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see also Chapter 8, Constricted fields after herniation).

Diagnosis: Shunt malfunction in the absence of ventriculomegaly

Tip: The dorsal midbrain syndrome is an important and early sign of shunt failure and may occur even in the absence of radiographic changes.

FURTHER READING

Vitamin B12 deficiency

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K. Juhasz-Pocsine, S. A. Rudnicki, R. L. Archer, S. I. Harik, Neurologic complications of gastric bypass surgery for morbid obesity. Neurology, 68 (2007), 1843–50.

J.Lindenbaum, E. B. Healton, D. C. Savage et al., Neuropsychiatric disorders caused by cobalamin deficiency in the absence of anemia or macrocytosis. N Engl J Med, 318

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J.F. Rizzo, Adenosine triphosphate deficiency: a genre of optic neuropathy. Neurology, 45 (1995), 11–16.

Digoxin toxicity

V.P. Butler Jr., J. G. Odel, E. Rath et al., Digitalis-induced visual disturbances with therapeutic serum digitalis con-

centrations. Ann Intern Med, 123 (1995), 676–80.

H. A. Horst, K. D. Kolenda, G. Duncker, F. Schenck, H. Lottler, Color vision deficiencies induced by subtoxic and toxic digoxin and digitoxin serum levels. Med Klin, 83 (1988), 541–7.

J.R. Piltz, C. Wertenbaker, S. E. Lance, T. Slamovits, H. F. Leeper, Digoxin toxicity: recognizing the varied visual presentations. J Clin Neuroophthalmol, 13 (1993), 275–

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R.G. Weleber, W. T. Shults, Digoxin retinal toxicity: clinical and electrophysiologic evaluation of a cone dysfunction syndrome. Arch Ophthalmol, 99 (1981), 1568– 72.

Chapter 10: Over-reliance on negative test results

177

 

 

 

Myasthenia

K. C. Golnik, R. Pena, A. G. Lee, E. R. Eggenberger, An ice test for the diagnosis of myasthenia gravis. Ophthalmology, 106 (1999), 1282–6.

E. B. Ing, S. Y. Ing, T. Ing, J. A. Ramocki, The complication rate of edrophonium testing for suspected myasthenia gravis. Can J Ophthalmol, 35 (2000), 141–4.

K.C. Kubis, H. V. Danesh-Meyer, P. J. Savino, R. C. Sergott, The ice test versus the rest test in myasthenia gravis. Ophthalmology, 107 (2000), 1995–8.

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Aneurysmal third nerve palsy

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One-and-a-half syndrome

M. R. Hanson, M. A. Hamid, R. L. Tomsak, S. S. Chou, R. J. Leigh, Selective saccadic palsy caused by pontine lesions: clinical, physiological and pathological correlations. Ann Neurol, 20 (1986), 209–17.

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178Chapter 10: Over-reliance on negative test results

Cortical visual loss with negative neuro-imaging

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Eggenberger, Homonymous visual field defects in patients without corresponding structural lesions on neuroimaging. J Neuroophthalmol, 20 (2000), 92–6.

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Skull base tumors with negative imaging

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Shunt failure with negative neuro-imaging

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