- •Foreword
- •Preface
- •Acknowledgments
- •Contents
- •List of Contributors
- •List of Abbreviations
- •1. Overview of Botulinum Toxin
- •1.1 Introduction
- •1.3 Mode of Action
- •1.4 Antidote
- •1.5 Different Products
- •1.6 Units of Botulinum Toxin
- •1.7 Off-Label Use
- •1.8 New Drugs
- •1.10 Efficacy: Optimal Dosage
- •1.10.1 Botox
- •1.10.2 Dysport
- •1.11 Effectiveness: Dosages and Repeated Treatments
- •1.11.1 Botox
- •1.11.2 Dysport
- •1.12 Safety
- •1.13 Short-term Safety: Eyelid Ptosis
- •1.13.1 Botox
- •1.13.2 Dysport
- •1.14.1 Botox
- •1.14.2 Dysport
- •1.15 Marketing and Evidence
- •1.16 References
- •2. Patient Selection
- •2.1 Indications for BNT
- •2.1.2 Kinetic Patients
- •2.1.3 Hyperkinetic Patients
- •2.1.4 Hypertonic Patients
- •2.1.5 Outcome Analysis
- •2.1.6 Tips and Tricks
- •2.1.7 References
- •2.2 Contraindications for Botulinum Toxin
- •2.2.1 General Contraindications
- •2.2.1.1 Dysmorphism
- •2.2.2 Drug specific Contraindications
- •2.2.2.1 Diseases with Pathological Neuromuscular Transmission
- •2.2.2.2 Drug Interactions
- •2.2.2.3 Injection related Contraindications
- •2.2.3 References
- •3. Requirements and Rules
- •3.1 Introduction
- •3.2 Documentation
- •3.2.1 Chart
- •3.2.2 Photograph
- •3.2.3 Consent
- •3.2.4 Treatment Plan
- •3.3 Staff
- •3.4 Technical Requirements
- •3.4.1 Room
- •3.4.2 Chair
- •3.4.3 Mirror
- •3.4.4 Cosmetic Marker
- •3.4.5 Standard Setting
- •3.4.6 The Toxin
- •3.4.7 Tips and Tricks
- •3.4.8 References
- •4. Injection Technique
- •4.1 Introduction
- •4.2 Standard Technique
- •4.3 Microinjection Technique
- •4.4 Other Techniques
- •5. The Most Common Indications
- •5.1 Forehead
- •5.1.1 Introduction
- •5.1.2 Anatomy
- •5.1.3 Aim of Treatment
- •5.1.4 Patient Selection
- •5.1.5 Technique
- •5.1.5.1 Standard
- •5.1.5.3 Combination with Glabella
- •5.1.6 Complications
- •5.1.6.1 Brow Ptosis
- •5.1.6.2 Mephisto Sign
- •5.1.7 Tips and Tricks
- •5.2 Glabella
- •5.2.1 Introduction
- •5.2.2 Anatomy
- •5.2.3 Aim of Treatment
- •5.2.4 Patient Selection
- •5.2.5 Technique
- •5.2.6 Complications
- •5.2.6.1 Eyelid Ptosis
- •5.2.6.2 Flattening and Broadening of the Glabella Area
- •5.2.7 Tips and Tricks
- •5.3 Brow lift
- •5.3.1 Introduction
- •5.3.2 Anatomy
- •5.3.3 Aim of Treatment
- •5.3.4 Patient Selection
- •5.3.5 Technique
- •5.3.5.1 Technique 1
- •5.3.5.2 Technique 2
- •5.3.5.3 Technique 3
- •5.3.7 Tips and Tricks
- •5.3.8 References
- •5.4 Crow’s Feet and Lower Eyelid
- •5.4.1 Introduction
- •5.4.2 Anatomy
- •5.4.3 Aim of Treatment
- •5.4.4 Patient Selection
- •5.4.4.1 Crow’s Feet
- •5.4.4.2 Lower Eyelid
- •5.4.4.3 Eye Bags
- •5.4.5 Technique
- •5.4.6 Results
- •5.4.7 Complications
- •5.4.8 Tips and Tricks
- •5.4.9 References
- •5.5 Bunny Lines
- •5.5.1 Introduction
- •5.5.2 Anatomy
- •5.5.3 Aim of the Treatment
- •5.5.4 Patient Selection
- •5.5.5 Technique
- •5.5.7 Tips and Tricks
- •5.5.8 References
- •5.6 Nose
- •5.6.1 Introduction
- •5.6.2 Anatomy
- •5.6.3 Aim of Treatment
- •5.6.4 Patient Selection
- •5.6.5 Technique
- •5.6.5.1 Technique 1
- •5.6.5.2 Technique 2
- •5.6.5.3 Technique 3
- •5.6.6 Results
- •5.6.8 Tips and Tricks
- •5.6.9 References
- •5.7 Nasolabial Fold
- •5.7.1 Introduction
- •5.7.2 Anatomy
- •5.7.3 Aim of Treatment
- •5.7.4 Patient Selection
- •5.7.5 Technique
- •5.7.7 Tips and Tricks
- •5.7.8 References
- •5.8 Cheek Lines
- •5.8.1 Introduction
- •5.8.2 Anatomy
- •5.8.3 Aim of Treatment
- •5.8.4 Patient Selection
- •5.8.5 Technique
- •5.8.7 Tips and Tricks
- •5.8.8 References
- •5.9 Gummy smile
- •5.9.1 Introduction
- •5.9.1.1 Types of Smile
- •5.9.2 Anatomy
- •5.9.3 Aim of Treatment
- •5.9.4 Patient Selection
- •5.9.5 Technique
- •5.9.6.1 Asymmetries
- •5.9.6.2 Upper Lip Drooping
- •5.9.7 Tips and Tricks
- •5.9.8 References
- •5.10 Upper and Lower Lip Wrinkling
- •5.10.1 Introduction
- •5.10.2 Anatomy
- •5.10.3 Aim of Treatment
- •5.10.4 Patient Selection and Evaluation
- •5.10.5 Technique
- •5.10.5.1 Technique 1
- •5.10.5.2 Technique 2
- •5.10.6.1 Functional Impairment
- •5.10.7 Tips and Tricks
- •5.10.8 References
- •5.11 Marionette Lines
- •5.11.1 Introduction
- •5.11.2 Anatomy
- •5.11.3 Aim of Treatment
- •5.11.4 Patient Selection and Evaluation
- •5.11.5 Technique
- •5.11.7 Tips and Tricks
- •5.12 Cobblestone chin
- •5.12.1 Introduction
- •5.12.2 Anatomy
- •5.12.3 Aim of Treatment
- •5.12.4 Patient Selection and Evaluation
- •5.12.5 Technique
- •5.12.7 Tips and Tricks
- •5.13 Platysmal bands
- •5.13.1 Introduction
- •5.13.2 Anatomy
- •5.13.3 Aim of Treatment
- •5.13.4 Patient Selection
- •5.13.5 Technique
- •5.13.7 Tips and Tricks
- •6.1 Facial Asymmetries
- •6.1.1 Introduction
- •6.1.2 Anatomy
- •6.1.3 Aim of Treatment
- •6.1.4 Patient Selection
- •6.1.5 Technique
- •6.1.6 Results
- •6.1.8 Conclusions
- •6.1.9 Tips and Tricks
- •6.1.10 References
- •6.2.1 Introduction
- •6.2.3 Aim of Treatment
- •6.2.4 Patient Selection
- •6.2.5.1 Upper Third Treatment
- •6.2.5.3 Lower Third and Neck
- •6.2.7 Tips and Tricks
- •6.2.8 References
- •6.3 Treatment with Microinjections
- •6.3.1 Introduction
- •6.3.2 Microinjections of the Crow’s Feet Area
- •6.3.4 Doses to be Used
- •6.3.7 Tips and Tricks
- •7.1 Introduction
- •7.2.1 Injection Pain
- •7.2.3 Headache
- •7.2.4 Localized Skin Dryness
- •7.3 Adverse Events Due to Local Diffusion/Distribution
- •7.3.1 Eyelid Ptosis
- •7.3.2 Ectropion
- •7.3.3 Strabismus
- •7.3.4 Pseudoherniation
- •7.3.5 Complications After Perioral and Neck Treatment
- •7.6 Allergies to Botulinum Toxin-A
- •7.7 Formation of Antibodies
- •7.9 References
- •8.1 Introduction
- •8.2 Botulinum Toxin and Chemical Peels
- •8.4 Botulinum Toxin and Fillers
- •8.5 Botulinum Toxin and Brow Lift with Suspension Threads
- •8.7 Botulinum Toxin and Facelift
- •8.9 Tips and Tricks
- •8.10 References
- •Subject Index
List of Contributors
Berthold Rzany MD ScM |
Mauricio de Maio MD, PhD, MSc |
Professor of Dermatology |
Plastic Surgeon |
Clincial Epidemiologist |
Faculty of Medicine of the University of Sao |
|
Paulo |
Hendrik Zielke MD |
Av. Ibirapuera, 2907 - cj. 1202 |
Email: hendrik.zielke@charite.de |
Moema - São Paulo - SP |
Division of Evidence Based Medicine (dEBM) |
CEP: 04029-200 |
Klinik für Dermatologie |
Brazil |
CHARITÉ – UNIVERSITÄTSMEDIZIN |
|
BERLIN |
Phone/fax: 0055 11 55359286 |
CAMPUS CHARITÉ MITTE |
Email: mauriciodemaio@uol.com.br |
Charitéplatz 1 |
|
D - 10117 Berlin |
|
Germany |
|
Phone: 0049 (0)30 - 450518 - 283 |
|
Fax: 0049 (0)30 - 450518 - 927 |
|
Email: berthold.rzany@charite.de |
|
http://www.debm.de or www.rzany-berlin.de |
|
List of Abbreviations
BNT Botulinum toxin
EADV European Academy of Dermatology and Venerology
EBM Evidence Based Medicine
MU Mouse units
