Index

A

ABO-matched corneas, 101

Acanthamoeba, 56 Amblyopia therapy, 115 Aminoglycosides, 10, 28 Amiodarone, 61 Amniotic membrane, 67 Angiogenic privilege, 73 Aniridia, 71

Anterior synechia, 112 Anterior vitrectomy, 114

Antisense oligonucleotides, 85–86 Anti-VEGFs, 72, 82–85

Aspergillus fungi, 56

Atopic keratoconjunctivitis, 61 Avascular tissues, 74

Avellino macular central dystrophy, 58

B

Besifloxacin, 29–30, 33

Bevazicumab, 82–85

Bowman’s layer dystrophies, 58

Bowman’s membrane, 55

Brittle cornea syndrome, 49

C

Carbol fuschin-based stains (Kinyoun (cold)), 5–6

Central cloudy dystrophy of François, 58 Central mosaic, 58

Cephalosporins, 29

CHED. See Congenital hereditary endothelial dystrophy (CHED)

Chemical burns, 71, 76 Chloroquine, 61 Ciproflloxacin, 25, 26

Collaborative corneal transplantation study, 75

Collagen cross-linking, 37 Collagen genes, 43–44 Confocal microscopy, 78

Congenital corneal opacities, 109 Congenital glaucoma, 108

Congenital hereditary endothelial dystrophy (CHED), 108

Congenital hereditary stromal dystrophy, 108 Contact lens-induced corneal changes, 61 Contact lens wear, 22, 71

Corneal angiogenesis, 71

Corneal angiogenic privilege, 71, 74 Corneal cross-linking, 14

Corneal dystrophies, 57–59 Corneal endothelium, 93 Corneal epithelium, 55 Corneal graft rejection, 77–80 Corneal grafts, 66–68 Corneal preservation, 91 Corneal refractive surgery, 65 Corneal rings, 66

Corneal rupture, 49 Corneal surgery, 56, 61 Corneal wound healing, 56

Corneoscleral button, 93, 97–101 Corticosteroids, 13 Cyclosporine, 82

Cylokernlin, 37

D

DALK. See Deep anterior lamellar keraloplasty (DALK)

Debridement, 13

Deep anterior lamellar keraloplasty (DALK), 66, 77, 118

Deep lamellar keratoplasty, 61 Dermoid, 108

Descemet membrane, 55, 56

Descemet’s membrane automated endothelial keratoplasty (DMAEK), 103

Descemet’s membrane endothelial keratoplasty (DMEK), 101, 103

Descemet stripping automated endothelial keratoplasty (DSAEK), 101, 102

Descemet stripping endothelial keratoplasty (DSEK), 2, 61, 101, 118

DMAEK. See Descemet’s membrane automated endothelial keratoplasty (DMAEK)

DMEK. See Descemet’s membrane endothelial keratoplasty (DMEK)

DNA microarray, 9 DNA sequencing, 9 Donor eye, 96–97 Donor tissue, 93 Dry eye, 61, 80

DSAEK. See Descemet stripping automated endothelial keratoplasty (DSAEK)

DSEK. See Descemet stripping endothelial keratoplasty (DSEK)

E

EBAA. See Eye Bank Association of America (EBAA)

EBMD. See Epithelial basement membrane (EBMD)

Endophthalmitis, 94 Endothelial cell counts, 112 Endothelial graft, 66 Enucleation, 95

Epithelial basement membrane (EBMD), 58 European Eye Bank Association (EEBA), 92 Exposure keratopathy, 108

Eye bank, 92

Eye Bank Association of America (EBAA), 92

F

Fabry’s disease, 61

Femtosecond laser-assisted flaps, 65 Femtosecond laser cutting, 102–103 FISH. See Fluorescent in situ hybridization

(FISH) Flieringa ring, 113

Fluorescent in situ hybridization (FISH), 9 Fluorescent stains, 6

Fluoroquinolones, 10, 28, 29 Fuch’s endothelial dystrophy, 49, 59

Fusarium, 56

G

Genetic mapping, 44–47

Glaucoma, 108, 116

Glycopeptides, 29

Graft failure, 108, 117

Graft rejection, 116–117

Granular, 58

GS101, 82

H

Hemangiogenesis, 75 Herpes infection, 100 Herpes simplex keratitis, 21 Herpetic keratitis, 74

High-risk keratoplasty, 71, 72, 77 HLA-matched cornea, 101 Hypothermic storage, 97–98 Hypoxia (contact lens), 76

I

Immune reflex arc, 73 Immune rejection(s), 77, 108 Infant keratoplasty, 107 Infection, 1

Infectious keratitis, 56–57 Interface, 61

Interleukin 1, 43 Intracorneal rings, 65 Intraocular pressure, 110

Intraoperative lens extrusion, 113

In vivo confocal microscopy (IVCM), 53–54, 81

In vivo multiphoton imaging, 81 IVCM. See In vivo confocal microscopy

(IVCM)

K

Keratitis, 71, 76, 108

Keratoconus, 37, 49, 61, 66, 108

Keratocyte, 56

Keratoglobus, 49

L

Lamellar endothelial keratoplasty, 92 LASEK, 2

Laser in situ keratomileusis, 65 LASIK, 2, 59, 65

Lensectomy, 114

Lifting of the flap, 14 Light microscopy, 100 Linezolid, 30, 33 Linkage studies, 46 Liposomes, 10 Lowenstein-Jensen agar, 7

Low-risk keratoplasty, 72, 76 Lymphangiogenesis, 75 Lymphangiogenic privilege, 72 Lymphatic vessels, 71, 79, 81

M

Macrolides, 10 Marfan syndrome, 61

Mc Carey and Kaufman, 95 Media(solid) Chocolate Agar Sheep

Blood Agar Lowenstein Jensen Media, 5

Meesmanndystrophy, 37, 58 Mendelian disorders, 47 Meropenem, 30–31, 33 Metabolic disorders, 108 Microbiological safety, 97–100 Microsatellite markers, 45 Moist chamber storage, 96–97 Molecular tests, 8

Mutational screening, 38–42

Mycobacteria chelonae complex, 4 Mycobacterial keratitis, 1

Mycobacterium M. abscessus, 4 M.asiaticum, 2

M.avium complex, 2 M.chelonae, 3

M. chelonae, 4 M.flavescens, 2 M.fortuitum, 3 M. fortuitum, 4 M.gordonae, 2

M.immnogenum, 3

M.immunogenum, 3 M. immunogenum, 4 M. leprae, 4 M.marinum, 2

M.nonchromogenicum, 2 M.skulgai, 4 M.smegmatis, 3 M.szulgai, 2

M.terrae, 2, 4

M.triviale, 2

M. tuberculosis, 4, 6

N

Nanoparticles, 13 Nephropathic cystinosis, 61

Neurotrophic keratopathy, 21, 87 Nucleic acid hybridization probes, 8

O

OCT. See Optical coherence tomography (OCT) Ocular surface disease, 22

Optical coherence tomography (OCT), 53 Optical correction, 115

Organ culture, 99–101

P

PCR. See Polymerase chain reaction (PCR) Pegaptanib, 82–85

Penetrating keratoplasty, 14, 67, 94, 107 Peripheral iridectomy, 114

Peters’ anomaly, 108

PFGE. See Pulse field gel electrophoresis (PFGE)

Phakic implants, 66 Phakic intraocular lens, 67

Polymerase chain reaction (PCR), 24 Posterior capsulotomy, 114 Posterior polymorphous corneal

dystrophy-1, 38, 59, 108 Povidone–iodine solution, 94 Pre-cutting, 101

Primary open-angle glaucoma, 47 PRK, 59

Pseudomonas aeruginosa, 22, 25, 28, 32 Pulse field gel electrophoresis (PFGE), 9

R

Ranibizumab, 82–85

Refractive surgery, 56, 59–60, 65–66 Reis-Bucklers dystrophy, 58, 59 Resistance, 25–26, 33

Retinitis pigmentosa, 47 Rotational autografts, 118 Runyon classification, 4

S

Schnyder dystrophies, 58, 59

Sclerocornea, 108

Scrapes, 24

Sjogrens syndrome, 21