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Ординатура / Офтальмология / Английские материалы / Clinical Ocular Pharmacology 5th edition_Bartlett, Jaanus_2008

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Index

777

Imidazole derivative, 247, 248t, 249

Infection—cont’d

Injectable anesthetic, 86-87, 87t

 

Imipramine, 721t

canalicular, 433

Injection

 

Immune inflammation, acute and

of conjunctiva, 444-463. See also

conjunctival, 452

 

chronic, 237f

Conjunctivitis

epithelial microcysts and, 543

 

Immune system

corticosteroid increasing, 232

local infiltrative, 324

 

conjunctivitis and, 444

dacryoadenitis, 424, 424f

peribulbar, 49-50, 49b, 49f

 

in thyroid disease, 645

fungal. See Fungal infection

retrobulbar, 49, 49b

 

Immunization, varicella zoster, 396

meibomian gland, 386-387, 387f

steroid, for chalazion, 390

 

Immunocompromised patient, 396

of meibomian gland, 386-389, 387f

subconjunctival, 47-48, 49f

 

Immunoglobulin therapy for cicatricial

optic neuropathy in, 366-367

sub-Tenon’s, 49, 49f

 

pemphigoid, 468

of posterior lid margin, 386-389, 387f,

Injury. See Trauma

 

Immunologic disease, scleritis with,

388f

Innervation. See also Nerve entries

 

577b

postoperative, prevention of, 601

adrenergic, 113-114

 

Immunology, allergic, 245-249, 549-550

in scleritis, 584

cholinergic, 125, 126f

 

cell-mediated response in, 247

scleritis with, 577b

Inorganic essential minerals, 295-301,

treatment options and, 247

uveitis with, 588b

296t

 

type I hypersensitivity in, 245-247,

viral. See Viral infection

Insert, artificial tear, 271-272, 272f

 

246f, 246t

Inferior rectus muscle, 649

Instillation of solution, 40-42, 41b, 41f, 42f

Immunomodulatory agent, for tear

Infestation, eyelash, 397-399, 398

Insurance, glaucoma treatment and, 696

augmentation, 429

Infiltrating basal cell carcinoma, 403

Interferon, 595

 

Immunosuppression

Infiltrative event

Intermediate uveitis

 

in allergic disease, 550

in bacterial keratitis, 519-520, 519f, 519t

complications of, 596-597

 

in myasthenia gravis, 375-376

contact lens-related, 538-542, 540f, 544f

description of, 587

 

for necrotizing scleritis, 585

Infiltrative injection, local, 324

diagnosis of, 591-592

 

for ocular cicatricial pemphigoid, 468

Infiltrative keratitis, 540t

Internal limiting membrane, 306

 

for polyarteritis nodosa, 472

Infiltrative optic neuropathy, 366-367

Interstitial keratitis, 515-517, 516b, 516t

in scleritis, 584, 585

Infiltrative thyroid-related orbitopathy,

Intolerance to apraclonidine, 155

 

for uveitis, 595-596

652

Intracameral administration, 50

 

Immunotherapy in myasthenia gravis, 376

Inflammation

Intracanalicular plug, 273t

 

Impaired vision from dilation, 76

acute and chronic immune, 237f

Intracranial hypertension, drug-induced,

Imuran, 595

after cataract surgery, 602

739-740, 739t

 

Incision of eyelid, 410-412, 411f

canalicular, 433

tetracyclines and, 190

 

Inclusion conjunctivitis, 456-457, 457f

conjunctival, 439-440, 474-478

Intracranial lesion, myasthenia gravis

Indinavir, 207t

in phlyctenulosis, 474-475, 475f

and, 375

 

Indirect ophthalmoscopy, 676

in pinguecula, 476, 476f

Intraocular lens dislocation, 612-613, 613f

Indocid, 236t

pterygium and, 477-478, 477f

Intraocular pressure

 

Indocin

in superior limbic

adverse drug effects on, 7t, 722-725,

adverse effects of, 751t

keratoconjunctivitis, 475-476,

722b, 723t

 

for uveitis, 595

476f

atropine and, 129

 

Indocyanine green, 291-292, 291f

cyclosporine A as immunomodulator

cataract surgery and, 603, 608

 

Indocyanine green angiography, 619-620

of, 236-242

corticosteroid increasing, 229-232, 241f

Indomethacin, 102t

dry eye and, 264-265

drugs for. See Hypotensive drug

 

adverse effects of

of eyelid, 568, 570

hyphema and, 692

 

on cornea, 709-710

in chalazion, 390-391

measurement of, 671-674, 673b

 

retinal, 730

in external hordeolum, 389, 389f

in retinal vein occlusion, 634

 

brimonidine and, 235

in internal hordeolum, 389-390, 390f

tropicamide and, 135-136

 

formulations of, 236t

lacrimal gland and, 416

Intravitreal implant, ganciclovir, 34, 36

for uveitis, 595

postoperative, 228

Intravitreal injection, 50-51, 51f

 

Infant

in staphylococcal blepharitis, 383f

of corticosteroid implant, 309

 

conjunctival flora in, 438

in thyroid disease, 645, 648

of ranibizumab and bevacizumab, 308

cycloplegic refraction in, 343, 344

in uveitis, 588

of triamcinolone acetonide, 308-309

epiphora in, 429-430

Inflammatory cytokine, 265

Invirase, 207t

 

esotropia in, 667-668

Inflammatory glaucoma, steroid-

Iontophoresis, 94

 

maternal myasthenia gravis and, 373

induced, 596

Ipratropium bromide, 718

 

pupil dilation in, 334-335

Inflammatory response, 233

Iproclozide, 690t

 

Infection. See also Antibacterial drug;

Infliximab

Iproniazid, 690t

 

Bacterial entries; specific infection

adverse effects of, 716t, 717

Iridectomy, 336-337, 337f

 

of anterior lid margin, 381-386, 383f,

for uveitis, 595

Iridocyclitis, 587. See also Anterior uveitis

385f, 386f

Informed consent

rimexolone for, 229

 

of anterior margin of eyelid, 382-384,

alternatives to drug therapy and, 69

Iris

 

383f

disclosure in, 65-66, 66b

angiography of, 287-288

 

bacteria causing, 177

documentation in, 70

in anterior uveitis, 590

 

778 Index

Iris—cont’d injury to, 362

pilocarpine for, 168 structure of, 22

Iritis, 587. See also Anterior uveitis Irradiation, orbital, 660

Irrigating system, 47-48, 48f Irritant contact dermatitis, 570-571

Ischemia in neovascular glaucoma, 693 Isocarboxazid, 690, 690t

Isoenzyme II, 164

Isopto, 127t, 688t

Isopto Atropine Ophthalmic, 127t Isotretinoin, adverse effects of, 751t

on conjunctiva, 711-713, 712t on cornea, 710-711

on eyelid, 711-713, 712t reduced tear production, 714 retinal, 733-734

Istalol, 146t

Itraconazole, 208, 209t, 211t, 213, 213t of Acanthamoeba, 216t

Ivermectin, 399

J

Jimson weed, 361-362, 741 Jones test, 431-432 Juvenile arthritis

calcific band keratopathy in, 494 uveitis in, 599

K

Kaletra, 207t

Keflex, 184t

Kefurox, 184t Kefzol, 184t

Kenalog, intravitreal, 35t Keratectomy, superficial

in calcific band keratopathy, 495 in recurrent corneal erosion, 507

Keratic precipitate, 587 Keratinization, epidermal, 271 Keratinized epithelium, 480 Keratitis

Acanthamoeba, 215, 216t, 217, 536538, 537f, 538t

amphotericin B for, 208 antibacterial drugs for, 176t bacterial, 514-525

corneal infiltrative events versus, 519t

infiltrative events in, 519-520, 519f, 519t

interstitial, 515-517, 516b, 516t phlyctenular keratoconjunctivitis,

517-518, 518f

superficial punctate, 514-515, 514f ulcers and, 520-525, 521f, 521t, 522f

contact lens-related, 540t epithelial, acyclovir for, 201 fluoroquinolones for, 195 fungal, 534-536, 535f

Keratitis—cont’d glaucoma with, 694

in herpes zoster ophthalmicus, 533 non-Acanthamoeba, 217 Thygeson’s superficial punctate,

241-242

toxic, 513-514, 514f viral, 525-534

epidemic keratoconjunctivitis and, 525-527, 526f

herpes simplex, 527-530, 528f, 530f

herpes zoster, 530-533, 531f, 531t, 532f

Thygeson’s superficial punctate, 533-534

Keratoconjunctivitis

atopic, 557t, 559t, 567-568, 567f cyclosporine A for, 241 epidemic, 452, 452f, 453t

nontuberculous phlyctenular, 190 phlyctenular, 517-518, 518f superior limbic, 475-476, 476f vernal, 557t, 559t, 564-566, 565f

mast cell stabilizers for, 255 Keratoconjunctivitis sicca

aqueous deficiency and, 264 non-Sjögren’s, 425-426

in rosacea, 389

Keratoconus, 490, 491f, 492-493, 492f Keratoderma blennorrhagica, 473, 473f Keratolysis, diclofenac and, 235 Keratopathy

bullous, 493-494, 493f calcific band, 494-496, 495f chloroquine and, 705-706 exposure, 507-509

in thyroid disease, 649-650, 650f Keratoplasty

in Fuchs’ dystrophy, 490f penetrating

in fungal keratitis, 536 in trauma, 503-504

Keratosis, actinic, 405, 405f Ketoconazole, 208, 211t, 213t Ketoprofen, 102t

Ketorolac, 102t, 235

for allergic disease, 259, 554t for corneal abrasion, 496

in cystoid macular, 633 in episcleritis, 578 formulations of, 236t

for pseudophakic cystoid macular edema, 614

in recurrent corneal erosion, 507 for seasonal conjunctivitis, 561

Ketotifen, 257, 258t, 553t

in seasonal conjunctivitis, 561 Kinetics, diffusion, 26-27

Klebsiella aminoglycosides for, 187

chronic conjunctivitis and, 451

Klebsiella—cont’d corneal ulcer and, 520

infections caused by, 178t

L

Laboratory testing

for conjunctivitis, 440-444 culture in, 440-442 indications for, 440, 441b

smears and scrapings in, 442-444, 443t

for scleritis, 582, 583t

for uveitis, 597-599, 598t, 599b Laceration

conjunctival, 479-480 corneal, ointment for, 44

lamellar, 502-504-502f, 503f, 504f Lacri-Lube, 272t

Lacrimal gland. See also Lacrimal system anatomy and physiology of, 415 blepharospasm and, 377

disorders of, 424 evaluation of, 423-424, 424f innervation to, 125

tears and, 264

Lacrimal occlusive device, 273-274, 273f, 274f

Lacrimal system, 415-435

adverse drug effects on, 713-715, 714t anatomy and physiology of, 415-418,

416f

of distribution system, 417 of excretory system, 417-418

of secretary system, 415-417, 416f, 417f

disorder of

acquired dacryocystitis as, 433-434 of distribution system, 425

of drainage, 432-433

dry eye syndrome as, 425-429. See also Dry eye

of ocular surface, 424-425 evaluation of

of distribution system, 424 of dry eye patient, 424b

of lacrimal drainage system, 429432, 430f, 431f, 432f

of lacrimal gland, 423-424, 424f of ocular surface, 422-423, 423f patient history in, 418-419

of secretory system, 419-420

of tear film, 420-422, 420f, 421b, 422f, 422t, 423f

fluorescein sodium for evaluation of, 286

overview of, 415 Lacrisert, 271-272, 272f Lactation

homatropine and, 130 opioid and, 107 precautions for, 9-11 verteporfin and, 304

 

 

Index

779

Lagophthalmos, 406

Levobunolol, 150-151

Local anesthetic—cont’d

 

nocturnal, 508

formulations of, 146t

toxicity as, 90-91, 90f, 91f

 

Lamellar endothelial keratoplasty, 490f

for glaucoma, 689t

structure features as, 86f

 

Lamellar laceration, 502-504-502f, 503f,

Levocabastine, 254t, 255, 551t

topical, 87-90, 88t, 89f

 

504f

in seasonal conjunctivitis, 560

Local infiltrative injection, 324, 325-326,

Lamivudine, 206t

Levodopa, for blepharospasm, 377

326f

 

Landmark in gonioscopy, 333f

Levofloxacin, 194t, 195

Localized contact lens-related papillary

Langerhans cell, 438

for conjunctivitis, 449

conjunctivitis, 563

 

Laser, stromal puncture with, 506

formulations of, 186t

Lodine, 751t

 

Laser imaging in glaucoma, 679, 679t

for infectious conjunctivitis, 446

Lodoxamide, 255, 256t, 257, 553t

 

Laser in situ keratomileusis

in preseptal cellulitis, 391

in seasonal conjunctivitis, 561

 

cyclosporine A for, 265

Lexiva, 207t

in vernal keratoconjunctivitis, 566

dry eye after, 265

Liability, product, 78

Lomefloxacin, 194t

 

Laser surgery

Licorice, 741

Loop for foreign body removal, 499, 499f

iridectomy, 336-337, 337f

adverse effects of, 759t

Lopinavir, 207t

 

Laser surgery

Lid margin, 425

Loratadine, 250, 252t, 253, 552t

 

acetazolamide and, 161

Lid scrub, 45, 46t

for seasonal conjunctivitis, 561

 

apraclonidine and, 155

Lidocaine

Lotemax, 555t

 

brimonidine and, 157

injectable, 87t

Loteprednol, 554t

 

LASIK

intracameral administration of, 50

as antiallergy drug, 259

 

cyclosporine A for, 242

subcutaneous injection of, 327f

clinical uses of, 228-229

 

dry eye after, 265

Light reaction in anisocoria, 349, 351f

contact lens-related papillary

 

Latanoprost, 139-143, 687-688, 687t

Light sensitivity after pupil dilation, 339

conjunctivitis and, 564

 

brimonidine with, 156

Limbal conjunctival substantia propria,

for corneal ulcers, 525

 

clinical uses of, 140-141

438

in episcleritis, 578

 

contraindications to, 142

Limbal keratoconjunctivitis

formulations of, 227t

 

pharmacology of, 139-140, 140f

superior, 475-476, 476f

in seasonal conjunctivitis, 561

 

side effects of, 141-143, 141b, 142f

vernal, 565

for Thygeson’s superficial punctate

Lateral tarsorrhaphy, 427-428

Limbal phlyctenule, 474

keratitis, 534

 

Lattice type dystrophy, 485t

Limbal stem cell transplantation, 468-469

Lovastatin, 749t

 

Lavage for foreign body, 479f

Line

Low vision, 13-14, 13f-14f

 

Law, Fick’s, 25-26

Arlt’s, 458, 458f

Lubricant

 

Lax eyelid syndrome, 406-408, 407f

fingerprint, 486

in episcleritis, 578

 

Legal issue, 63-81

Vogt’s, 490

in exposure keratopathy, 508

 

documentation as, 78-79, 78b

Lineate incision of eyelid, 410-412, 411f

Lucentis, 35t, 306-307

 

drug use complications as, 75-78

Lipid layer of tear film, 263, 264f, 416

Lumigan, 687-688, 687t

 

diagnostic, 75-76

evaluation of, 421

Lumiracoxib, 751t

 

therapeutic, 76-78

Lipid monolayer of years, 17

Lutein for age-related macular

 

informed consent as, 65-70

Lipitor, 749t

degeneration, 636

 

alternatives to drug therapy and, 69

Lissamine green, 290-291, 291f, 422

Lyme disease

 

disclosure in, 65-70, 66b, 68f, 69f

in exposure keratopathy, 508f

conjunctivitis and, 459

 

documentation in, 70

Lithium

interstitial keratitis in, 516t

 

misdiagnosis as, 73-75, 73t

adverse effects of, 757t

Lymphatic system, in conjunctival

 

practice laws as, 63-70

eye movement caused by, 719

inflammation, 440

 

certification as, 63-64

Liver

M

 

comanagement as, 64-65, 64b

local anesthetic precautions and, 93

 

registration as, 64

penicillin effects on, 182

Macrolide

 

standards of care as, 72-73

Livostin, 254t, 551t

azithromycin as, 192

 

Lens

in seasonal conjunctivitis, 560

clarithromycin as, 191-192

 

adverse drug effects on, 7t, 704-711,

Local anesthetic, 85-95, 323-324. See also

erythromycin as, 191

 

704t

Anesthesia

side effects of, 192

 

in anterior uveitis, 591

classification of, 86b

Macugen, 35t, 305-306

 

contact. See Contact lens

contraindications to, 92-94, 94f

Macular disease, 632-639

 

intraocular, postoperative dislocation

pharmacologic properties of

age-related degeneration

 

of, 612-613, 613f

mechanism of, 85-86

anecortave for, 310

 

spectacle, 42, 42f

physiochemical characteristics of, 85

diagnosis of, 635-636

 

structure of, 23

structure features as, 85

dietary supplements for, 296, 298t,

Leprosy, interstitial keratitis in, 516t

self-administration of, 93-94

299-300, 636-637

 

Leukopenia, 193-194

side effects of, 90-92

etiology of, 635, 635f, 636f

 

Leukotriene, 233

hypersensitivity as, 91-92, 92f

intravitreal drug administration

Levitra, 730

prevention of, 92

for, 51

 

adverse effects of, 749t

psychomotor, 92

management of, 636-639

 

780

Index

 

 

Macular disease—cont’d

Meibomian gland

Mild pain

pegaptanib for, 306

anatomy and physiology of, 415-416

in child, 109

photodynamic therapy in, 304

evaluation of, 423, 423f

in elderly, 110

ranibizumab for, 307

tear film and, 263

Milia, 401, 401f

retinal disease and, 635-639, 635f,

Meibomianitis, 386-388, 387f

Mineral supplement, 295-301. See also

 

636f

in atopic keratoconjunctivitis, 567

Vitamin and mineral

rostaporfin for, 305

dry eye and, 425

supplementation

triamcinolone acetonide for, 308

tetracyclines for, 190

Mini-Tip culturette, 441

vascular endothelial growth factor

Meige’s syndrome, 377

Minocycline

 

and, 305

Mellaril, 756t

adverse effects of, 754t

zinc and, 208

Membrane

on optic nerve, 739-740

cystoid edema, 363f, 632-635, 633f

in adenoviral conjunctivitis, 452

for meibomian gland infection, 387

after cataract surgery, 613-614, 614f

anterior basement, 486-488, 487f

vestibular toxicity of, 190-191

ketorolac for, 236

in bacterial conjunctivitis, 446

Miosis

latanoprost and, 142-143

conjunctival, 439

phenylephrine and, 116

nonsteroidal anti-inflammatory

Descemet’s, 483

reversal of, 120-121, 120f, 121f

 

drugs and, 234-235

Membrane squamous metaplasia, 271

Miotic

dystrophy in, 484t

Mepivacaine, injectable, 87t

for accommodative esotropia, 665

Macular Photocoagulation Study, 291, 637

Mercurial

adverse effects of, 719

Madarosis, 383f

in artificial tears, 270

after pupil dilation, 339

Magnetic resonance imaging in thyroid

effects of, 30

complications of, 77

 

disease, 650-651, 651f

Meretoja syndrome, 485t

pilocarpine and, 168-170, 168t, 171b

Malignant tumor of eyelid, 402t

Metabolic acidosis, 162

side effects of, 169b

basal cell carcinoma as, 403-404, 403f,

Metabolic disease, scleritis

Misdiagnosis

 

404f

with, 577b

negligence and, 70

signs of, 402b

Metallic corneal foreign body, 498f

of open-angle glaucoma, 73-74

squamous cell carcinoma as, 404-405,

Metalloproteinase inhibitor, 190

of retinal detachment, 74-75

 

405f

Metaplasia, membrane squamous, 271

therapeutic drug use related to, 77-78

Malnutrition, conjunctiva and, 478

Methazolamide, 163-164

of tumor, 74

Mannitol in glaucoma, 694

adverse effects of, 755t

Mite. See Demodex entries

Mannitol salt agar, 441

pharmacokinetic properties of, 161t

Mitomycin

Map, anterior basement membrane

Methicillin, 180t

for pterygia, 478

 

dystrophy and, 486

Methicillin-resistant penicillin, 181

reduced tear production and, 715

Marfan’s syndrome, 335

Methicillin-resistant Staphylococcus

in vernal keratoconjunctivitis, 566

Marijuana, lacrimation and, 715

aureus, 185, 449

Mnemonic

MARINA trial, 307, 308, 638

Methicillin-resistant Staphylococcus

CARVES, 677

Massage in congenital epiphora, 430, 430f

epidermidis, 185

NOSPECS, 645-646, 646t

Mast cell, 549

Methimazole, 652-653

Moclobemide, 690t

Mast cell activation, 246f

Methotrexate

Model of surface inflammation, 240

Mast cell stabilizer, 255, 256t, 257, 550,

adverse effects of, 754t

Moderate pain

 

552t, 553t, 558t-559t

for polyarteritis nodosa, 472

in child, 109

contact lens-related papillary

for psoriasis, 465

in elderly, 110

 

conjunctivitis and, 564

8-Methoxypsoralen

Moisture Eyes, 267t

in seasonal conjunctivitis, 560-561

adverse effect of, on lens, 704t

Moisture Eyes PM, 272t

in vernal keratoconjunctivitis, 566

adverse effects of, 757t

Moisture Liquigel, 267t

Mast cell-antihistamine combination,

adverse effects of, on cornea, 711

Moll cyst of eyelid, 401, 401f

 

257, 258t, 259

Methylene blue, 292

Molluscum contagiosum

Maxipime, 184t

Methylphenidate, 718

conjunctivitis and, 458-459, 458f

Maxitrol, 464

Methylprednisolone, 657

of eyelid, 396-397, 396f

Mebendazole, 630

Metipranolol, 152

Monitoring, 3-4

Medennium SmartPLUG polymer, 273t

formulations of, 146t

Monoamine oxidase inhibitor

Medial canthus technique, 346

for glaucoma, 689t

contraindications to, 690, 690t

Medical history, importance of, 4t, 5

MetroGel, 464

phenylephrine and, 117

Medicamentosa, 513

Metronidazole, 464

Monoclonal antibody for retinal disease,

Medication history, importance of, 4t, 5-6

Mezlocillin, 180t

306-308

Medrysone

Micafungin, 208, 210t, 212t, 213t,

Monocular trial glaucoma, 686-687

clinical uses of, 228

214-215

Moraxella

formulations of, 227t

Miconazole, 208, 211t, 213, 213t

azithromycin for, 192

ocular hypertension and, 231

Microbial keratitis, 540t

conjunctivitis and, 459

MEDWatch form, 742f-743f

Microcyst, epithelial, 542-545, 544f

corneal ulcer and, 521t

Meesmann’s dystrophy, 484t

Microflora, 184

Morpheaform basal cell carcinoma, 403

Mefoxin, 184t

Microvillus, 263, 264

Morphine, 104

 

 

Index

781

Mortality, atropine causing, 129

Mydriacyl Ophthalmic, 127t

Natamycin, 208, 209t, 211t, 213t

 

Motion sickness, 130

Mydriasis

for Acanthamoeba, 216t

 

Motrin, 102t

atropine causing, 129

in fungal keratitis, 536

 

adverse effects of, 751t

corticosteroid causing, 232

National Registry of Drug-Induced

 

Mouth, dry

drugs causing, 22

Ocular Side Effects, 116

 

apraclonidine causing, 155

jimson weed, 361-362

N-chlorotaurine, 526

 

brimonidine and, 157

unilateral fixed and dilated pupil in,

Nd:YAG laser

 

Movement, eye, drugs causing, 719-720,

361-362, 361f, 362, 362f

for posterior capsular opacity, 612

719t

Mydriatic agent, 114-119

stromal puncture with, 506

 

Moxifloxacin, 194t, 195

adrenergic innervation and, 113-114

Necrolysis, toxic epidermal, 469-470

in burn injury, 510

adverse effects of, 718-719, 718b

Necrosis, progressive outer, 624-626,

for conjunctivitis, 449

in angle-closure glaucoma, 693

625f, 625t

 

for corneal ulcers, 523-524

angle-closure glaucoma induced by,

Necrotizing herpetic retinopathy, 620-626

for foreign body, 500

335-336

acute retinal necrosis as, 620-621, 620f

pathogens susceptible to, 442t

cocaine as, 119

cytomegalovirus causing, 621-624,

in recurrent corneal erosion, 505

complications of, 75-76

621f, 622f, 622t

 

in thyroid-related orbitopathy, 656

guidelines for, 333-334

progressive outer retinal necrosis as,

for toxic keratitis, 514

hydroxyamphetamine as, 117-119,

624-626, 625f, 625t

 

Mucin layer of tear film, 264, 416-417

118f

Necrotizing interstitial keratitis, 528-529

Mucoadhesive performance of

phenylephrine as, 114-117

Necrotizing scleritis, 580

 

polymer, 32t

clinical uses of, 114-116

immunosuppression in, 585

 

Mucocyst, 555t

contraindications to, 117

without inflammation, 579

 

Mucoid cyst of eyelid, 401, 401f

pharmacology of, 114

Nedocromil, 255, 256t, 257, 553t

 

Mucolytic agent, 429

side effects of, 116-117

Needle for foreign body removal, 499,

in artificial tears, 271

spray as, 43, 43f

499f

 

Mucous fishing syndrome, 426, 426f, 480

for uveitis, 594

Negligence, 70-72

 

Mucous membrane disorder of

Mydriolytic agent, 119-121, 120f, 121f

proof of, 71-72

 

conjunctiva, 467-470

adrenergic innervation and, 113-114

Neisseria gonorrhoeae

 

cicatricial pemphigoid and, 467-469,

Myobloc, 379

cephalosporin for, 183

 

467f, 468f

Myokymia, 407-408

conjunctival culture for, 441

 

in erythema multiforme major, 469-470

Myopia

conjunctivitis and, 447, 448

 

in Stevens-Johnson syndrome, 469-470

acetazolamide causing, 162

hyperacute, 449-451, 450f

 

in toxic epidermal necrolysis, 469-470

atropine for, 128

infections caused by, 177, 178t

 

Mucous plaque keratitis, 532f, 533

cycloplegic refraction in, 343

penicillin for, 181

 

Mucus fishing syndrome, 480

drugs causing, 720-722, 720b, 721f

Neisseria meningitidis, 450

 

Müller’s muscle, 353

sulfonamides and, 194

Nelfinavir, 207t

 

Multi-drug therapy, 703

N

Nematode endophthalmitis, 629-630

Mumps, 516t

Neodymium:yttrium aluminum garnet

Munchausen syndrome

N-3 fatty acid, 276

laser

 

conjunctivitis in, 480

NaEDTA chelation, 495

for posterior capsular opacity, 612

ocular, 480

Nafcillin, 180t

stromal puncture with, 506

 

Muscarinic receptor, 125-126

Na+-K+-adenosine triphosphatase,

Neomycin, 187-188

 

Muscle

carbonic anhydrase inhibitor

for conjunctivitis, 447-448

 

extraocular

and, 159

of Acanthamoeba, 216t

 

adverse drug effects on, 719-720,

Naphazoline, 247, 248t, 249, 254t

formulations of, 187t

 

719t

in episcleritis, 578

for pathogens susceptible to, 442t

in thyroid disease, 645, 656

Naphcon, 248t

steroids with, 188t

 

in myasthenia gravis, 373, 374

Naphcon-A, 254t, 551t

Neomycin-polymyxin B-dexamethasone,

Myambutol, adverse effects of, 753t

Naprosyn, 102t

464

 

Myasthenia gravis, 372-376

adverse effects of, 751t

Neonate

 

clinical features of, 373-374, 373f

for uveitis, 595

gonococcal ophthalmia in,

 

diagnosis of, 373

Naproxen

tetracyclines for, 190

 

epidemiology of, 373

adverse effects of, 751t

phenylephrine and, 117

 

etiology of, 372-373

for child, 109t

pupil dilation in, 334-335

 

management of, 375-376

formulation of, 102t

Neoral, 595

 

pharmacologic evaluation of, 374

for uveitis, 595

Neostigmine, 374

 

testing for, 374-375, 375f

Narrow angle

Neovascular glaucoma, 693

 

Mycamine, 210t

after iridectomy, 336-337, 337f

Neovascularization

 

Mycophenolate

pupil dilation in, 335-336

in atopic keratoconjunctivitis, 466, 466f

in myasthenia gravis, 376

Nasal field defect, 682f-683f

contact lens-related, 541f

 

for uveitis, 595

Nasolacrimal duct, 417-418

in retinal disease, 619-620

 

Mycoplasma pneumoniae, 192

in congenital epiphora, 429-430

in uveitis, 588

 

782 Index

Nepafenac

clinical uses of, 236 in episcleritis, 578

Nephrolithiasis, 165 Nephropathy, diabetic, 163 Neptazane, 755t

Nerve

nociceptors and, 97 sensory, of eyelid, 324f

Nerve block, regional, 323-324, 324f Nerve fiber

in Horner’s syndrome, 352 myelinated, 113

retinal, in glaucoma, 676-678, 678f unmyelinated, 113

Nerve palsy sixth, 666-669

third, 360-361, 361f Neuralgia, postherpetic, 395-396 Neuron, preganglionic, 113

Neuro-ophthalmic disorder, 349-379 Adie’s syndrome as, 357-360, 358b,

358f, 359f, 359t

anisocoria as, 349-352, 350b, 351f, 351t, 352t

benign essential blepharospasm as, 376-379, 376f, 378t

hemifacial spasm as, 376-379, 378f Horner’s syndrome as, 352-357

diagnosis of, 353-357, 354b, 354f, 355t, 356f, 357t

etiology of, 353b management of, 357 overview of, 352-353

myasthenia gravis as, 372-376, 373f, 375f

of optic nerve, 362-372. See also Optic nerve disease

unilateral fixed and dilated pupil as, 360-362

in adrenergic mydriasis, 362

in anticholinergic mydriasis, 361362, 362f

damage to iris causing, 362

in third nerve palsy, 360-361, 361f Neuropathy, toxic optic, 300 Neurotoxicity of aminoglycosides, 189 Nevanac, 236t

Nevirapine, 206t

Newborn, dacryocystitis in, 182. See also Infant

Niacin, 741, 759t

Nialamide, 690t

Nimesulide, 751t Nit, 398-399

Nocturnal lagophthalmos, 508 Nodular basal cell carcinoma, 403

Nodular episcleritis, 575, 576, 576f, 577t, 578-579

Nodular scleritis, 580-581, 581f Nolvadex, 753t Non-Acanthamoeba keratitis, 217

Noncholinergic agent, 119-121, 120f, 121f

Noncompliance, 59-60, 60b

with glaucoma treatment, 695-696 Nonimmune defense barrier of

conjunctiva, 444 Noninfiltrative thyroid-related

orbitopathy, 644, 646-647, 647f management of, 652

Nonnarcotic analgesic combination, 103-104

nonsteroidal anti-inflammatory drugs as, 100-102, 100b, 101t

salicylates as, 98-100, 99t Nonnucleoside reverse transcriptase

inhibitor, 206t Non-Sjögren’s syndrome, 425-426

Nonspecific viral conjunctivitis, 459 Nonsteroidal anti-inflammatory drug,

233-236

adenoviral conjunctivitis and, 454 adverse effects of, 751t

retinal, 731

for allergic disease, 259, 550, 554t, 558t-559t

clinical uses of, 101-102 contact lens-related papillary

conjunctivitis and, 564 contraindications to, 102 for corneal abrasion, 496 cystoid macular and, 633 for elderly, 110

in episcleritis, 578-579

for exposure keratopathy, 509 for foreign body, 500 mechanism of action of, 97-98

in pain management, 108-109, 109f pharmacology of, 100-101, 233-235,

234f

for postoperative inflammation, 602 for pseudophakic cystoid macular

edema, 614

in Reiter’s syndrome, 473 in scleritis, 584

for seasonal conjunctivitis, 561 side effects of, 102

for tear augmentation, 429 for uveitis, 595

Nontuberculous phlyctenular keratoconjunctivitis, 190

Norfloxacin, 194t, 195 formulations of, 186t

Norvir, 207t

NOSPECS classification, 645-646, 646t Nucleic acid amplification test, 444 Nucleoside reverse transcriptase

inhibitor, 206t

Nucleus, Edinger-Westphal, 125 Nuprin, 102t

Nursing patient. See Breast feeding NutraTear, 267t

Nutrient of artificial tears, 270-271

Nutritional agent, 295-301, 703. See also Vitamin and mineral supplementation; Vitamin entries

Nystagmus test, alcohol gaze, 720

O

Occlusion

for amblyopia, 664

of lacrimal puncta, 426-427, 432-433 retinal vein, 632, 634

vascular, 580

Occlusive device, lacrimal, 273-274, 273f, 274f

OctreoScan, 651

Octreotide, 659 Ocufen, 235, 236t

Ocular adnexa in allergy, 550

Ocular adverse drug reaction, 701-759. See also Adverse drug reaction

Ocular cicatricial pemphigoid, 467-469, 467f, 468f

Ocular coherence tomography anterior segment, 675

in retinal disease, 307 Ocular effect

of beta-blocker, 148b of systemic drug, 9 of topical drug, 7-8

Ocular history, importance of, 4-5, 4t Ocular hypertension. See also

Glaucoma; Hypotensive drug; Intraocular pressure

as cataract surgery complication, 608 corticosteroid induced, 229-232, 241f

Ocular Hypertension Treatment Study, 680, 682, 696t

Ocular hypotony, 607, 607f Ocular immunology, 549-550

Ocular Munchausen syndrome, 480 Ocular pain, analgesics for, 97-111. See

also Analgesic

Ocular response analyzer, 674 Ocular surface

anatomy and physiology of, 415 disorders of, 263-278, 424-425. See

also Dry eye evaluation of, 422-423, 423f

Oculosympathetic paresis, 353, 354-355 Oculosympathetic pathway, 113-114, 114f

in Horner’s syndrome, 352 Ocupress, 146t

Office test for myasthenia gravis, 374 Off-label use of bevacizumab, 308 Ofloxacin, 194t, 195

for conjunctivitis, 448-449 for corneal ulcer, 523, 524 formulations of, 186t

for infectious conjunctivitis, 446 for pathogens susceptible to, 442t

Ointment

administration of, 43-44, 44f complications of, 44-45

Ointment—cont’d

sodium chloride, in Fuchs’ dystrophy, 489

for tear conservation, 272-273, 272t tretinoin, 271

as vehicle, 34

Olopatadine, 254, 257, 258t, 259, 552t, 553t

in seasonal conjunctivitis, 561 Omega-3 fatty acid

dry eye and, 300

inflammatory response and, 233 for tear augmentation, 428-429

Omnicef, 184t Onchocerciasis, 516t

Opacification, posterior capsular, postoperative, 611-612, 612f

Opcon-A, 254t Open-angle glaucoma

acetazolamide and, 163 betaxolol for, 151 carteolol for, 152-153

corticosteroids and, 723-724 dorzolamide and, 165 misdiagnosis of, 74-75

nutritional supplements for, 297-298 pupil dilation in, 335

travoprost and, 143 Ophthalmia

gonococcal, 190

sympathetic, Cyclosporine A for, 241 Ophthalmia neonatorum, 460-463

causes of, 463t chemical, 462

Chlamydia trachomatis, 461, 461f, 462f herpes simplex virus, 462

Neisseria gonorrhoeae, 460-461, 461f other bacterial causes of, 462 prevention of, 462-463

Ophthalmoscopy

confocal scanning laser, 679, 679t in glaucoma, 676

Opioid, 104-108

clinical uses of, 106-107 commonly used, 105t contraindications to, 107-108 cross-sensitivity among, 108t pharmacology of, 104-106 pupillary effects of, 719

side effects of, 107, 107b Optic nerve

drugs adversely affecting, 736-741, 736t

amiodarone, 738 chloramphenicol, 737-738 ethambutol, 736-737, 736t sildenafil, 738-739 tetracyclines, 739-740

in glaucoma, 676-678, 678f hemorrhage of, 678-679

in sarcoidosis, 632 structure of, 24

Optic neuropathy, 362-372 anterior ischemic, 368-369 demyelinating, 369-370 infectious, 367-368 infiltrative, 366-367 Leber’s hereditary, 372 nutritional, 370-372 overview of, 362-364

papilledema causing, 364-366, 364t, 365f

pseudotumor cerebri and, 365f, 366 in thyroid disease, 650, 657

toxic, 300, 370-372, 371b Optical coherence tomography

in glaucoma, 679, 679t in uveitis, 599

Opticrom, 561 Opticrom Crolom, 256t OptiPranolol, 146t Optivar, 258t, 553t

in seasonal conjunctivitis, 561 Optometrist, certification of, 63-64 Oral contraceptive

adverse effects of

reduced tear production, 714-715 retinal, 730-731

penicillin effects on, 182

Oral fluorescein angioscopy, 288 Oral hypoglycemic drug, 194 Orbicularis muscle, 374

Orbital cellulitis, 391t. 392 penicillin for, 181

Orbital decompression, 657, 660-661, 660f

Orbital radiotherapy, 655, 660 Orbitopathy, thyroid-related, 643-662. See

also Thyroid-related orbitopathy Osmolarity, bioavailability and, 28 Ototoxicity

of erythromycin, 192 of vancomycin, 185-186

Outer retinal necrosis, progressive, 624-626, 625f, 625t

Overdose

of atropine, 129 cholinergic, 666

Over-the-counter drug, 5 Oxacillin, 180t Oxaprozin

adverse effects of, 751t formulation of, 102t

Oxychloro-complex in artificial tears, 270

Oxycodone formulations of, 105t

pharmacological properties of, 104t Oxygen in photodynamic therapy, 303 Oxymetazoline, 249

in episcleritis, 578 Oxytetracycline

formulations of, 187t polymyxin B with, 190

Index 783

P

Pachymetry, 321, 322f

Packaging of solutions and suspensions, 39, 40f

Pain

analgesics for, 97-111. See also Analgesic

in bullous keratopathy, 494

in herpes zoster ophthalmicus, 395, 533

management of, 108-109, 109f mechanism of, 97-98 postoperative, 603

Palpebral conjunctiva, 437, 438f, 480 Palpebral fissure

in burn injury, 509

in thyroid-related orbitopathy, 654, 654f Palpebral vernal keratoconjunctivitis, 565 Palsy

sixth nerve, 666-669 third nerve, 360-361, 361f

Pamidronate, 752t Panatol, 552t Panuveitis

description of, 587 diagnosis of, 593

Papillary conjunctivitis, giant, 558t contact lens-related, 542f loteprednol etabonate for, 228 mast cell stabilizers for, 255

Papillary hypertrophy, 439, 440t Papilledema, 364-366, 364t, 365f Papilloma

anesthesia for, 326-327, 327f of eyelid, 399-402, 400f, 401f

Parahydroxybenzoic acid ester, 270 Paralytic agent, 666-669, 667b

adverse effects of, 668-669 clinical uses of, 666-668 pharmacology of, 668

Parasitic infection, 626-630 scleritis with, 577b toxocariasis as, 629-630, 629f

toxoplasmosis as, 626-630, 636f, 637f Parasympathetic nervous system, 113 Parasympathomimetic, 688-689, 688t Paremyd

hydroxyamphetamine and, 118 tropicamide and, 135-136

Parinaud’s oculoglandular syndrome, 459-560, 460b

Pars planitis, 632 Pataday, 258t, 553t

in seasonal conjunctivitis, 561 Patanol, 258t

in seasonal conjunctivitis, 561 Patching for amblyopia, 664 Pathogen, common conjunctival, 438 Patient counseling, 60-61

Patient education

on cataract surgery, 601 importance of, 3-4

784

Index

 

 

Patient history, importance of, 4-6, 4t

Pharmacokinetics—cont’d

Phlyctenule

PDE-5, 730

drug development and, 36

conjunctival, 517

PDE-6, 730

drug properties affecting, 27-36

corneal, 517-518

Peaked pupil, 609-610, 610f

active ingredients as, 28, 29t

Phlyctenulosis, 474-475, 475f

Pediatric patient. See Child

bioavailability as, 27-28, 27f

PHMB, 215, 216t

Pediculocidal agent, 399

osmolarity as, 28

Photochemotherapy, 466

Pediculus humanus, 397-399

preservatives as, 28, 30-31

Photodynamic therapy, 51

Pegaptanib, 305-306

stability as, 28

for age-related macular degeneration,

for age-related macular degeneration,

vehicles as, 31-34, 31b, 32t, 33f

637

 

638

drug release systems as, 34, 35t, 36

for retinal disease, 303-305

Pemirolast, 255, 256t, 257, 553t

of iris, 22

Photography in anisocoria, 350

Pemphigoid, cicatricial, 467-469, 467f,

of ocular structures, 17-37

Photokeratitis, 511-512

 

468f

prodrugs and, 27

Photo-oxidative stress, 635

Penalization, atropine, 664-665, 665b

of retina and optic nerve, 24-25, 24t

Photopic condition, 157

Penetrating corneal injury, 502-504-502f,

of sclera and cornea, 19-22, 20f, 21f, 21t

Photorefractive keratectomy, 236

 

503f, 504f

of tear film, 17-19, 18f, 19f

Photorefractive surgery, dry eye after, 265

Penetrating keratoplasty

of vitreous humor, 23-24

Photosensitivity

for Acanthamoeba keratitis, 538

Pharmacologic blockade, 361

pupil dilation and, 339

in Fuchs’ dystrophy, 489f

Pharmacotherapy, 3-15

tetracyclines causing, 190

in fungal keratitis, 536

adverse reactions to

verteporfin and, 304

in recurrent corneal erosion, 506-507

ocular, 7-8, 7t, 8f

Photosensitizing drug, 711

in trauma, 503-504

systemic, 8-9, 9t

Phototoxicity of fluoroquinolones, 195

Penetration, drug, scleral, 20

in child, 11-12, 11t

Photrex, 305

Penicillin, 179-183

determining contraindications to

Phthiriasis palpebrarum, 397-399, 398f

antipseudomonal, 180t, 182

clinical examination in, 6-7

Physician, comanagement with, 64-65, 64b

clinical uses of, 181-182

patient history in, 4-6, 4t

Physiologic anisocoria, 352

contraindications to, 182-183

in difficulty swallowing, 14

Physostigmine

extended spectra of activity in, 180t,

in elderly patient, 12-13

for atropine overdose, 129

 

181-182

incidence of, 5

for phthiriasis palpebrarum, 399

for gram-positive bacteria, 180t, 181

initiating, 3-4

Pigmentary glaucoma, 335

for internal hordeolum, 390

monitoring, 3-4

Pigmentation

pharmacology of, 179

in pregnancy, 9-11, 10f

in anterior uveitis, 591

in preseptal cellulitis, 391

in visually handicapped patient, 13-

chlorpromazine causing, 712

resistant to penicillinase, 180t, 181

14, 13f-14f

of iris, 22

side effects of, 182

Pharyngoconjunctival fever, 452, 453t

in Horner’s syndrome, 354

Penicillinase, 181

epidemic keratoconjunctivitis versus,

latanoprost and, 141-142

Penicillin-resistant Streptococcus

527

phenylephrine and, 116

 

pneumoniae, 185

Phenelzine, 690t

tetracycline causing, 713, 718

Penicillum, 534

Phenergan, 251t

Pilocarpine

Pentamidine, 215

Pheniramine, 254t, 551t

in Adie’s syndrome, 359, 359f, 359t, 360

Pentazocine, 104t

side effects of, 255

in angle-closure glaucoma, 693

Pentolair, 127t

Pheniramine-naphazoline, 254

in anisocoria evaluation, 352t

Peptostreptococcus, 391

Phenol red thread test, 421

in anticholinergic mydriasis, 362, 362f

Perennial conjunctivitis, 550, 560-561 560f

Phenothiazine

clinical uses of, 168

Perforation, globe, 581

accommodation disturbance

contraindications to, 170, 170b

Peribulbar anesthesia, 604

and, 721

for glaucoma, 688-689, 688t

Peribulbar injection, 49-50, 49f

adverse effects of, 756t

lacrimation and, 715

Perimetric test of visual function, 680t

Phenylephrine, 114-117, 247, 248t, 249

pharmacology of, 168

Periocular steroid

in angle-closure glaucoma, 693

side effects of, 168-169, 169b

for uveitis, 594, 596-597

clinical uses of, 114-116

systemic effects of, 9t

Periorbital cellulitis, 391-393, 391t, 392f

contraindications to, 117

for tear stimulation, 274

Periorbital dermatosis, 568

for corneal abrasion, 497

in third nerve palsy, 360-361, 361f

Peripapillary atrophy, 678, 678f

dapiprazole and, 120

Pilopine HS, 688t

Peripheral ulcer, 540t

in episcleritis, 578

Pimaricin, 208

Petrolatum ointment, 399

hydroxyamphetamine and, 118

Pimecrolimus, 555t

pH of tears, 17

for infant or child, 334

for atopic dermatitis of eyelid, 570

Pharmacokinetics

pharmacology of, 114

Pioglitazone, 660

of aqueous body, 23

side effects of, 116-117

Piperacillin

blood supply and, 25

in systemic disease, 335

for pseudomonal infection, 182

of ciliary body, 23

Phlyctenular keratoconjunctivitis,

spectrum of activity of, 180t

compartment theory and, 25-27, 26f

517-518, 518f

Pityrosporum ovale, 385

of crystalline lens, 23

tetracyclines for, 190

Plaquenil, 749t

Plasma protein acetazolamide and, 160 aspirin and, 100

Plasmapheresis

in myasthenia gravis, 376

in thyroid-related orbitopathy, 658 Plasminogen activator, 309

Plateau iris, 338 Platelet, 98, 103 Pledget, cotton, 47, 47f Plug

collagen, 273-274, 273f, 273t, 427 punctal, 426-427

anesthesia for, 323

Polarimetry, scanning layer, 679, 679t Polyacrylic acid, 33-34

Polyarteritis nodosa, 471-472, 472f Polyene, 205

Polyene antifungal drug, 208, 209t-210t Polyhexamethylene biguanide, 215 Polyionic vehicle, 33

Polymer, 32t

Polymerase chain reaction, 444 Polymer-based artificial tears, 266.

See also Artificial tears Polymyxin B, 186-187, 187t

for conjunctivitis, 447, 448 formulations of, 187t

for pathogens susceptible to, 442t in phlyctenulosis, 475

steroids with, 188t Polymyxin B-bacitracin, 513

Polysaccharide artificial tears, 266-268 Polyvinyl alcohol, 32, 268-269 Polyvinylpyrrolidone, 32 Posaconazole, 208

Posner-Schlossman syndrome, 694 Posterior capsular opacification, 611-612,

612f

Posterior limiting membrane, 483 Posterior polymorphous dystrophy, 485t Posterior scleritis, 582-584, 583f Posterior segment

in sarcoidosis, 632

in toxoplasmosis, 627 Posterior subcapsular cataract

steroid-induced, 705 uveitis and, 596

Posterior uveitis complications of, 597 description of, 587 diagnosis of, 592-593

Postganglionic neuron, 352-353 Postherpetic neuralgia, 395-396 Postoperative inflammation, 228 Posurdex, 35t

Posurdex implant, 309 Povidone iodine, 454 Practice law

certification as, 63-64 comanagement as, 64-65, 64b registration as, 64

Precipitate, keratic, in uveitis, 587 Pred Forte, for cataract patient, 64b Prednisolone

for allergic disease, 554t

in angle-closure glaucoma, 693 in burn injury, 510-511 cataract cause by, 705

for corneal ulcers, 525 cystoid macular and, 633 dosages schedule for, 227t formulations of, 227t

for herpes simplex keratitis, 529

for phlyctenular keratoconjunctivitis, 518

in Reiter’s syndrome, 473 in scleritis, 584-585

for Stevens-Johnson syndrome, 469 for Thygeson’s superficial punctate

keratitis, 534 in toxocariasis, 630

in vernal keratoconjunctivitis, 566 Prednisone

adverse effects of, 750t in myasthenia gravis, 375

for ocular cicatricial pemphigoid, 468 in sarcoidosis, 632

in thyroid disease, 656, 657 for toxoplasmosis, 628

Preganglionic neuron, 113 in Horner’s syndrome, 353

Pregnancy

acetaminophen and, 103 antihistamines in, 253-254 aspirin and, 100 clarithromycin and, 192 cocaine and, 119 contraindications related to, 5 NSAIDs and, 103

opioid and, 107 precautions in, 9-11, 10f pupil dilation and, 335

sulfonamides contraindicated in, 194 toxoplasmosis and, 628

Pre-instillation anesthesia, 322 Premature infant, 334 Prescribing spectacles, 347-348 Prescription, 54-58

anatomy of, 54-56, 54f, 55t, 56b

for controlled substances, 57, 57t, 58f effective, 56-57

preventing forgery of, 58 types of, 56

Preseptal cellulitis, 391-393, 391t, 392f antibacterial drugs for, 176t penicillin for, 182

Preservation, tear. See Tear conservation Preservative

in artificial tears, 270 bioavailability and, 28, 30-31 damage caused by, 8

Pressure, intraocular. See Intraocular pressure

Index 785

Presurgical evaluation, 324-325 Pretarsal subcutaneous block, 324 Prevention

of adverse drug reactions, 741, 746 of ophthalmia neonatorum and,

462-463

of toxocariasis, 630 Prexige, 751t Prezista, 206t

Probe, lacrimal, 430, 431f Probenecid, 181 Procaine, 87t

Prodrug, 27 Product liability, 78 Profenal, 236t

Professional community standard, 66, 66b

Prograf, 595

Progressive outer retinal necrosis, 624-626, 625f, 625t

Promethazine, 250, 251t Propamidine, 216t Proparacaine, 89-90

abuse of, 513-514 for culture, 320

for foreign body removal, 322-323 for lacrimal drainage procedure, 322 for punctal plug insertion, 323

for superficial abrasion, 320 Proparacaine-sodium fluorescein, 320 Prophylactic antibiotic

in bullous keratopathy, 494 for cataract surgery, 601 for contact lens-related

complications, 540 for corneal abrasion, 497 dellen and, 512-513

for phlyctenular keratoconjunctivitis, 518

in recurrent corneal erosion, 505

Propionibacterium acnes, 382-383 in conjunctival flora, 438 endophthalmos and, 606

Propoxyphene formulations of, 105t

pharmacological properties of, 104t, 105-106

Propranolol, 377

Proptosis in thyroid-related orbitopathy, 643-644

characteristics of, 648, 649t management of, 652, 654, 656

Propylthiouracil, 652-653 Prostaglandin

in glaucoma, 687-688, 687t inflammatory response and, 233 nonsteroidal anti-inflammatory drugs

and, 235 Prostaglandin analogue

brimonidine and, 156

as hypotensive drug, 139-145 bimatoprost, 144-145, 145f

786

Index

 

 

Prostaglandin analogue—cont’d

Ptosis—cont’d

Ranibizumab, 306-307

latanoprost, 139-143, 140b, 140f,

in myasthenia gravis, 373, 373f

for age-related macular degeneration,

 

141b, 142f, 145f

Pulmonary function, betaxolol and, 151

638, 639

travoprost, 143-144, 145f

Punctal dilation, 432f

Rapidly progressive herpetic retinal

nonsteroidal anti-inflammatory drugs

Punctal disorder, 432-433

necrosis, 624-626, 625f, 625t

 

and, 235

Punctal plug, 428f

Rash

Prostaglandin compound, 145

anesthesia for, 323

penicillin causing, 182

Protease inhibitor, 206t-207t

Punctate bacterial keratitis, superficial,

sulfonamides causing, 194

Protein

514-515, 514f

RCE. See Recurrent corneal erosion

methazolamide and, 163

Punctate epithelial corneal erosion, 143

Reasonable patient standard, 66, 66b

in uveitis, 588

Punctate keratitis,Thygeson’s

Rebound miosis, 116

Protein kinase C, 311-312

superficial, 241-242

Recall, documentation of, 79

Protein synthesis, antibacterial drug

Punctate keratopathy, 514

Receptor

 

affecting, 187-193

Puncture, anterior stromal, 506

cholinergic, 125

amikacin as, 190

in recurrent corneal erosion, 507

FP, 139

aminoglycosides as, 187-190

Pupil. See also Mydriatic agent

histamine, 245-247, 246f, 246t

chloramphenicol as, 192-193

in anisocoria, 349

muscarinic, 125-126

gentamicin as, 188

in anterior uveitis, 590

Receptor-mediated inflammatory

macrolides as, 191-192

cholinergic innervation and, 125, 126f

process, 264

neomycin as, 187-188

dilation of, 329-341. See also Dilation

Receptor-mediated inflammatory

tetracyclines as, 190-191, 190t

of pupil

response, 264

tobramycin as, 189

complications of, 75-76

Record of patient care, 79

Proteus

disclosure of risks of, 67-69,

Recreational drug, 703

conjunctivitis and, 448, 451

68f, 69f

Recurrent corneal erosion, 486, 487,

infections caused by, 177

mydriatic agent for, 114-119. See

504-507, 504f, 507f

Protoptic, 555t, 570

also Mydriatic agent

Recurrent herpes simplex keratitis, 528

Protozoan infection, 215, 216t, 217

examination of, 6

Red eye, contact lens-related, 540t

Pruritus, 571

postoperative distortion of, 609-610,

Redness in anterior uveitis, 590

Pseudomembrane

610f

Referral, 79

in adenoviral conjunctivitis, 452

unilateral fixed and dilated, 360-362

Refraction

in epidemic keratoconjunctivitis, 525

adrenergic mydriasis causing, 362

atropine and, 128

in inflammation, 439

anticholinergic mydriasis causing,

cycloplegic, 6, 343-348. See also

Pseudomembranous colitis, antibiotic-

361-362, 361f, 362f

Cycloplegic refraction

 

associated, 184

iris injury causing, 362

Refractive error, 345

Pseudomembranous conjunctivitis, 447

third nerve palsy causing, 360-361,

Refractive surgery, 265

Pseudomonas, 448

361f

Refresh, 267t

Pseudomonas aeruginosa

Pupillary block glaucoma, 67

Refresh Endura, 427t

aminoglycosides for, 187

Purified protein derivative, in uveitis, 598

Refresh PM, 272t

cephalosporin for, 183

Purite, 156, 270

Refresh products, 427t

in conjunctival flora, 438

PUVA, for psoriasis, 466

Regional nerve block, 323-324, 324f

corneal ulcer and, 520, 521t, 522f

PVP, 269

Registration, 64

infections caused by, 177, 178t

Pyrethrin, 399

Regulatory issues for prescription

ophthalmia neonatorum and, 462

Pyridostigmine bromide, 375

writing, 54-58, 54f, 55t, 58b

penicillin for, 182

Pyrimethamine, 193-194

Reis-Bücklers dystrophy, 484t

Pseudophakia, 605t. See also Cataract

for toxoplasmosis, 627-628

Reiter’s syndrome, 472-474, 473f

 

surgery

Pyrimidine, 205, 208

Release, drug, 34, 36

Pseudophakic cystoid macular edema,

Q

Relief decongestant, 248t

 

613-614, 614f, 633

Remicade, 595

Pseudotumor cerebri

Quality of care, 53

Renal disorder

drug-induced, 739

Quality of life in glaucoma, 695-696

contraindications related to, 5

optic neuropathy in, 365f, 366

Quaternary ammonium compound,

dorzolamide and, 165

tetracyclines and, 190

270

in polyarteritis nodosa, 471-472

Psoralen, 704t

Quetiapine, 757t

Renal function

Psoralen ultraviolet A irradiation, for

Quinine, 750t

acetazolamide and, 163

 

psoriasis, 466

retinal, 734

carbonic anhydrase inhibitor

Psoriasis vulgaris, 465-466

R

and, 162

Psychomotor reaction to local

cephalosporins and, 184-185

 

anesthetic, 92

Race

NSAIDs and, 103

Pterygium, 477-478, 477f

acetazolamide and, 163

Rescriptor, 206t

Ptosis

 

uveitis and, 589

Residual accommodation

botulinum toxin and, 667

Radioactive iodine uptake test, 644

cycloplegics and, 346, 347

corticosteroid causing, 232

Raeder’s syndrome, 355

tropicamide and, 133-134

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