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MSC Neuro 2025 P1

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Cisternalpuncture:BetweenC1and occiput(rare,specialized)

Ventricularpuncture: Neurosurgical,viaskullopening

CSFChangesinPathology

 

 

 

 

Condition

CSF

Protein

Cells

Glucos

Notes

 

Appearance

 

(Pleocytosis

e

 

 

 

 

)

 

 

 

 

 

Tensof

 

 

 

 

 

thousands,

 

Highprotein,

Purulent

Cloudy,

 

mainly

 

very high

meningitis

yellow-green

↑↑

neutrophils

WBCs

 

 

 

 

 

Mildincrease

Serous(viral)

 

 

<100,mainly

 

incellsand

meningitis

Clear

Slight↑

lymphocytes

Normal

protein

 

 

 

 

 

Classic

 

Clear,

 

Hundreds,

 

reduced

Tuberculous

sometimes

↑(1–1.5

mostly

 

glucoseand

meningitis

fibrinfilm

g/L)

lymphocytes

chloride

Brain

Clearor

Markedl

 

 

Protein-cell

tumors/spina

xanthochromi

y↑(5–10

Usually

 

dissociation

ltumors

c

g/L)

unchanged

Normal

syndrome

 

 

 

 

 

RBCsseen

CNS

Bloodyor

 

 

 

microscopicall

hemorrhage

reddish

Variable

Normal

y

 

 

 

 

 

Eosinophils

Parasitic

 

 

 

 

suggest

CNS

Clearor

 

Eosinophils

 

parasitic

infections

cloudy

Variable

present

Variable

infections

LiquorodynamicTests

TestName

Description

Interpretation

 

Manualjugularvein

 

 

compressionduring

 

 

lumbarpunctureto

Normal: rapid,significant

Queckenstedt

observeCSFpressure

pressureriseandreturn;

Test

response

Blockade:noordelayedrise

 

Patientflexesheadto

IncreaseinCSFpressure

 

compresscervicalveins;

followedbynormalizationwith

 

monitoredCSFpressure

headrepositioningindicates

PussepTest

changes

patentsubarachnoidspace

 

Increasedintravertebral

UsedtoassessCSFflowand

StukkayTest

pressuretestedindirectly

blockages

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