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Digital Teleretinal Screening

Kanagasingam Yogesan

Leonard Goldschmidt • Jorge Cuadros

Editors

Digital Teleretinal

Screening

Teleophthalmology in Practice

Editors

 

Prof. Kanagasingam Yogesan

Dr. Jorge Cuadros

Ocular Health Research Group

School of Optometry

Australian e-Health Research Centre

University of California

CSIRO

Berkeley, CA

Floreat, WA

USA

Australia

 

Dr. Leonard Goldschmidt

 

Ophthalmology Lead, Diabetic

 

Teleretinal Screening Program

 

United States Department of Veterans

 

Affairs

 

Palo Alto Health Care System

 

Palo Alto, CA

 

USA

 

ISBN 978-3-642-25809-1 e-ISBN 978-3-642-25810-7 DOI 10.1007/978-3-642-25810-7

Springer Heidelberg New York Dordrecht London

Library of Congress Control Number: 2012934819

© Springer-Verlag Berlin Heidelberg 2012

This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. Exempted from this legal reservation are brief excerpts in connection with reviews or scholarly analysis or material supplied specifically for the purpose of being entered and executed on a computer system, for exclusive use by the purchaser of the work. Duplication of this publication or parts thereof is permitted only under the provisions of the Copyright Law of the Publisher’s location, in its current version, and permission for use must always be obtained from Springer. Permissions for use may be obtained through RightsLink at the Copyright Clearance Center. Violations are liable to prosecution under the respective Copyright Law.

The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use.

While the advice and information in this book are believed to be true and accurate at the date of publication, neither the authors nor the editors nor the publisher can accept any legal responsibility for any errors or omissions that may be made. The publisher makes no warranty, express or implied, with respect to the material contained herein.

Printed on acid-free paper

Springer is part of Springer Science+Business Media (www.springer.com)

Foreword

Drs. Kanagasingam Yogesan, Leonard Goldschmidt, and Jorge Cuadros have again edited a very useful text on the emerging discipline of ophthalmic telehealth. It builds on the progress demonstrated by the contributors from their first volume of Teleophthalmology, published in 2006. In the intervening 5 years, much has happened in this field to validate and expand the original reports. As we look for ways to improve the quality and also the cost-effectiveness of health care, the contributions in this new volume make it clear that teleophthalmology will have an important role to play. The reports contributed to this new volume highlight advances in technology and clinical process, demonstrating that teleophthalmology is already improving access to eye care for many thousands of people on a daily basis.

As well-recognized authorities and active participants in seminal projects in this field nationally and internationally, the editors are particularly well suited to shed light on how this field is progressing. With contributions from a number of influential thinkers and practitioners in this field, there are excellent individual chapters on screening and automated reading for diabetic retinopathy, retinopathy of prematurity, and ocular tumors. Also present in this volume are reports on screening for macular degeneration and glaucoma, although their limited number reflects the nascent state of the art in these subspecialties and the early formation of validated studies and standards. Clinicians, house officers, and medical students interested in this area will find this to be a valuable resource.

Mark S. Blumenkranz M.D.

Professor and Chairman

Byers Eye Institute at Stanford,

Stanford Medical Centre &

Stanford School of Medicine

v

Preface

Since publishing our first book on teleophthalmology in 2006, we have seen the field expand rapidly to encompass many ophthalmic applications. There has been a significant increase in peer-reviewed studies related to teleophthalmology from around the world. We have noted that more than 40% of such published articles are related to remote diagnosis of retinal diseases such as diabetic retinopathy. Therefore, in an effort to summarize and closely examine current thinking, we focus predominantly in this issue on telemedicine use for retinal imaging of disease, with some attention to glaucoma screening.

In the past several years, telemedicine screening for diabetic retinopathy has been well established in many countries and programs, with much supporting cost benefit analysis, publication of technical details, and demonstration of improved clinical outcomes and patient access. However, there are ongoing limitations related to fee-for-service models, as well as the cost of imaging and medical record technologies, which restricts the expansion of diabetic retinopathy screening. Important conditions such as retinopathy of prematurity, glaucomaandmaculardegenerationarealsobeingdiagnosedwithteleophthalmology techniques; however, protocols, validation, and technical standards are less developed.

We have organized this book into two main sections: (1) current state of the art and future trends and (2) telemedicine applications and global experience. The first section includes a review, which examines published work related to teleretinal imaging and its outcomes. Also included are reviews of validation studies on some of the newer applications of retinal imaging such as those for the detection of systemic diseases, including cardiovascular and neurological conditions. Such a volume as ours would not be complete without a discussion of the emerging applications related to automated grading of retinal images. Such computer-aided analysis is expected to greatly assist trained image readers as well as to support more widespread patient screening. The improvement of such automated image analysis may represent a pivotal moment in telemedicine, as there is still a great need for enhanced accurate screening and disease due to dramatic increases in the incidence of diabetes and diseases related to aging. Technological improvements also move relentlessly forward, and there are chapters devoted to examining new retinal imaging techniques with lower cost cameras.

vii

viii

Preface

 

 

Section two is divided into teleophthalmology studies related to projects involving both adult and pediatric patients. The former section encompasses remote screening imaging for diabetic retinopathy, glaucoma and AMD. The pediatric section examines the use of this technology for the care of those infants at risk for retinopathy of prematurity and those with retinoblastoma. This section also presents studies from around the world which discuss the unique challenges of implementing teleretinal imaging programs. The editors believe that the lessons of such studies will be pertinent to others with similar challenges.

We have attempted to design this book in a way that will benefit healthcare providers at all levels, including primary care physicians, ophthalmologists and optometrists, as well as nursing professionals who are planning to use telemedicine for the diagnosis of ocular diseases affecting the retina and optic nerve. Taking care to provide the best telemedicine applications worldwide that we were aware of, we understand that there is always an opportunity in programs for improvement in process, technical ease of use, and patient experience. Comments and feedback from our readers are welcome that may further improve our efforts in the future. Studies related to diagnosing glaucoma remotely (teleglaucoma) as well as age-related macular degeneration (AMD) are in a relatively early stage, and we wish to introduce these topics to a wider audience.

We are greatly indebted to the authors who contributed to this book by sharing their experience with our readers, and we make every effort to keep the information clear and useful. We would like to thank them American Telemedicine Association for allowing us to include their Telehealth Practice Recommendations for Diabetic Retinopathy. This report, which forms the basis of many programs, may be considered as a well-developed guideline for diabetic retinopathy screening, and it has the potential to form the basis for program development and thinking in our readers.

We owe great thanks to Drs. Mark Blumenkranz and Ian Constable, mentors for many of us in the field, and we are grateful for their contributions to the book. Our overriding goal is to see this technology and health-care model educate those who would like to establish and improve teleophthalmology in order to prevent needless blindness around the world. We are proud to play a small role in this effort by bringing the lessons in this volume to a wider

audience.

Kanagasingam Yogesan

Leonard Goldschmidt

Jorge Cuadros