
MSC - F. Surgery Answers 2025
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oDifferentiates benign from malignant ulcer based on crater shape and wall involvement.
Duodenal ulcer findings:
oUlcer crater in duodenal bulb (seen “en face”).
o Difficult filling of duodenal bulb due to edema/spasm.
oSecondary signs: mucosal edema, spasm.
5.Endoscopy (Fibroesophagogastroduodenoscopy - FGS)
Most accurate diagnostic method with about 95% diagnostic accuracy.
Flexible fiber-optic instrument allows direct visualization of:
oEsophagus.
o Stomach.
oDuodenum.
Advantages:
oVisual confirmation of ulcer.
o Ability to take biopsies for histological examination.
o Therapeutic interventions possible (e.g., cauterization). o Detection of complications or malignancy.
o Allows photographic documentation.
Summary Table of Diagnostic Tools |
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Diagnostic Tool |
Purpose/Utility |
Findings in Ulcers |
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History & |
Pain characteristics, |
Epigastric tenderness (gastric); |
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Physical Exam |
tenderness location |
right hypochondrium (duodenal) |
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Blood tests |
Anemia detection, |
Low Hb (bleeding), raised ESR |
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inflammation marker |
(possible malignancy) |
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Diagnostic Tool Purpose/Utility
Stool tests Detect occult bleeding
Gastric
Measure acid production
secretion tests
Findings in Ulcers
Positive occult blood, melena indicates active bleeding
High acid in duodenal ulcer; low acid in gastric ulcer (body)
Barium meal X- Visualize ulcers, differentiate Ulcer crater, spasm, delayed
ray |
benign/malignant |
emptying, malignant changes |
Endoscopy |
Direct visualization, biopsy, |
Visual confirmation, biopsy for |
(FGS) |
treatment |
malignancy, therapeutic options |
4. Surgical treatment of gastric ulcer and duodenal ulcer.
Surgical Treatment of Gastric and Duodenal Ulcers
1.Indications for Surgery
Absolute Indications: o Ulcer perforation
o Profuse gastrointestinal hemorrhage
o Subcompensated and decompensated pyloric stenosis o Ulcer malignancy (malignization)
Conditionally Absolute Indications:
o Ulcer penetration
o Recurrent gastrointestinal hemorrhage
oCompensated stenosis of pyloroduodenal area
Relative Indications:
oUnsuccessful conservative therapy
o Frequent ulcer relapses o Multiple ulcers

oReduced working ability (especially with dual localization)
2.Preoperative Preparation
Thorough examination
Anti-ulcer therapy
Correction of water-electrolyte and protein metabolism disorders
Treatment of comorbidities
3.Surgical Methods
A.Gastric Resection
Operation of choice for gastric ulcer
Typically resection of 2/3 of the stomach to remove the ulcer and acidproducing areas
Anastomosis options:
o Bilroth I: Gastroduodenal end-to-end anastomosis (preferred)
oBilroth II: Gastric stump anastomosed to jejunum if gastroduodenal anastomosis is impossible (e.g., scar tissue, periduodenitis)
oTechniques to prevent duodenal reflux (e.g., Balfour, Rhu techniques)
B. Vagotomy (aimed at reducing gastric acid secretion)
Reduces acid secretion by cutting vagus nerve branches that stimulate acid production
Allows spontaneous healing of duodenal ulcers due to decreased acidity
Three types of vagotomy:
1.Truncal Vagotomy:
Transects vagal trunks in thoracic and upper abdominal regions
Denervates stomach and other abdominal organs → may cause complications (e.g., cholecystitis, pancreatitis, diarrhea)

Gastric motor activity impaired → requires a draining operation
(e.g., pyloroplasty or gastrojejunostomy)
Draining operations after truncal vagotomy:
Pyloroplasty:
Heineke–Mikulicz
Finney
Gastrointestinal anastomosis:
Gastrojejunostomy
Jaboulay’s gastroduodenostomy
Transverse gastroduodenal anastomosis
Partial gastric resection may also be done
2.Selective Vagotomy:
Cuts only vagus branches to the stomach; spares branches to liver and celiac plexus
Denervates whole stomach → motor function impaired, so draining operation needed
3.Selective Proximal Vagotomy (SPV):
Cuts vagal branches to acid-producing regions (lesser curvature and fundus)
Preserves antral innervation → maintains gastric motility
Can be done without draining procedure
Less functional disturbance, fewer complications
Relapse rate after vagotomy: ~16%, depending on completeness
C.Antrectomy
Excision of the antrum (gastrin-producing part)
Anastomosis of stomach remnant to jejunum (usually)

Reduces gastric acid secretion by removing gastrin source
4.Postoperative Care
Intensive infusion therapy for 3-5 days (fluids, proteins, blood transfusion if needed)
Drugs to stimulate gastric and intestinal motility (ganglionic blockers, proserin)
Nasogastric drainage to prevent gastrostasis
Gradual feeding after recovery of GI function
Exercise therapy
Summary Table of Main Surgical Options
Procedure
Truncal
Vagotomy
Selective
Vagotomy
Selective
Proximal
Vagotomy
Partial
Gastrectomy
(Bilroth I/II)
Antrectomy
Description |
Effect on Acid |
Need for Draining |
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Secretion |
Procedure |
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Cut vagal trunks, denervates stomach & organs
Cut vagal branches to stomach only
Cut vagal branches to acid-producing area only
Remove 2/3 stomach + anastomosis
Remove antrum (gastrin source)
Significantly |
Yes (pyloroplasty or |
reduces acid |
gastrojejunostomy) |
Reduces acid |
Yes |
Reduces acid, |
|
preserves |
No |
motility |
|
Removes acid- |
Variable depending on |
producing tissue |
anastomosis |
Reduces acid |
Usually yes |
5. Perforated stomach ulcer and duodenal ulcer. Clinical picture.

A perforated ulcer is a serious complication where an untreated peptic ulcer erodes through the wall of the stomach or duodenum, leading to the leakage of gastric or duodenal contents into the peritoneal cavity and causing peritonitis.
Incidence
Occurs in approximately 7% of ulcer patients.
Around 20% of cases occur in patients with silent ulcers (no previous symptoms).
Types of Perforation
1.Open (free) perforation – Contents escape freely into the abdominal cavity.
2.Concealed (sealed) perforation – The perforation is covered by fibrin, omentum, or adjacent organs.
Clinical Stages of Open Perforation
Stage I: Primary Shock (First 3–6 hours)
Sudden, severe epigastric pain ("knife-like").
Pain spreads to the whole abdomen, especially the right side.
Radiates to shoulder or scapular region (phrenic nerve irritation).
Rigid abdomen ("wooden belly"), positive peritoneal signs.
Vitals: Bradycardia (50–60 bpm) or mild tachycardia (80–90 bpm), low BP.
Signs: Pale face, cold sweat, hypopnea, tachypnea.
Percussion: Absence of liver dullness (free gas in peritoneum).
X-ray: Free gas under the diaphragm in 75–80% of cases.
Stage II: “Sham Well-being” (6–12 hours)
Dilution of acidic content by exudate reduces pain temporarily.
Misleading clinical improvement: patient feels better.

However, peritonitis and toxic symptoms increase (tachycardia, leukocytosis).
Careful monitoring, lab, imaging, or laparoscopy is essential to avoid misdiagnosis.
Stage III: Diffuse Peritonitis (>12 hours)
Generalized peritonitis: high fever, tachycardia, vomiting, oliguria.
Enteroparesis, abdominal distension, hypotension, collapse.
Requires urgent surgical intervention.
Concealed (Sealed) Perforation
The ulcer is covered by omentum, liver, or fibrin.
Symptoms less severe than open perforation.
Pain becomes localized, often in epigastrium or right hypochondrium.
Perforation into omental bursa: causes pain radiating to the right iliac region.
No free gas, liver dullness is preserved.
Diagnosis depends on:
o FGS (Fibrogastroscopy)
oLaparoscopy
6.Diagnosis and treatment tactics in perforated gastric ulcer and duodenal ulcer.
Diagnosis
Clinical signs: Sudden epigastric pain, rigid abdomen, peritoneal signs.
X-ray abdomen (upright): Free gas under diaphragm.
Percussion: Disappearance of liver dullness.
Laparoscopy: Especially useful in concealed or posterior wall perforations.

Laboratory tests: May be normal initially; leukocytosis develops later.
Treatment
Preoperative Preparation
Depends on the duration and severity of peritonitis.
Includes intensive IV fluids, antibiotics, gastric decompression, and electrolyte correction.
Surgical Options
1.Simple Closure (Suture or Omental Patch)
Indicated in early stage (within 6 hours), when perforation is small and patient is unstable or unsuitable for radical surgery.
Graham patch (omentopexy): when ulcer edges are edematous or inflamed.
2.Radical Surgery
Indicated if:
o Ulcer is chronic or large.
o Patient is stable and within early time window.
oPerforation is part of active ulcer disease requiring definitive treatment.
Procedures include:
oGastric resection
o Vagotomy + ulcer excision + drainage procedure
Postoperative Care
Focuses on:
o Detoxification
o Treatment of peritonitis

o Prevention of complications (e.g., ileus, infections)
o Nutritional and fluid support
o Use of NG tube for decompression
o Gradual reintroduction of oral feeding after GI function restoration
Key Points
Perforated ulcer is a surgical emergency.
Clinical presentation may vary depending on perforation type.
Early diagnosis and prompt surgery improve prognosis.
In selected cases, definitive surgery (vagotomy/resection) can be performed.
Laparoscopy is valuable for diagnosis and even treatment in experienced hands.
7.Treatment of perforated gastric ulcer and duodenal ulcer.
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8. Differential diagnosis of perforated gastric ulcer and acute pancreatitis.
Feature
Onset of Pain
Pain Location
Pain Radiation
Patient’s
Position
Perforated Gastric/Duodenal Acute Pancreatitis
Ulcer
Sudden, abrupt ("knife-like")
Epigastric, quickly spreads to whole abdomen
Supraclavicular or scapular (phrenic nerve)
Lies still (to avoid pain) with knees drawn
Gradual or sudden
Epigastric, radiates to back ("belt-like")
Back, flanks
Leans forward to relieve pain

Feature
Facial
Expression
Peritoneal Signs
Abdominal
Rigidity
Bowel Sounds
Vomiting
Fever
Shock
Laboratory
Findings
X-ray Abdomen
US/CT Scan
FGS (Endoscopy)
Definitive
Diagnosis
Perforated Gastric/Duodenal
Ulcer
Pale, frightened, cold sweat
Marked: "wooden belly", rebound tenderness
Severe, generalized
Absent (due to paralytic ileus)
Usually occurs after pain onset
Develops in stage III (peritonitis)
Early in severe cases (due to perforation)
Initially normal; later leukocytosis
Free gas under diaphragm (in 75–80%)
May show free fluid, perforation
May show ulcer (posterior or anterior wall)
X-ray (free gas), laparoscopy
Treatment |
Emergency surgery |
Acute Pancreatitis
Pale, anxious, sweating
Mild to moderate (in severe cases)
Usually mild
Decreased or absent
Often precedes pain
Mild to moderate early on
Later stages due to systemic inflammation
Elevated serum amylase, lipase, leukocytosis
No free gas
Pancreatic inflammation, edema, pseudocyst
Not used acutely
Serum enzymes, CT abdomen
Conservative (fluids, analgesics, enzymes, ICU care)
Important Laboratory Markers