected References

Abramson DH, Beaverson K, Sangani P, Vora R, Lee T, Hochberg H, Kirszrot J, Ranjithan M (2003) Screening for retinoblastoma: presenting signs as prognosticators of patient and ocular survival. Pediatrics 112(6):1248–1255

Balaguer J, Wilson MW, Billups CA, Mancini J, Haik BG, Qaddoumi I, Khoury JD, Rodriguez-Galindo C (2009) Predictive factors of invasion in eyes with retinoblastoma enucleated after eye salvage treatments. Pediatr Blood Cancer 52(3):351–356

Carlos LL, Roberto RL, Victor TG, Carlos HG, Eduardo LP (2002) Risk of dying of retinoblastoma in Mexican children. Med Pediatr Oncol 38(3):211–213

Chantada G, Fandino A, Manzitti J, Urrutia E, Schvartzman E (1999) Late diagnosis of retinoblastoma in a developing country. Arch Dis Child 80(2):171–174

Connolly D (2007) Hamilton institute quickly gaining global reputation. Commercial appeal. http://www. eye.uthsc.edu/news/CommercialApp-Jan07.pdf. Accessed 4 Jan 2007

Cyber-Sight website (2007) Retinoblastoma: one world, one vision. http://cybersight.org/bins/content_page. asp?cid=70–2151. Accessed Jan 2007

Dome Jeffrey S, Rodriguez-Galindo Carlos, Spunt Sheri L, Santana Victor M (2008) Pediatric solid tumors. In: Abeloff Martin D (ed) Abeloff’s clinical oncology, 4th edn. Elsevier, Philadelphia, pp 2075–2129

Dyer MA (2009) In their own words: interviews with cell cycle. The first knockout mouse model of retinoblastoma. Cell Cycle 8(14):2145, Epub 2009 Jul 15. PMID: 19574732

Ellsworth R (1969) The practical management of retinoblastoma. Trans Am Ophthalmol Soc 67:462–534 Finger PT; 7th Edition, AJCC-UICC Ophthalmic

Oncology Task Force (committee of 45 members including Haik BG and Wilson MW) (2009) The 7th edition AJCC staging system for eye cancer: an international language for ophthalmic oncology. Arch Pathol Lab Med 133(8):1197–1198. PMID: 19653708

Friend SH, Bernards R, Rogelj S, Weinberg RA, Rapaport JM, Albert DM, Dryja TP (1986) A human DNA segment with properties of the gene that predisposes to retinoblastoma and osteosarcoma. Nature 323(6089):643–646

Haynie HW (2008) Hamilton eye institute expands reach of telemedicine. West Tennessee Medical News. http:// www.westtnmedicalnews.com/news.php?viewStory= 1397. Accessed Jul 2008

Helveston EM, Thazhathu MJ, Smallwood LM (2006) ORBIS telemedicine, cyber-sight. In: Yogesan K, Kumar S, Goldschmidt L, Cuadros J (eds) Teleophthalmology. Springer, Berlin/Heidelberg, pp 187–193

Knudson AG Jr (1971) Mutation and cancer: statistical study of retinoblastoma. Proc Natl Acad Sci U S A 68(4):820–823

Lawrence SD, Hoehn ME, Karcioglu ZA, Haik BG (2009) An unusual case of retinoblastoma. Ophthalmic Surg Lasers Imaging 40(3):296–299, PubMed PMID: 19485296

Leander C, Fu LC, Peña A, Howard SC, RodriguezGalindo C, Wilimas JA, Ribeiro RC, Haik B (2007) Impact of an education program on late diagnosis of retinoblastoma in Honduras. Pediatr Blood Cancer 49(6):817–819

Rodrigues KE, Latorre MR, de Camargo B (2004) Delayed diagnosis in retinoblastoma. J Pediatr 80(6):511–516 Rodriguez-Galindo C, Wilson MW (eds) (2010)

Retinoblastoma. Springer, New York Rodriguez-Galindo C, Wilson MW, Chantada G, Fu L,

Qaddoumi I, Antoneli C, Leal-Leal C, Sharma T, Barnoya M, Epelman S, Pizzarello L, Kane JR, Barfield R, Merchant TE, Robison LL, Murphree AL, Chevez-Barrios P, Dyer MA, O’Brien J, Ribeiro RC, Hungerford J, Helveston EM, Haik BG, Wilimas J (2008) Retinoblastoma: one world, one vision. Pediatrics 122(3):e763–e770, Review. PMID: 18762512

Sastre X, Chantada GL, Doz F, Wilson MW, de Davila MT, Rodríguez-Galindo C, Chintagumpala M, Chévez-Barrios P (2009) International Retinoblastoma Staging Working Group. Proceedings of the consensus

meetings from the International Retinoblastoma Staging Working Group on the pathology guidelines for the examination of enucleated eyes and evaluation of prognostic risk factors in retinoblastoma. Arch Pathol Lab Med 133(8):1199–1202, PMID: 19653709

Shepard S (2006) Discovery by UT-St. Jude scientific team seen as breakthrough in cancer research. Memphis Bus J h t t p : / / w w w . b i z j o u r n a l s . c o m / m e m p h i s / stories/2006/11/13/story8.html?page=all

Shih CS, Laurie N, Holzmacher J, Spence Y, Nathwani AC, Davidoff AM, Dyer MA (2009) AAV-mediated local delivery of interferon-beta for the treatment of retinoblastoma in preclinical models. Neuromolecular Med 11(1):43–52, Epub 2009 Mar 22. PMID: 19306089

St. Jude Children’s Research Hospital (2009) Outreach through Oncopedia. Promise http://www.stjude.org/ stjude/v/index.jsp?vgnextoid=55e6cde1a67df110Vgn VCM1000001e0215acRCRD. Accessed Winter 2009 Strehlau C (2006) Retinoblastoma symposium with Drs. Barrett Haik, Judith Wilimas, and Eugene Helveston. St. Jude Medical Minute. http://www.eye.uthsc.edu/audio/

stjude-medmin-panama.mp3. Accessed 11 Jan 2006 Sutherland J (2006) Mission possible: UTMG ophthal-

mologists make a difference in Panama. Link UT Medical Group http://www.bizjournals.com/memphis/ stories/2006/11/13/story8.html?page=all

UT Health Science Center (2007) University of Tennessee Health Science Center Hamilton Eye Institute uses telemedicine to reach out to Panamanian patients. http://www.uthsc.edu/news/ne.php?HYPER=/news/ november/hei_panama_teleconference_release.htm. Accessed 28 Nov 2007

UT Health Science Center (2008) Vietnam Telehealth Conference, Hamilton Eye Institute. The Record. http://www.uthsc.edu/record/pdfs/2008/record_mayjun08.pdf. Accessed May-June 2008

WHBQ-TV Memphis (Fox affiliate) (2006) International symposium aboard ORBIS® flying eye hospital. Fox 13 Eyewitness News. http://www.eye.uthsc.edu/video/ Orbis-Fox13news-2006jan13.mpg. Accessed 13 Jan 2006

WHBQ-TV Memphis (Fox affiliate) (2006) Health matters: targeted retinoblastoma therapy. Fox 13 Eyewitness News. http://www.eye.uthsc.edu/video/ RB-Ch13FoxNews-Dec5–2006.wmv. Accessed 5 Dec 2006

Wilimas JA, Wilson MW, Haik BG, Barnoya M, Fu L, Castellanos M, Bonilla M, Phillips BX, Helveston EM, Luna-Fineman S, Ribiero R, Rodriguez-Galindo C (2009) Development of retinoblastoma programs in Central America. Pediatr Blood Cancer 53(1):42–46

Wilson MW, Rodriguez-Galindo C, Billups C, Haik BG, Laningham F, Patay Z (2009a) Lack of correlation between the histologic and magnetic resonance imaging results of optic nerve involvement in eyes primarily enucleated for retinoblastoma. Ophthalmology 116(8):1558–1563, Epub 2009 Jul 9. PubMed PMID: 19545904

Wilson MW, Fraga CH, Rodriguez-Galindo C, Hagedorn N, Leggas ML, Stewart C (2009b) Expression of the multi-drug resistance proteins and the pregnane X receptor in treated and untreated retinoblastoma. Curr Eye Res 34(5):386–394

Preamble

The American Telemedicine Association (ATA), with members from throughout the USA and the world, is the principal organization bringing together telemedicine practitioners, healthcare institutions, vendors, and others involved in providing remote healthcare using telecommunications. The ATA is a nonproÞt organization that seeks to bring together diverse groups from traditional medicine, academia, technology and telecommunications companies, e-health, allied professional and nursing associations, medical societies, government, and others to overcome barriers to the advancement of telemedicine through the professional, ethical, and equitable improvement in healthcare delivery.

ATA has embarked on an effort to establish practice guidelines and technical standards for telemedicine to help advance the science and to assure uniform quality of service to patients. Guidelines and standards are developed by panels that include experts from the Þeld and other strategic stakeholders. The guidelines are designed to serve as an operational reference and educational tools to aid providing appropriate care for patients. The guidelines and standards generated by ATA undergo a thorough consensus and rigorous review, with Þnal approval by the ATA board of directors. Recommendations will be reviewed and updated periodically.

The practice of medicine is an integration of the science and art of preventing, diagnosing, and treating diseases. It should be recognized that adherence to these guidelines and standards will not guarantee accurate diagnoses or successful outcomes. The purpose of these guidelines and standards is to assist practitioners in pursuing a sound course of action to provide effective and safe medical care founded on current information and evidence-based medicine, available resources, and patient needs. ATA recognizes that safe and effective practice requires speciÞc training, skills, and techniques as described in this document.

The goal of Telehealth Practice Recommendations for Diabetic Retinopathy is to support telehealth programs to improve clinical outcomes and promote reasonable and informed patient and care provider expectations. Recommendations are based on reviews of current evidence, medical literature, and clinical practice. The recommendations are not intended as strict requirements. They may need to be adapted for patient care or situations where more or less stringent interventions are necessary. Recommendations are also not intended to serve as legal advice or as a substitute for legal counsel. This document does not replace sound medical judgment or clinical decision-making. Supplemental information and examples are included in the appendix.

This document is property of ATA. Any reproduction or modiÞcation of the published practice guideline and technical standards must receive prior approval by ATA.