Ординатура / Офтальмология / Английские материалы / Automated Image Detection of Retinal Pathology_Jelinek, Cree_2009

Am J Epidemiol, 150, 263, 1999.

[72]Wang, J.J., Mitchell, P., Leung, H., et al., Hypertensive retinal vessel wall signs in a general older population: the Blue Mountains Eye Study, Hypertension, 42, 534, 2003.

[73]Wong, T.Y., Klein, R., Klein, B.E., et al., Retinal vessel diameters and their associations with age and blood pressure, Invest Ophthalmol Vis Sci, 44, 4644, 2003.

[74]Wong, T.Y., Hubbard, L.D., Klein, R., et al., Retinal microvascular abnormalities and blood pressure in older people: the Cardiovascular Health Study, Br J Ophthalmol, 86, 1007, 2002.

[75]Wong, T.Y., Klein, R., Sharrett, A.R., et al., Retinal arteriolar diameter and risk for hypertension, Ann Intern Med, 140, 248, 2004.

[76]Longstreth, Jr., W.T., Larsen, E.K., Klein, R., et al., Associations between findings on cranial magnetic resonance imaging and retinal photography in the elderly, Am J Epidemiol, 2006.

[77]Wong, T.Y., Barr, E.L., Tapp, R.J., et al., Retinopathy in persons with impaired glucose metabolism: the Australian Diabetes Obesity and Lifestyle (AusDiab) Study, Am J Ophthalmol, 140, 1157, 2005.

[78]Wong, T.Y., Klein, R., Couper, D.J., et al., Retinal microvascular abnormalities and incident stroke: the Atherosclerosis Risk in Communities Study, Lancet, 358, 1134, 2001.

[79]Cheung, N., Rogers, S., Couper, D.J., et al., Is diabetic retinopathy an independent risk factor for ischemic stroke? Stroke, 38, 398, 2007.

[80]Wong, T.Y., Klein, R., Sharrett, A.R., et al., Cerebral white matter lesions, retinopathy, and incident clinical stroke, JAMA, 288, 67, 2002.

[81]Mitchell, P., Wang, J.J., Wong, T.Y., et al., Retinal microvascular signs and risk of stroke and stroke mortality, Neurology, 65, 1005, 2005.

[82]Cheung, N., Wang, J.J., Klein, R., et al., Diabetic retinopathy and risk of coronary heart disease: The Atherosclerosis Risk in Communities Study, Diabetes Care, 30, 1742, 2007.

[83]Wong, T.Y., Rosamond, W., Chang, P.P., et al., Retinopathy and risk of congestive heart failure, JAMA, 293, 63, 2005.

[84]Wong, T.Y., Coresh, J., Klein, R., et al., Retinal microvascular abnormalities and renal dysfunction: the atherosclerosis risk in communities study, J Am Soc Nephrol, 15, 2469, 2004.

[85]Edwards, M.S., Wilson, D.B., Craven, T.E., et al., Associations between retinal microvascular abnormalities and declining renal function in the elderly population: the Cardiovascular Health Study, Am J Kidney Dis, 46, 214, 2005.

Retinal Vascular Changes as Biomarkers of Systemic Cardiovascular Diseases 213

[86]Leung, H., Wang, J.J., Rochtchina, E., et al., Impact of current and past blood pressure on retinal arteriolar diameter in an older population, J Hypertens, 22, 1543, 2004.

[87]Klein, R., Klein, B.E., Moss, S.E., et al., Retinal vascular abnormalities in persons with type 1 diabetes: the Wisconsin Epidemiologic Study of Diabetic Retinopathy: XVIII, Ophthalmology, 110, 2118, 2003.

[88]Wong, T.Y., Shankar, A., Klein, R., et al., Prospective cohort study of retinal vessel diameters and risk of hypertension, BMJ, 329, 79, 2004.

[89]Smith, W., Wang, J.J., Wong, T.Y., et al., Retinal arteriolar narrowing is associated with 5-year incident severe hypertension: the Blue Mountains Eye Study, Hypertension, 44, 442, 2004.

[90]Wong, T.Y., Klein, R., Sharrett, A.R., et al., Retinal arteriolar narrowing and risk of coronary heart disease in men and women. the Atherosclerosis Risk in Communities Study, JAMA, 287, 1153, 2002.

[91]Mitchell, P., Cheung, N., de Haseth, K., et al., Blood pressure and retinal arteriolar narrowing in children, Hypertension, 49, 1156, 2007.

[92]Ikram, M.K., Witteman, J.C., Vingerling, J.R., et al., Retinal vessel diameters and risk of hypertension: the Rotterdam Study, Hypertension, 47, 189, 2006.

[93]Wong, T.Y., Kamineni, A., Klein, R., et al., Quantitative retinal venular caliber and risk of cardiovascular disease in older persons: the cardiovascular health study, Arch Intern Med, 166, 2388, 2006.

[94]Wang, J.J., Liew, G., Wong, T.Y., et al., Retinal vascular caliber and the risk of coronary heart disease-related mortality, Heart, 2006.

[95]Ikram, M.K., de Jong, F.J., Bos, M.J., et al., Retinal vessel diameters and risk of stroke: the Rotterdam Study, Neurology, 66, 1339, 2006.

[96]Leung, H., Wang, J.J., Rochtchina, E., et al., Relationships between age, blood pressure, and retinal vessel diameters in an older population, Invest Ophthalmol Vis Sci, 44, 2900, 2003.

[97]Sharp, P.S., Chaturvedi, N., Wormald, R., et al., Hypertensive retinopathy in Afro-Caribbeans and Europeans. Prevalence and risk factor relationships, Hypertension, 25, 1322, 1995.

[98]Klein, R., Sharrett, A.R., Klein, B.E., et al., Are retinal arteriolar abnormalities related to atherosclerosis?: the Atherosclerosis Risk in Communities Study, Arterioscler Thromb Vasc Biol, 20, 1644, 2000.

[99]Feihl, F., Liaudet, L., Waeber, B., et al., Hypertension: a disease of the microcirculation? Hypertension, 48, 1012, 2006.

[100]Strachan, M.W. and McKnight, J.A., Images in clinical medicine. improvement in hypertensive retinopathy after treatment of hypertension, N Engl J

Med, 352, e17, 2005.

[101]Bock, K.D., Regression of retinal vascular changes by antihypertensive therapy, Hypertension, 6, III158, 1984.

[102]Dahlof, B., Stenkula, S., and Hansson, L., Hypertensive retinal vascular changes: relationship to left ventricular hypertrophy and arteriolar changes before and after treatment, Blood Press, 1, 35, 1992.

[103]Pose-Reino, A., Rodriguez-Fernandez, M., Hayik, B., et al., Regression of alterations in retinal microcirculation following treatment for arterial hypertension, J Clin Hypertens (Greenwich), 8, 590, 2006.

[104]Wong, T.Y., Is retinal photography useful in the measurement of stroke risk?

Lancet Neurol, 3, 179, 2004.

[105]Okada, H., Horibe, H., Yoshiyuki, O., et al., A prospective study of cerebrovascular disease in Japanese rural communities, Akabane and Asahi. Part

1:evaluation of risk factors in the occurrence of cerebral hemorrhage and thrombosis, Stroke, 7, 599, 1976.

[106]Tanaka, H., Hayashi, M., Date, C., et al., Epidemiologic studies of stroke in Shibata, a Japanese provincial city: preliminary report on risk factors for cerebral infarction, Stroke, 16, 773, 1985.

[107]Svardsudd, K., Wedel, H., Aurell, E., et al., Hypertensive eye ground changes. prevalence, relation to blood pressure and prognostic importance. the study of men born in 1913, Acta Med Scand, 204, 159, 1978.

[108]Wong, T.Y., Klein, R., Sharrett, A.R., et al., Retinal microvascular abnormalities and cognitive impairment in middle-aged persons: the Atherosclerosis Risk in Communities Study, Stroke, 33, 1487, 2002.

[109]Wong, T.Y., Mosley, Jr., T.H., Klein, R., et al., Retinal microvascular changes and MRI signs of cerebral atrophy in healthy, middle-aged people, Neurology, 61, 806, 2003.

[110]Wong, T.Y., Klein, R., Nieto, F.J., et al., Retinal microvascular abnormalities and 10-year cardiovascular mortality: a population-based case-control study, Ophthalmology, 110, 933, 2003.

[111]Kwa, V.I., van der Sande, J.J., Stam, J., et al., Retinal arterial changes correlate with cerebral small-vessel disease, Neurology, 59, 1536, 2002.

[112]Schneider, R., Rademacher, M., and Wolf, S., Lacunar infarcts and white matter attenuation. Ophthalmologic and microcirculatory aspects of the pathophysiology, Stroke, 24, 1874, 1993.

[113]Dozono, K., Ishii, N., Nishihara, Y., et al., An autopsy study of the incidence of lacunes in relation to age, hypertension, and arteriosclerosis, Stroke, 22, 993, 1991.

Retinal Vascular Changes as Biomarkers of Systemic Cardiovascular Diseases 215

[114]Hiroki, M., Miyashita, K., Yoshida, H., et al., Central retinal artery doppler flow parameters reflect the severity of cerebral small-vessel disease, Stroke, 34, e92, 2003.

[115]Wardlaw, J.M., Sandercock, P.A., Dennis, M.S., et al., Is breakdown of the blood-brain barrier responsible for lacunar stroke, leukoaraiosis, and dementia? Stroke, 34, 806, 2003.

[116]Michelson, E.L., Morganroth, J., Nichols, C.W., et al., Retinal arteriolar changes as an indicator of coronary artery disease, Arch Intern Med, 139, 1139, 1979.

[117]Duncan, B.B., Wong, T.Y., Tyroler, H.A., et al., Hypertensive retinopathy and incident coronary heart disease in high risk men, Br J Ophthalmol, 86, 1002, 2002.

[118]Maguire, M.G., Explaining gender differences in coronary heart disease: hunting for clues with the ophthalmoscope, Arch Ophthalmol, 121, 1328, 2003.

[119]Cannon, 3rd, R.O. and Balaban, R.S., Chest pain in women with normal coronary angiograms, N Engl J Med, 342, 885, 2000.

[120]Miettinen, H., Haffner, S.M., Lehto, S., et al., Retinopathy predicts coronary heart disease events in NIDDM patients, Diabetes Care, 19, 1445, 1996.

[121]Klein, B.E., Klein, R., McBride, P.E., et al., Cardiovascular disease, mortality, and retinal microvascular characteristics in type 1 diabetes: Wisconsin Epidemiologic Study of Diabetic Retinopathy, Arch Intern Med, 164, 1917, 2004.

[122]Faglia, E., Favales, F., Calia, P., et al., Cardiac events in 735 type 2 diabetic patients who underwent screening for unknown asymptomatic coronary heart disease: 5-year follow-up report from the Milan Study on Atherosclerosis and Diabetes (MiSAD), Diabetes Care, 25, 2032, 2002.

[123]Giugliano, D., Acampora, R., De Rosa, N., et al., Coronary artery disease in type-2 diabetes mellitus: a scintigraphic study, Diabete Metab, 19, 463, 1993.

[124]Ioannidis, G., Peppa, M., Rontogianni, P., et al., The concurrence of microalbuminuria and retinopathy with cardiovascular risk factors; reliable predictors of asymptomatic coronary artery disease in type 2 diabetes, Hormones (Athens), 3, 198, 2004.

[125]Yoon, J.K., Lee, K.H., Park, J.M., et al., Usefulness of diabetic retinopathy as a marker of risk for thallium myocardial perfusion defects in non-insulin- dependent diabetes mellitus, Am J Cardiol, 87, 456, 2001, a6.

[126]Akasaka, T., Yoshida, K., Hozumi, T., et al., Retinopathy identifies marked restriction of coronary flow reserve in patients with diabetes mellitus, J Am Coll Cardiol, 30, 935, 1997.

[127]Celik, T., Berdan, M.E., Iyisoy, A., et al., Impaired coronary collateral vessel development in patients with proliferative diabetic retinopathy, Clin Cardiol, 28, 384, 2005.

[128]Yoshida, M., Takamatsu, J., Yoshida, S., et al., Scores of coronary calcification determined by electron beam computed tomography are closely related to the extent of diabetes-specific complications, Horm Metab Res, 31, 558, 1999.

[129]Wong, T.Y., Cheung, N., Islam, F.M.A., et al., Microvascular retinopathy is associated with coronary artery calcified plaque: the Multi-Ethnic Study of Atherosclerosis, 2006, unpublished data.

[130]Norgaz, T., Hobikoglu, G., Aksu, H., et al., Retinopathy is related to the angiographically detected severity and extent of coronary artery disease in patients with type 2 diabetes mellitus, Int Heart J, 46, 639, 2005.

[131]Goldin, A., Beckman, J.A., Schmidt, A.M., et al., Advanced glycation end products: sparking the development of diabetic vascular injury, Circulation, 114, 597, 2006.

[132]Klein, R., Klein, B.E., Moss, S.E., et al., The Wisconsin Epidemiologic Study of Diabetic Retinopathy. II. prevalence and risk of diabetic retinopathy when age at diagnosis is less than 30 years, Arch Ophthalmol, 102, 520, 1984.

[133]Klein, R., Klein, B.E., Moss, S.E., et al., Glycosylated hemoglobin predicts the incidence and progression of diabetic retinopathy, JAMA, 260, 2864, 1988.

[134]The Diabetes Control and Complications Trial Research Group, The effect of intensive treatment of diabetes on the development and progression of longterm complications in insulin-dependent diabetes mellitus, N Engl J Med, 329, 977, 1993.

[135]UK Prospective Diabetes Study (UKPDS) Group, Intensive blood-glucose control with sulphonylureas or insulin compared with conventional treatment and risk of complications in patients with type 2 diabetes (UKPDS 33), Lancet, 352, 837, 1998.

[136]Wong, T.Y., Mohamed, Q., Klein, R., et al., Do retinopathy signs in nondiabetic individuals predict the subsequent risk of diabetes? Br J Ophthalmol, 90, 301, 2006.

[137]Wong, T.Y., Duncan, B.B., Golden, S.H., et al., Associations between the metabolic syndrome and retinal microvascular signs: the Atherosclerosis Risk in Communities Study, Invest Ophthalmol Vis Sci, 45, 2949, 2004.

[138]Klein, B.E., Moss, S.E., Klein, R., et al., The Wisconsin Epidemiologic Study of Diabetic Retinopathy. XIII. relationship of serum cholesterol to retinopathy and hard exudate, Ophthalmology, 98, 1261, 1991.

[139]Chew, E.Y., Klein, M.L., Ferris, 3rd, F.L., et al., Association of elevated serum

Retinal Vascular Changes as Biomarkers of Systemic Cardiovascular Diseases 217

lipid levels with retinal hard exudate in diabetic retinopathy. Early Treatment Diabetic Retinopathy Study (ETDRS) Report 22, Arch Ophthalmol, 114, 1079, 1996.

[140]Keech, A., Simes, R.J., Barter, P., et al., Effects of long-term fenofibrate therapy on cardiovascular events in 9795 people with type 2 diabetes mellitus (the FIELD study): randomised controlled trial, Lancet, 366, 1849, 2005.

[141]Wong, T.Y., Klein, R., Islam, F.M., et al., Diabetic retinopathy in a multiethnic cohort in the united states, Am J Ophthalmol, 141, 446, 2006.

[142]Barr, E.L., Wong, T.Y., Tapp, R.J., et al., Is peripheral neuropathy associated with retinopathy and albuminuria in individuals with impaired glucose metabolism? The 1999–2000 AusDiab, Diabetes Care, 29, 1114, 2006.

[143]Wong, T.Y., Klein, R., Sharrett, A.R., et al., Retinal arteriolar narrowing and risk of diabetes mellitus in middle-aged persons, JAMA, 287, 2528, 2002.

[144]Wong, T.Y., Shankar, A., Klein, R., et al., Retinal arteriolar narrowing, hypertension, and subsequent risk of diabetes mellitus, Arch Intern Med, 165, 1060, 2005.

[145]Ikram, M.K., Janssen, J.A., Roos, A.M., et al., Retinal vessel diameters and risk of impaired fasting glucose or diabetes: the Rotterdam Study, Diabetes, 55, 506, 2006.

[146]Wang, J.J., Taylor, B., Wong, T.Y., et al., Retinal vessel diameters and obesity: a population-based study in older persons, Obesity (Silver Spring), 14, 206, 2006.

[147]Cheung, N., Saw, S.M., Islam, F.M.A., et al., Body mass index and retinal vascular caliber in children, Obesity, 15(1), 209, 2007.

[148]Falck, A. and Laatikainen, L., Retinal vasodilation and hyperglycaemia in diabetic children and adolescents, Acta Ophthalmol Scand, 73, 119, 1995.

[149]Nguyen, T.T. and Wong, T.Y., Retinal vascular manifestations of metabolic disorders, Trends Endocrinol Metab, 17, 262, 2006.

[150]Rajala, U., Laakso, M., Qiao, Q., et al., Prevalence of retinopathy in people with diabetes, impaired glucose tolerance, and normal glucose tolerance, Diabetes Care, 21, 1664, 1998.

[151]Singleton, J.R., Smith, A.G., Russell, J.W., et al., Microvascular complications of impaired glucose tolerance, Diabetes, 52, 2867, 2003.

[152]Harris, M.I., Klein, R., Welborn, T.A., et al., Onset of NIDDM occurs at least 4–7 yr before clinical diagnosis, Diabetes Care, 15, 815, 1992.

[153]Cugati, S., Mitchell, P., and Wang, J.J., Do retinopathy signs in non-diabetic individuals predict the subsequent risk of diabetes? Br J Ophthalmol, 90, 928, 2006.

[154]Cheung, N. and Wong, T.Y., Obesity and eye diseases, Survey of Ophthalmology, 2007, forthcoming.

[155]Chavers, B.M., Mauer, S.M., Ramsay, R.C., et al., Relationship between retinal and glomerular lesions in iddm patients, Diabetes, 43, 441, 1994.

[156]Klein, R., Klein, B.E., Moss, S.E., et al., The 10-year incidence of renal insufficiency in people with type 1 diabetes, Diabetes Care, 22, 743, 1999.

[157]Nag, S., Robertson, D.M., and Dinsdale, H.B., Morphological changes in spontaneously hypertensive rats, Acta Neuropathol (Berl), 52, 27, 1980.

[158]Pontremoli, R., Cheli, V., Sofia, A., et al., Prevalence of microand macroalbuminuria and their relationship with other cardiovascular risk factors in essential hypertension, Nephrol Dial Transplant, 10(Suppl 6), 6, 1995.

[159]Liao, D., Wong, T.Y., Klein, R., et al., Relationship between carotid artery stiffness and retinal arteriolar narrowing in healthy middle-aged persons, Stroke, 35, 837, 2004.

[160]Cooper, L.S., Wong, T.Y., Klein, R., et al., Retinal microvascular abnormalities and MRI-defined subclinical cerebral infarction: the Atherosclerosis Risk in Communities Study, Stroke, 37, 82, 2006.

[161]Cheung, N., Bluemke, D.A., Klein, R., et al., Relation of retinal arteriolar caliber to left ventricular mass and remodeling: the Multi-Ethnic Study of Atherosclerosis, 2006.

[162]Tikellis, G., Arnett, D.K., Skelton, T., et al., Retinal arteriolar signs and left ventricular hypertrophy in African-Americans, 2006, unpublished data.

[163]Ikram, M.K., De Jong, F.J., Van Dijk, E.J., et al., Retinal vessel diameters and cerebral small vessel disease: the Rotterdam Scan Study, Brain, 129, 182, 2006.

[164]Klein, R., Klein, B.E., Knudtson, M.D., et al., Are inflammatory factors related to retinal vessel caliber? The Beaver Dam Eye Study, Arch Ophthalmol, 124, 87, 2006.

[165]Rema, M., Mohan, V., Deepa, R., et al., Association of carotid intima-media thickness and arterial stiffness with diabetic retinopathy: the Chennai Urban Rural Epidemiology Study (CURES-2), Diabetes Care, 27, 1962, 2004.

[166]Tamai, K., Matsubara, A., Tomida, K., et al., Lipid hydroperoxide stimulates leukocyte-endothelium interaction in the retinal microcirculation, Exp Eye Res, 75, 69, 2002.

[167]Chester, A.H., Borland, J.A., Buttery, L.D., et al., Induction of nitric oxide synthase in human vascular smooth muscle: interactions between proinflammatory cytokines, Cardiovasc Res, 38, 814, 1998.

[168]Shigematsu, Y., Hamada, M., Mukai, M., et al., Clinical evidence for an asso-

Retinal Vascular Changes as Biomarkers of Systemic Cardiovascular Diseases 219

ciation between left ventricular geometric adaptation and extracardiac target organ damage in essential hypertension, J Hypertens, 13, 155, 1995.

[169]Saitoh, M., Matsuo, K., Nomoto, S., et al., Relationship between left ventricular hypertrophy and renal and retinal damage in untreated patients with essential hypertension, Intern Med, 37, 576, 1998.

[170]Tournier-Lasserve, E., New players in the genetics of stroke, N Engl J Med, 347, 1711, 2002.

[171]Nabel, E.G., Cardiovascular disease, N Engl J Med, 349, 60, 2003.

[172]Kupper, N., Willemsen, G., Riese, H., et al., Heritability of daytime ambulatory blood pressure in an extended twin design, Hypertension, 45, 80, 2005.

[173]McCaffery, J.M., Pogue-Geile, M.F., Debski, T.T., et al., Genetic and environmental causes of covariation among blood pressure, body mass and serum lipids during young adulthood: a twin study, J Hypertens, 17, 1677, 1999.

[174]Lee, K.E., Klein, B.E., Klein, R., et al., Familial aggregation of retinal vessel caliber in the Beaver Dam Eye Study, Invest Ophthalmol Vis Sci, 45, 3929, 2004.

[175]Taarnhoj, N.C., Larsen, M., Sander, B., et al., Heritability of retinal vessel diameters and blood pressure: a twin study, Invest Ophthalmol Vis Sci, 47, 3539, 2006.

[176]Xing, C., Klein, B.E., Klein, R., et al., Genome-wide linkage study of retinal vessel diameters in the Beaver Dam Eye Study, Hypertension, 47, 797, 2006.

[177]Wang, J.J. and Wong, T.Y., Genetic determinants of retinal vascular caliber: additional insights into hypertension pathogenesis, Hypertension, 47, 644, 2006.

[178]Witt, N., Wong, T.Y., Hughes, A.D., et al., Abnormalities of retinal microvascular structure and risk of mortality from ischemic heart disease and stroke, Hypertension, 47, 975, 2006.

[179]Hughes, A.D., Martinez-Perez, E., Jabbar, A.S., et al., Quantification of topological changes in retinal vascular architecture in essential and malignant hypertension, J Hypertens, 24, 889, 2006.

[180]Gould, D.B., Phalan, F.C., van Mil, S.E., et al., Role of COL4A1 in smallvessel disease and hemorrhagic stroke, N Engl J Med, 354, 1489, 2006.

[181]Gekeler, F., Shinoda, K., Junger, M., et al., Familial retinal arterial tortuosity associated with tortuosity in nail bed capillaries, Arch Ophthalmol, 124, 1492, 2006.

[182]Muiesan, M.L. and Grassi, G., Assessment of retinal vascular changes in hypertension: new perspectives, J Hypertens, 24, 813, 2006.