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MSC - F. Surgery Answers 2025

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oDifferentiates benign from malignant ulcer based on crater shape and wall involvement.

Duodenal ulcer findings:

oUlcer crater in duodenal bulb (seen “en face”).

o Difficult filling of duodenal bulb due to edema/spasm.

oSecondary signs: mucosal edema, spasm.

5.Endoscopy (Fibroesophagogastroduodenoscopy - FGS)

Most accurate diagnostic method with about 95% diagnostic accuracy.

Flexible fiber-optic instrument allows direct visualization of:

oEsophagus.

o Stomach.

oDuodenum.

Advantages:

oVisual confirmation of ulcer.

o Ability to take biopsies for histological examination.

o Therapeutic interventions possible (e.g., cauterization). o Detection of complications or malignancy.

o Allows photographic documentation.

Summary Table of Diagnostic Tools

 

Diagnostic Tool

Purpose/Utility

Findings in Ulcers

History &

Pain characteristics,

Epigastric tenderness (gastric);

Physical Exam

tenderness location

right hypochondrium (duodenal)

Blood tests

Anemia detection,

Low Hb (bleeding), raised ESR

inflammation marker

(possible malignancy)

 

Diagnostic Tool Purpose/Utility

Stool tests Detect occult bleeding

Gastric

Measure acid production

secretion tests

Findings in Ulcers

Positive occult blood, melena indicates active bleeding

High acid in duodenal ulcer; low acid in gastric ulcer (body)

Barium meal X- Visualize ulcers, differentiate Ulcer crater, spasm, delayed

ray

benign/malignant

emptying, malignant changes

Endoscopy

Direct visualization, biopsy,

Visual confirmation, biopsy for

(FGS)

treatment

malignancy, therapeutic options

4. Surgical treatment of gastric ulcer and duodenal ulcer.

Surgical Treatment of Gastric and Duodenal Ulcers

1.Indications for Surgery

Absolute Indications: o Ulcer perforation

o Profuse gastrointestinal hemorrhage

o Subcompensated and decompensated pyloric stenosis o Ulcer malignancy (malignization)

Conditionally Absolute Indications:

o Ulcer penetration

o Recurrent gastrointestinal hemorrhage

oCompensated stenosis of pyloroduodenal area

Relative Indications:

oUnsuccessful conservative therapy

o Frequent ulcer relapses o Multiple ulcers

oReduced working ability (especially with dual localization)

2.Preoperative Preparation

Thorough examination

Anti-ulcer therapy

Correction of water-electrolyte and protein metabolism disorders

Treatment of comorbidities

3.Surgical Methods

A.Gastric Resection

Operation of choice for gastric ulcer

Typically resection of 2/3 of the stomach to remove the ulcer and acidproducing areas

Anastomosis options:

o Bilroth I: Gastroduodenal end-to-end anastomosis (preferred)

oBilroth II: Gastric stump anastomosed to jejunum if gastroduodenal anastomosis is impossible (e.g., scar tissue, periduodenitis)

oTechniques to prevent duodenal reflux (e.g., Balfour, Rhu techniques)

B. Vagotomy (aimed at reducing gastric acid secretion)

Reduces acid secretion by cutting vagus nerve branches that stimulate acid production

Allows spontaneous healing of duodenal ulcers due to decreased acidity

Three types of vagotomy:

1.Truncal Vagotomy:

Transects vagal trunks in thoracic and upper abdominal regions

Denervates stomach and other abdominal organs → may cause complications (e.g., cholecystitis, pancreatitis, diarrhea)

Gastric motor activity impaired → requires a draining operation

(e.g., pyloroplasty or gastrojejunostomy)

Draining operations after truncal vagotomy:

Pyloroplasty:

Heineke–Mikulicz

Finney

Gastrointestinal anastomosis:

Gastrojejunostomy

Jaboulay’s gastroduodenostomy

Transverse gastroduodenal anastomosis

Partial gastric resection may also be done

2.Selective Vagotomy:

Cuts only vagus branches to the stomach; spares branches to liver and celiac plexus

Denervates whole stomach → motor function impaired, so draining operation needed

3.Selective Proximal Vagotomy (SPV):

Cuts vagal branches to acid-producing regions (lesser curvature and fundus)

Preserves antral innervation → maintains gastric motility

Can be done without draining procedure

Less functional disturbance, fewer complications

Relapse rate after vagotomy: ~16%, depending on completeness

C.Antrectomy

Excision of the antrum (gastrin-producing part)

Anastomosis of stomach remnant to jejunum (usually)

Reduces gastric acid secretion by removing gastrin source

4.Postoperative Care

Intensive infusion therapy for 3-5 days (fluids, proteins, blood transfusion if needed)

Drugs to stimulate gastric and intestinal motility (ganglionic blockers, proserin)

Nasogastric drainage to prevent gastrostasis

Gradual feeding after recovery of GI function

Exercise therapy

Summary Table of Main Surgical Options

Procedure

Truncal

Vagotomy

Selective

Vagotomy

Selective

Proximal

Vagotomy

Partial

Gastrectomy

(Bilroth I/II)

Antrectomy

Description

Effect on Acid

Need for Draining

Secretion

Procedure

 

Cut vagal trunks, denervates stomach & organs

Cut vagal branches to stomach only

Cut vagal branches to acid-producing area only

Remove 2/3 stomach + anastomosis

Remove antrum (gastrin source)

Significantly

Yes (pyloroplasty or

reduces acid

gastrojejunostomy)

Reduces acid

Yes

Reduces acid,

 

preserves

No

motility

 

Removes acid-

Variable depending on

producing tissue

anastomosis

Reduces acid

Usually yes

5. Perforated stomach ulcer and duodenal ulcer. Clinical picture.

A perforated ulcer is a serious complication where an untreated peptic ulcer erodes through the wall of the stomach or duodenum, leading to the leakage of gastric or duodenal contents into the peritoneal cavity and causing peritonitis.

Incidence

Occurs in approximately 7% of ulcer patients.

Around 20% of cases occur in patients with silent ulcers (no previous symptoms).

Types of Perforation

1.Open (free) perforation – Contents escape freely into the abdominal cavity.

2.Concealed (sealed) perforation – The perforation is covered by fibrin, omentum, or adjacent organs.

Clinical Stages of Open Perforation

Stage I: Primary Shock (First 3–6 hours)

Sudden, severe epigastric pain ("knife-like").

Pain spreads to the whole abdomen, especially the right side.

Radiates to shoulder or scapular region (phrenic nerve irritation).

Rigid abdomen ("wooden belly"), positive peritoneal signs.

Vitals: Bradycardia (50–60 bpm) or mild tachycardia (80–90 bpm), low BP.

Signs: Pale face, cold sweat, hypopnea, tachypnea.

Percussion: Absence of liver dullness (free gas in peritoneum).

X-ray: Free gas under the diaphragm in 75–80% of cases.

Stage II: “Sham Well-being” (6–12 hours)

Dilution of acidic content by exudate reduces pain temporarily.

Misleading clinical improvement: patient feels better.

However, peritonitis and toxic symptoms increase (tachycardia, leukocytosis).

Careful monitoring, lab, imaging, or laparoscopy is essential to avoid misdiagnosis.

Stage III: Diffuse Peritonitis (>12 hours)

Generalized peritonitis: high fever, tachycardia, vomiting, oliguria.

Enteroparesis, abdominal distension, hypotension, collapse.

Requires urgent surgical intervention.

Concealed (Sealed) Perforation

The ulcer is covered by omentum, liver, or fibrin.

Symptoms less severe than open perforation.

Pain becomes localized, often in epigastrium or right hypochondrium.

Perforation into omental bursa: causes pain radiating to the right iliac region.

No free gas, liver dullness is preserved.

Diagnosis depends on:

o FGS (Fibrogastroscopy)

oLaparoscopy

6.Diagnosis and treatment tactics in perforated gastric ulcer and duodenal ulcer.

Diagnosis

Clinical signs: Sudden epigastric pain, rigid abdomen, peritoneal signs.

X-ray abdomen (upright): Free gas under diaphragm.

Percussion: Disappearance of liver dullness.

Laparoscopy: Especially useful in concealed or posterior wall perforations.

Laboratory tests: May be normal initially; leukocytosis develops later.

Treatment

Preoperative Preparation

Depends on the duration and severity of peritonitis.

Includes intensive IV fluids, antibiotics, gastric decompression, and electrolyte correction.

Surgical Options

1.Simple Closure (Suture or Omental Patch)

Indicated in early stage (within 6 hours), when perforation is small and patient is unstable or unsuitable for radical surgery.

Graham patch (omentopexy): when ulcer edges are edematous or inflamed.

2.Radical Surgery

Indicated if:

o Ulcer is chronic or large.

o Patient is stable and within early time window.

oPerforation is part of active ulcer disease requiring definitive treatment.

Procedures include:

oGastric resection

o Vagotomy + ulcer excision + drainage procedure

Postoperative Care

Focuses on:

o Detoxification

o Treatment of peritonitis

o Prevention of complications (e.g., ileus, infections)

o Nutritional and fluid support

o Use of NG tube for decompression

o Gradual reintroduction of oral feeding after GI function restoration

Key Points

Perforated ulcer is a surgical emergency.

Clinical presentation may vary depending on perforation type.

Early diagnosis and prompt surgery improve prognosis.

In selected cases, definitive surgery (vagotomy/resection) can be performed.

Laparoscopy is valuable for diagnosis and even treatment in experienced hands.

7.Treatment of perforated gastric ulcer and duodenal ulcer.

It’s the same answer as previous the loosu *oodhi

8. Differential diagnosis of perforated gastric ulcer and acute pancreatitis.

Feature

Onset of Pain

Pain Location

Pain Radiation

Patient’s

Position

Perforated Gastric/Duodenal Acute Pancreatitis

Ulcer

Sudden, abrupt ("knife-like")

Epigastric, quickly spreads to whole abdomen

Supraclavicular or scapular (phrenic nerve)

Lies still (to avoid pain) with knees drawn

Gradual or sudden

Epigastric, radiates to back ("belt-like")

Back, flanks

Leans forward to relieve pain

Feature

Facial

Expression

Peritoneal Signs

Abdominal

Rigidity

Bowel Sounds

Vomiting

Fever

Shock

Laboratory

Findings

X-ray Abdomen

US/CT Scan

FGS (Endoscopy)

Definitive

Diagnosis

Perforated Gastric/Duodenal

Ulcer

Pale, frightened, cold sweat

Marked: "wooden belly", rebound tenderness

Severe, generalized

Absent (due to paralytic ileus)

Usually occurs after pain onset

Develops in stage III (peritonitis)

Early in severe cases (due to perforation)

Initially normal; later leukocytosis

Free gas under diaphragm (in 75–80%)

May show free fluid, perforation

May show ulcer (posterior or anterior wall)

X-ray (free gas), laparoscopy

Treatment

Emergency surgery

Acute Pancreatitis

Pale, anxious, sweating

Mild to moderate (in severe cases)

Usually mild

Decreased or absent

Often precedes pain

Mild to moderate early on

Later stages due to systemic inflammation

Elevated serum amylase, lipase, leukocytosis

No free gas

Pancreatic inflammation, edema, pseudocyst

Not used acutely

Serum enzymes, CT abdomen

Conservative (fluids, analgesics, enzymes, ICU care)

Important Laboratory Markers