Ординатура / Офтальмология / Английские материалы / Diabetic Retinopathy_Shamsul Ola_2012

DIABETIC RETINOPATHY

Edited by Mohammad Shamsul Ola

Diabetic Retinopathy

Edited by Mohammad Shamsul Ola

Published by InTech

Janeza Trdine 9, 51000 Rijeka, Croatia

Copyright © 2012 InTech

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Statements and opinions expressed in the chapters are these of the individual contributors and not necessarily those of the editors or publisher. No responsibility is accepted for the accuracy of information contained in the published chapters. The publisher assumes no responsibility for any damage or injury to persons or property arising out of the use of any materials, instructions, methods or ideas contained in the book.

Publishing Process Manager Ivana Zec

Technical Editor Teodora Smiljanic

Cover Designer InTech Design Team

First published February, 2012

Printed in Croatia

A free online edition of this book is available at www.intechopen.com Additional hard copies can be obtained from orders@intechweb.org

Diabetic Retinopathy, Edited by Mohammad Shamsul Ola p. cm.

ISBN 978-953-51-0044-7

Contents

VI Contents

Chapter 8 Immunological Risk Factors for the Development and Progression of Diabetic Retinopathy 137

Katarzyna Zorena, Dorota Raczyńska, and Krystyna Raczyńska

Gerardo Escobedo, Kalpana Parvathaneni,

Brandi S. Betts and Andrew T.C. Tsin

Preface

During the past few decades great progress has been made in our understanding of pathophysiology, management and treatment of diabetic retinopathy. However, diabetic retinopathy still remains the leading cause of blindness among working adults worldwide. The goal of the book is to provide an update on latest developments in the understanding of pathophysiology of the disease, diagnosis and recent treatments strategies for physicians, ophthalmologists, researchers and medical students.

This book covers topics ranging from pathophysiology to clinical aspects of DR and emerging treatments and concepts in diabetic retinopathy. The first section serves as a description of current understanding of the cellular and molecular mechanism of pathophysiology of diabetic retinopathy, in order to develop possible therapeutic strategies. The second section describes general pathogenic concepts of inflammation and angiogenesis. The third section describes clinical aspects and modern diagnostic features. The fourth part discusses recent concepts and emerging treatment strategies relating to the management of diabetic retinopathy. The originality and style of the text by authors have been kept intact, although some aspects overlap in more than one chapter which is justified by their unique approach and interpretation.

I am very grateful to all the contributors who have worked very hard to make this book a reality. I would also like to thank staff at INTECH, especially Mr. Igor Babic, Publishing Manager and the technical team who did a great job working together on this book. I hope this book will provide a resource for advancing understanding, as well as improving diagnosis and treatment strategies in the effort to help numerous patients who suffer from DR and are threatened by visual loss.

Mohammad Shamsul Ola

Department of Ophthalmology, College of Medicine, King Saud University, Riyadh, Kingdom of Saudi Arabia