Цервікальна карцинома
Endometritis
Endometrial
polyp
Acut
e
Chroni
c
Bacterial infection after delivery or miscarriage
Intrauterine contraceptive devices Tuberculosis (from tuberculous salpingitis) Retained gestation tissue
Chronic pelvic inflammatory disease
Endometrium
- Elongated shape -Vascular pedicle (arrowhead)
-Cystic glands -Covered by glandular epithelium
Endometrial
hyperplasia
Associated with prolonged estrogenic stimulation |
Endometrium |
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of the endometrium |
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Obesity |
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Menopause |
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Polycystic ovarian syndrome |
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- Functioning granulosa cell tumors of the ovary
- Excessive ovarian cortical function (cortical stromal hyperplasia) - Estrogen replacement therapy
Карцинома тіла матки
PATHOGENESIS |
FACTORS OF RISK |
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PREMENOPAUSE |
--AGE |
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ANOVULATIVE |
- DISBALANCE OF ESTROGENS |
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CIRCLES |
- |
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--HEREDITARY;; |
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ABSENT OF |
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--EARLY MENARCHE |
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YELLOW BODY |
AND LATE MENOPAUSE;; |
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- OBESITY, |
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, |
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--DIABETES MELLITUS,, |
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HYPO- |
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-- HYPERTENSION.. |
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PROGESTE- |
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HYPER- RONEMIA
ESTROGENEMIA
Карцинома тіла матки
Endometriosi s/ adenomyosis
Endometrial glands and stroma outside of the Endometrium endometrium/uterus
Most common site: |
Theories: |
Results in: |
Abdominal cavity |
Regurgitation, |
dysmenorrhea, |
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metaplasia, Mts, |
pelvic pain, |
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stem cell origin |
infertility |
“Chocolate” cyst Of the ovarium
within myometrium irregular nests of endometrial stroma with/without glands, separated from the basalis by at least 2-3 mm
Leiomyoma
Leiomyosarc
oma
Myometrium
The tumors cells are regular in size/shape, elongated with
eosinophilic cytoplasm and form whorled (fascicular) pattern of smooth muscle bundles separated by well vascularized connective tissue/hyalinosis
The tumors cells are irregular in size and have hyperchromatic nuclei, multiple mitotic figures (arrows)
Myometrium
Subserous leiomyomata
Intramural leiomyomata
Submucous leiomyomata
(abnormal bleeding)
Патологія грудної залози
Mastitis
Acut |
-Infection (Staphylococcus aureus most common organism ) or inflammation |
e |
of breast tissue, usually bacterial, often seen in association with lactation |
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-Microscopically: mixed dense inflammatory infiltrate (predominantly |
neutrophils)
Lymphocytic mastopathy (Sclerosing lymphocytic lobulitis)
Granulomatou s mastitis
-Manifestation of systemic granulomatous diseases (sarcoidosis, tuberculosis) /
-Causative agent is Corynebacteria (rare).
Nonproliferative breast |
Cysts |
Fibrosi |
Adenosi |
changes |
s |
s |
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(Fibrocystic changes) |
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Epithelial hyperplasia / |
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atypical ductal/lobular |
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Proliferative breast disease |
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hyperplasia* |
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without/with* atypia |
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Sclerosing |
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Papilloma adenosis
