Ординатура / Офтальмология / Английские материалы / Color Atlas of Herpetic Eye Disease A Practical Guide to Clinical Management_Sundmacher_2009

This book is more than an atlas and a text. It has what clinicians want most: experience.

Actual case examples are analyzed by a specialist who has arguably treated more patients with ocular herpes than any other ophthalmologist. Not merely an inventory of viral keratitis, this sourcebook explains the ins and outs of infection and inflammation due to herpes simplex virus, varicella-zoster virus and other herpes viruses.

Herpetic eye disease needs a descriptive vocabulary, and the author provides a sensible classification. His distinctive terminology updates outmoded jargon, creating a new norm.

Professor Sundmacher communicates with clarity, continuity and style.

The book’s strength is in its details. Therapeutic decisionmaking is based on clinical research, often the author’s own pioneering trials. For medical and surgical dilemmas, practicebased advice springs from a pragmatic explanation of virology, immunology and wound healing.

The proficiency and scope of this authoritative resource leads me to rephrase a century-old maxim: ‘To know herpes is to know ophthalmology.’

Kirk R. Wilhelmus, MD PhD

Houston, Texas USA

It is a pleasure to write a foreword for this beautiful atlas of ocular disease caused by herpes viruses. I first met Professor Rainer Sundmacher in Freiburg many years ago when he set up an inspirational meeting on these viruses. Since that time in the early 1980s, he has worked tirelessly on the management of viral disease of the external eye. Virus research has exploded in recent years, and in particular great strides have been made in the development of antiviral therapy. It is therefore an appropriate time to produce an atlas of these diseases, which can cause serious visual loss. The book also provides detailed advice on treatment and therapy.

It is the external disease caused by herpes simplex and varicella zoster virus that is most frequently seen by ophthalmologists. This book highlights many of the difficult problems that are encountered in the diagnosis and management of these viruses. The detailed and vivid photographs illustrate the main

features of these viruses, and the analysis of each photograph provides unique insights in a clinical setting. Such insights will be useful to those involved in the management of viral diseases of the eye. There are uplifting accounts of clinical treatments that can lead to successful outcomes, although at the same time caution is urged, since these treatments can cause damage to the eye if not carefully monitored by clinicians. This volume will enable those who are not experts in corneal and external disease to recognize conditions that may be foreign or new to them, and thus can be recommended to benefit A&E departments, where there is no ophthalmological immediate supervision. On the other hand, the atlas will be valuable to both trainees and consultants because of the considerable expertise and experience that the authors have gathered in their clinical careers.

David Easty, MD FRCS FRCOphth.

Professor Emeritus of Ophthalmology

University of Bristol, UK

Firstly, I owe thanks to Professor Reiner Thomssen, virologist in Göttingen, who inspired my interest in this field, and who was really disappointed when I had to leave him to start a clinical career in ophthalmology under the supervision of Professor Günter Mackensen in Freiburg. I remember Günter Mackensen with warmest respect for trusting my abilities and responsibility as a young resident and for his lasting interest in all my herpes and keratoplasty projects. These could not have been performed without numerous co-workers, all of whom deserve thanks. Their names are documented in the publications of our group. Especially important help came from the virologist Dieter Neumann-Haefelin and Annegret Mattes, who were responsible for the virological part of my Freiburg studies, while the medical photographer H. Preuninger supplied an impressive basis of thousands of slides from my herpes patients. I look back with warmest memories on the long series of experimental and clinical interferon studies. They would not have been possible without the trustful and generous help of Professor Kari Cantell, from Helsinki, the only person worldwide who was able to supply highly purified leukocyte interferon for clinical studies.

In regards to my research done in Düsseldorf, I would like to especially thank Thomas Reinhard, who made the most valuable contributions in the fields of keratoplasty, secondary glaucoma, and systemic immunotherapy after keratoplasty, to which Alexander Reis added important experimental work. The clinical slide collection was further augmented by Helen Baseler, Gerlinde Westphal, and Kerstin Bisgiel.

My research work on herpes would have been impossible without the input from the many publications worldwide and from personal contacts and discussions with international herpes researchers. As I cannot even roughly name the most im-

portant publications of my colleagues, I would like to thank – pars pro toto – some of the attendees of the First International Symposium on Herpetic Eye Diseases, held in Freiburg in 1980. I have learned a great deal from all of them and owe them a lot: J. R. Baringer, O. P. van Bijsterveld, K. Cantell, E. De Clercq, J. Colin, L. M. T. Collum, D. J. Coster, D. L. Easty, M. G. Falcon, C. S. Foster, B. R. Jones, H. E. Kaufman, R. J. Marsh, P. C. Maudgal, J. McGill, T. C. Merigan, G. O. H. Naumann, A. B. Nesburn, J. O. Oh, W. H. Prusoff, H. Shiota, G. Smolin, H. M. J. Völker-Dieben, G. O. Waring III, and K. R. Wilhelmus.

This atlas would not have been finished without the constant pressure of my colleagues attending the herpes, cornea, and keratoplasty courses, which I have been teaching over the last decades. Whether they are really to be thanked for this pressure, must be left to the judgement of the reader.

I am grateful to Hartmut Hengel for the introductory virological chapter, to Johannes Stammen for help with the chapter on anterior segment CMV disease, to Thomas Reinhard for his work on presumed EBV disease, and to Lutz Hansen for the well-illustrated chapter on posterior segment diseases caused by herpes viruses.

I thank my family, whose continuous love and support for my professional work made this possible.

Finally, it is a pleasure to thank Springer and staff, especially Marion Philipp and Martina Himberger and Nadja Kroke for their excellent editing work.

1.2Virus Taxonomy

1.4Distinct Features

2.6Interstitial

2.8HSV Trabeculitis

2.12Clinically Manifest

2.14Intraocular Surgery