- •Foreword
- •Preface
- •Contents
- •1.1 Introduction
- •1.2 Method
- •1.2.1 Databases
- •1.2.2 Dates
- •1.2.3 Keywords
- •1.2.4 Criteria for Inclusion
- •1.2.5 Criteria for Exclusion
- •1.2.6 Selection of Papers
- •1.3 Results
- •1.3.1 Subspecialty
- •1.3.2 Type of Telemedicine
- •1.3.3 Study Design
- •1.3.4 Final Conclusions of Papers
- •1.4 Discussion
- •References
- •2.1 Introduction
- •2.2 The Need for Diabetic Retinopathy Screening Programs
- •2.4 Guidelines for Referring Patients
- •2.7 Program Models for Diabetic Retinopathy Screening
- •2.9 Program Personnel and Operations
- •2.9.1 Primary Care Providers
- •2.9.2 Photographers
- •2.9.3 Clinical Consultants
- •2.9.4 Administrators
- •2.9.5 A Note to CEOs, Operations Directors, and Clinic Managers
- •2.10 Policies and Procedures
- •2.10.1 Sample Protocol 1
- •2.10.1.1 Diabetic Retinopathy Screening Services
- •Policy
- •Background
- •Procedure
- •2.10.2 Sample Protocol 2
- •2.10.2.1 Pupil Dilation Before Diabetic Retinopathy Photography
- •Policy
- •Background
- •Procedure
- •2.10.3 Sample Protocol 3
- •2.10.3.1 Diabetic Retinopathy Photography Review
- •Policy
- •Background
- •Procedure
- •2.11 Technical Requirements
- •2.11.1 Connectivity
- •2.11.2 Resolution
- •2.11.3 Color
- •2.11.4 Stereopsis
- •2.11.5 Compression
- •2.11.6 Enhancement
- •2.11.7 Pupil Dilation
- •2.11.8 Early California Telemedicine Initiatives Diabetic Retinopathy Screening
- •2.11.9 The American Indian Diabetes Teleophthalmology Grant Program
- •2.11.10 Central Valley EyePACS Diabetic Retinopathy Screening Project
- •2.12.1 Diabetic Retinopathy
- •2.12.1.1 ADA Guidelines Terms
- •2.12.1.2 Vitrectomy
- •References
- •3: Stereopsis and Teleophthalmology
- •3.1 Introduction
- •3.2 History of Stereopsis and Stereopsis in Ophthalmology
- •3.3 Technology and Photography
- •3.3.3 Imaging Fields
- •3.3.4 Image Viewing Techniques
- •3.3.5 Image Compression
- •3.4 Stereoscopic Teleophthalmology Systems
- •3.4.1 University of Alberta
- •3.4.4 Joslin Vision Network
- •3.5 Conclusion
- •References
- •4.1 Introduction
- •4.2 Methods
- •4.2.1 Main Outcome Measures
- •4.3 Results
- •4.3.1 Retinal Video Recording Versus Retinal Still Photography
- •4.3.2 Video Compression Analysis
- •4.4 Discussion
- •References
- •5.1 Introduction
- •5.1.1 Automated, Remote Image Analysis of Retinal Diseases
- •5.1.2 Telehealth
- •5.2 Design Requirements
- •5.2.1 Telehealth Network Architecture
- •5.2.2 Work Flow
- •5.2.3 Performance Evaluation of the Network
- •5.3 Automated Image Analysis Overview
- •5.3.1 Quality Assessment Module
- •5.3.2 Vascular Tree Segmentation
- •5.3.3 Quality Evaluation
- •5.4 Anatomic Structure Segmentation
- •5.4.1 Optic Nerve Detection
- •5.4.2 Macula
- •5.4.3 Lesion Segmentation
- •5.4.4 Lesion Population Description
- •5.4.5 Image Query
- •5.5 Summary
- •References
- •6.1 Introduction
- •6.3 Optical Coherence Tomography to Detect Leakage
- •References
- •7.1 Introduction
- •7.2 Patients and Methods
- •7.2.1 Participants
- •7.2.2 Methods
- •7.2.3 Statistics
- •7.3 Results
- •7.3.1 Reliability of Image Evaluation
- •7.3.2 Prevalence of Glaucomatous Optic Nerve Atrophy
- •7.4 Discussion
- •7.5 Perspectives
- •References
- •8.1 Introduction
- •8.1.2 Homology Between Retinal and Systemic Microvasculature
- •8.1.3 Need for More Precise CVD Risk Prediction
- •8.2.1 Retinal Microvascular Signs
- •8.2.2 Retinal Vessel Biometry
- •8.2.3 Newer Retinal Imaging for Morphologic Features of Retinal Vasculature
- •8.3 Associations of Retinal Imaging and CVD Risk
- •8.3.1.1 Risk of Pre-clinical CVD
- •8.3.1.2 Risk of Stroke
- •8.3.1.3 Risk of Coronary Heart Disease
- •8.3.2.1 Risk of Hypertension
- •8.3.2.2 Risk of Stroke
- •8.3.2.3 Risk of Coronary Heart Disease
- •8.3.2.4 Risk of Peripheral Artery Disease
- •8.3.3 Newer Morphologic Features of Retinal Vasculature
- •8.4 Retinal Imaging and Its Potential as a Tool for CVD Risk Prediction
- •References
- •9.1 Alzheimer’s Disease
- •9.2 Treatments
- •9.3 Diagnosis
- •9.6 Conclusions
- •References
- •10.1 Introduction
- •10.1.1 Stroke
- •10.1.2 Heart Disease
- •10.1.3 Arteriovenous Ratio
- •10.2 Purpose
- •10.3 Method
- •10.3.1 Medical Approach
- •10.3.2 Technical Approach
- •10.3.3 Output of Medical Data
- •10.4 Patients
- •10.5 Results
- •10.5.1 Medical History
- •10.5.2 Telemedical Evaluation of Retinal Vessels
- •10.5.2.1 Prevalence of Retinal Microangiopathy
- •10.5.2.2 Arteriovenous Ratio
- •10.5.2.3 PROCAM-Index
- •10.6 Discussion and Perceptive
- •10.6.1 Estimation of “Stroke Risk” Estimated by the Stage of Retinal Microangiopathy
- •References
- •11.1 Introduction
- •11.2 System Requirements
- •11.3 Fundus Camera
- •11.4 Imaging Procedure
- •11.4.1 Reading Center Procedure
- •11.5 Detection of Macular Edema
- •11.6 Implementation
- •11.7 Unreadable Images
- •11.7.1 Impact on Overall Diabetic Retinopathy Assessment Rates
- •11.7.2 Compliance with Recommendations
- •11.7.3 Challenges
- •11.7.4 Summary
- •References
- •12.1 Screening
- •12.2 Background
- •12.3 Historical Perspective in England
- •12.4 Methodology
- •12.4.1 The Aim of the Programme
- •12.5 Systematic DR Screening
- •12.6 Cameras for Use in the English Screening Programme
- •12.7 Software for Use in the English Screening Programme
- •12.9 Implementation in England
- •12.11 Quality Assurance
- •12.12 The Development of External Quality Assurance in the English Screening Programme
- •12.13 Information Technology (IT) Developments for the English Screening Programme
- •12.14 Dataset Development
- •12.15 The Development of External Quality Assurance Test Set for the English Screening Programme
- •12.16 Failsafe
- •12.17 The Epidemic of Diabetes
- •References
- •13.1 Introduction
- •13.2 Burden of Diabetes and Diabetic Retinopathy in India
- •13.3 Diabetic Retinopathy Screening Models
- •13.4 Need for Telescreening
- •13.5 Guidelines for Telescreening
- •13.6 ATA Categories of DR Telescreening Validation
- •13.7 Yield of Diabetic Retinopathy in a Telescreening Model
- •13.8 How Are Images Transferred
- •13.10 How Many Fields Are Enough for Diabetic Retinopathy Screening
- •13.11 Is Mydriasis Needed While Using Nonmydriatic Camera?
- •13.12 Validation Studies on Telescreening
- •13.12.1 Accuracy of Telescreening
- •13.12.2 Patient Satisfaction in Telescreening
- •13.12.3 Cost Effectivity
- •13.12.4 Telescreening for Diabetic Retinopathy: Our Experience
- •13.13 Future of Diabetic Retinopathy Screening
- •References
- •14.1 Introduction
- •14.2 Methods
- •14.3 Discussion
- •14.4 Conclusion
- •References
- •15.1 Introduction
- •15.1.1 Description of the EADRSI
- •15.5 State Support of Screening in the Safety Net
- •15.7 Screening Economics for Providers
- •15.8 Patient Sensitivity to Fees
- •15.9 Conclusion
- •References
- •16.1 Introduction
- •16.2 Setting Up the New Screening Model
- •16.2.1 Phase 1: Training
- •16.2.2 Phase 2: Evaluation of Agreement
- •16.2.3 Phase 3: Implementation of the Screening Model
- •16.3 Technologic Requirements
- •16.3.1 Data Management
- •16.3.2 Data Models
- •16.3.2.1 Data Scheme for Patient-Related Information
- •16.3.2.2 Data Scheme for Images
- •Fundus Camera VISUCAM Pro NM
- •PACS Server
- •ClearCanvas DICOM Visualizer
- •16.4 Results
- •16.4.1 Phase 2: Agreement Evaluation
- •16.4.2 Phase 3: Implementation of the Screening Model
- •16.5 Discussion
- •16.5.1 Evaluation of the Screening Model
- •16.5.2 Prevalence of DR
- •16.5.3 Quality Evaluation
- •16.6 Conclusion
- •References
- •17.1.3 Examination and Treatment
- •17.1.4 Limitations of Current Care
- •17.2 Telemedicine and ROP
- •17.2.2 Accuracy and Reliability of Telemedicine for ROP Diagnosis
- •17.2.3 Operational ROP Telemedicine Systems
- •17.2.4 Potential Barriers
- •17.3 Closing Remarks
- •17.3.1 Future Directions
- •References
- •18.1 Introduction
- •18.2 Neonatal Stress and Pain
- •18.3 ROP Screening Technique
- •18.4 Effect of Different Examination Techniques on Stress
- •18.5 Future of Retinal Imaging in Babies
- •References
- •19.1 Introduction
- •19.2 History of the Program
- •19.3 Telehealth Technologies
- •19.4 Impact of the Program
- •Selected References
- •Preamble
- •Introduction
- •Background
- •The Diabetic Retinopathy Study (DRS)
- •Mission
- •Vision
- •Goals
- •Guiding Principles
- •Ethics
- •Clinical Validation
- •Category 1
- •Category 2
- •Category 3
- •Category 4
- •Communication
- •Medical Care Supervision
- •Patient Care Coordinator
- •Image Acquisition
- •Image Review and Evaluation
- •Information Systems
- •Interoperability
- •Image Acquisition
- •Compression
- •Data Communication and Transmission
- •Computer Display
- •Archiving and Retrieval
- •Security
- •Reliability and Redundancy
- •Documentation
- •Image Analysis
- •Legal Requirements
- •Facility Accreditation
- •Privileging and Credentialing
- •Stark Act and Self-referrals
- •State Medical Practice Acts/Licensure
- •Tort Liability
- •Duty
- •Standards of Care
- •Consent
- •Quality Control
- •Operations
- •Customer Support
- •Originating Site
- •Transmission
- •Distant Site
- •Financial Factors
- •Reimbursement
- •Grants
- •Federal Programs
- •Other Financial Factors
- •Equipment Cost
- •Summary
- •Abbreviations
- •Appendices
- •Appendix A: Interoperability
- •Appendix B: DICOM Metadata
- •Appendix C: Computer-Aided Detection
- •Appendix D: Health Insurance Portability and Accountability Act (HIPAA)
- •Appendix F: Quality Control
- •Appendix H: Customer Support
- •Level 1
- •Level 2
- •Level 3
- •Appendix I: Reimbursement
- •Medicare
- •Medicaid
- •Commercial Insurance Carrier Reimbursement
- •Other Financial Factors
- •Disease Prevention
- •Resource Utilization
- •American Telemedicine Association’s Telehealth Practice Recommendations for Diabetic Retinopathy
- •Conclusion
- •References
- •Contributors
- •Second Edition
- •First Edition
- •Index
Contents
Part I The Current State of the Art and Future Trends
1 |
A Literature Review of Teleophthalmology Projects |
|
|
from Around the Globe . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . |
3 |
|
Kambiz Bahaadinbeigy and Kanagasingam Yogesan |
|
2 |
Diabetic Retinopathy Screening Practice Guide . . . . . . . . . . . |
11 |
|
Jorge Cuadros and Christine Martin |
|
3 |
Stereopsis and Teleophthalmology. . . . . . . . . . . . . . . . . . . . . . . |
31 |
|
Beatrice K. Wong, Chris J. Rudnisky, |
|
|
and Matthew T.S. Tennant |
|
4 |
Video Imaging Technology: A Novel Method |
|
|
for Diabetic Retinopathy Screening. . . . . . . . . . . . . . . . . . . . . . |
37 |
|
Daniel Ting, Kanagasingam Yogesan, Ian Constable, |
|
|
and Mei-Ling Tay-Kearney |
|
5 |
Automated Image Analysis and the Application |
|
|
of Diagnostic Algorithms in an Ocular |
|
|
Telehealth Network . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . |
43 |
|
Thomas P. Karnowski, Yaqin Li, Luca Giancardo, |
|
|
Deniz Aykac, Kenneth W. Tobin, and Edward Chaum |
|
6 |
Computer-Aided Detection of Diabetic |
|
|
Retinopathy Progression. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . |
59 |
|
José Cunha-Vaz, Rui Bernardes, Torcato Santos, Carlos Oliveira, |
|
|
Conceição Lobo, Isabel Pires, and Luisa Ribeiro |
|
7 |
Tele-glaucoma: Experiences and Perspectives . . . . . . . . . . . . . |
67 |
|
Georg Michelson, Rüdiger Bock, Simone Wärntges, |
|
|
Joachim Hornegger, Berthold Lausen, and Werner Adler |
|
8 |
Retinal Vascular Imaging for Cardiovascular |
|
|
Risk Prediction . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . |
77 |
|
Ryo Kawasaki and Tien Yin Wong |
|
9 |
Retinal Screening for Early Detection |
|
|
of Alzheimer’s Disease . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . |
91 |
|
Shaun Frost, Ralph N. Martins, and Kanagasingam Yogesan |
|
ix
x |
Contents |
|
|
10 Screening the Retina for Heart Disease/Stroke
(talkingeyes®) . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 101 Georg Michelson and Martin Laser
Part II The Telemedicine Applications
and Global Experience: Teleretinal Imaging in Adults
11Diabetic Retinopathy Assessment in the Primary Care Environment: Lessons Learned from 100,000
Patient Encounters . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 117
Ingrid E. Zimmer-Galler
12 |
The Systematic DR Screening in England |
|
|
for Two Million People with Diabetes . . . . . . . . . . . . . . . . . . . . |
127 |
|
Peter H. Scanlon |
|
13 |
Telescreening for Diabetic Retinopathy |
|
|
in South India . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . |
137 |
|
Tarun Sharma, Rajiv Raman, |
|
|
Sheila John, and S.S. Badrinath |
|
14 |
First Experience with Teleophthalmology |
|
|
in Rural Nepal . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . |
143 |
|
J. Niklas Ulrich |
|
15 |
Economics of Screening for Diabetic Retinopathy |
|
|
Using Telemedicine in California’s Safety Net . . . . . . . . . . . . . |
147 |
|
Robert Quade and Veenu Aulakh |
|
16 |
Diabetic Retinopathy Screening with Nonmydriatic |
|
|
Retinography by General Practitioners . . . . . . . . . . . . . . . . . . |
157 |
|
José Andonegui, Luis Serrano, Aitor Egúzkiza, |
|
|
Mikel Auzmendi, Ane Zurutuza, |
|
|
and Mónica Pérez de Arcelus |
|
Part III The Telemedicine Applications
and Global Experience: Paediatric Applications
17 |
Telemedicine for Retinopathy |
|
|
of Prematurity Diagnosis . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . |
169 |
|
Camila Vieira Oliveira Carvalho Ventura, |
|
|
Steven L. Williams, and Michael F. Chiang |
|
18 |
Retinal Examination in Premature Babies . . . . . . . . . . . . . . . . |
177 |
|
Yogavijayan Kandasamy |
|
19 |
Retinoblastoma Management: Connecting |
|
|
Institutions with Telemedicine . . . . . . . . . . . . . . . . . . . . . . . . . . |
181 |
|
Barrett G. Haik |
|
Appendix . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . |
193 |
|
Index. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . |
225 |
|
Part I
The Current State of the Art and Future Trends
A Literature Review |
1 |
of Teleophthalmology |
Projects from Around the Globe
Kambiz Bahaadinbeigy and Kanagasingam Yogesan
1.1Introduction
Teleophthalmology is a branch of telemedicine that delivers eye care through digital medical equipment and telecommunications technology [1]. It does this through either a store-and-forward method or real-time communication and so enables doctors to attend to patients in remote areas [2]. It has been of increasing interest to researchers in the field of telemedicine over the last decade. This may have been due to the significance and prevalence of eye diseases, as well as a lack of specialists interested in working in remote areas.
A simple search for teleophthalmological research via the Medline database yielded hundreds of results with varying aims and objectives. There had been a significant increase in the research over the past decade, and this made summarising the papers challenging.
K. Bahaadinbeigy
Australian e-Health Research Centre,
Commonwealth Scientific Industrial
Research Organisation (CSIRO),
65 Brockway Road, Floreat,
WA 6014, Australia
K. Yogesan ( )
Ocular Health Research Group, Australian e-Health Research Centre,
CSIRO, 65 Brockway Road, Floreat, WA 6009, Australia e-mail: kan063@csiro.au
Although the studies possessed diverse aims and objectives, most focused on a particular eye problem, such as DR, glaucoma and adnexal disease. For instance, some of the projects questioned the feasibility of a particular type of teleophthalmological system for the screening of DR. Others concentrated on issues of cost and patient satisfaction. Whatever their main aims, each article took one or more eye diseases as its central theme.
The question of what eye problems had been of interest to date is important. Regardless of design or conclusions, each paper was proof of the field’s increasing relevance. But what were the strengths and weaknesses of the teleophthalmological publications in terms of focusing on different types of eye problems? In other words, having considered the wide variety of eye disease which can be consulted through a telemedicine system, which area has been more of interest for researchers?
There were also other important questions. For example, the type of telemedicine used in teleophthalmological projects (pre-recorded or real time) would have been of interest to eye care specialists.
Finally, the general conclusions made by the studies were also very significant. Were they positive, thus encouraging others to pursue the study, research and development of teleophthalmology?
This chapter discusses the findings of a systematic literature review of published papers that have documented teleophthalmological projects and been indexed by major bibliographic databases.
K. Yogesan et al. (eds.), Digital Teleretinal Screening, |
3 |
DOI 10.1007/978-3-642-25810-7_1, © Springer-Verlag Berlin Heidelberg 2012 |
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