* Drugs affecting the central nervous system *2*44*4*

#253

*!Complex preparations used for neuroleptanalgesy is

*diazepam fentanyl

*++droperidol fentanyl

*diazepam morphine hydrochloride

*nitrazepam fentanyl

*nitrazepam naloxone

#254

*!Drug used for the relief pain in myocardial infarction is

*++morphine

*diazepam

*acetylsalicylic acid

*phenazepam

*mezapam

#255

*!Hypnotic having the least effect the REM-sleep phase is

*++diazepam

*phenobarbital

*valerian tincture

*motherwort tincture

*sodium bromide

#256

*!Opioid analgesic stimulates smooth muscles of internal organs, causes euphoria, by repeated use causes tolerance and drug dependence. The size of the pupil has little effect.

Such preparation is

*omnopon

*++promedol

*fentanyl

*morphine

*ketorolac

#257

*!The drug causes sedative, hypnotic and anticonvulsant effects. It has a pronounced effect on the phase of REM-sleep.

Such preparation is

*++phenobarbital

*diazepam

*phenazepam

*nitrazepam

*zopiclone

#258

*!Preparation of nonnarcotic analgesics of central action having analgesic and antipyretic effect is

*acetylsalicylic acid

*zopiclone

*ketorolac

*analginum

*++paracetamol

#259

*!Non-narcotic analgesics, has anti-inflammatory, antipyretic and analgesic effects, can cause agranulocytosis and aplastic anemia. Such preparation is

*acetylsalicylic acid

*paracetamol

*zopiclone

*++analginum

*ketorolac

#260

*!The preparation reduces the synthesis of prostaglandins in the central nervous system, has analgesic and antipyretic effect, anti-inflammatory effect is almost absent.

Such preparation is

*acetylsalicylic acid

*analginum

*++morphine

*paracetamol

*promedol

#261

*!The preparation is used to prevent the big seizures, focal epilepsy. It has antiarrhythmic action. It can cause proliferation of the mucous membrane of the gums.

Such preparation is

*++diphenin

*ethosuximide

*lamotrigine

*sodium valproate

*carbamazepine

#262

*!To anticonvulsants strong depressed respiration relates

*morphine

*tramadol

*diazepam

*++magnesium sulfate

*sodium hydroxybutyrate

#263

*!Basic principles of treatment of hypnotics acute poisoning include the appointment of

*++analeptics

*M - cholinomimetics

*M - cholinoblockers

*anticholinesterases

*antihistamines

#264

*!Mechanism of analgesic action of morphine is

*blockade of peripheral sensory receptors

*inhibition of prostaglandin synthesis in peripheral tissues

*++interaction with opioid receptors and their stimulation

*blockade of ganglia of sympathetic and parasympathetic nervous system

*interaction with benzodiazepine receptors

#265

*!Mechanism of analgesic action of non-narcotic analgesics is related with the blockade of

*opioid receptors

*++cyclooxygenase

*phospholipase

*motor neurons of the spinal cord

*CNS dopamine receptors

#266

*!The difference narcotic analgesics from the nonnarcotic analgesics is

*suppress pain sensitivity

*do not affect other kinds of sensitivity

*are effective in resorptive action

*do not turn off the consciousness

*++depress respiration

#267

*!Narcotic analgesics having the highest analgesic activity and short duration of action is

*morphine

*promedol

*naloxone

*omnopon

*++fentanyl

#268

*!Effect of ethanol used in the practical medicine is

*narcotic

*hypnotic

*sedative

*++antiseptic

*anti-inflammatory

#269

*!Non-narcotic analgesic of central action the most widely used as an antipyretic is

*analginum

*indomethacin

*acetylsalicylic acid

*++paracetamol

*diclofenac sodium

#270

*!Non-opioid analgesics predominantly peripheral action are indicated in

*++headaches

*bronchospasm

*intestinal atony

*pain in malignant tumors

*traumatic pain

#271

*!Undesirable effect of hypnotics group of barbiturates is

*++violation of sleep structure

*nephrotoxicity

*ototoxicity

*hepatotoxicity

*increased blood pressure

#272

*!The preparation of choice for the treatment of acute intoxication with narcotic analgesics is

*++naloxone

*tramadol

*bemegride

*diazepam

*pentazocin

#273

*!Ethanol in medicinal practice mainly used as

*analeptic

*absorbent

*local anesthetic

*anticonvulsant

*++disinfectant

#274

*!The main mechanism of anti-inflammatory action of non-narcotic analgesics is

*inhibition Na , K-ATPase of cardiomyocyte membrane

*inhibition of monoamine oxidase

*inhibition of cholinesterase

*inhibition of phospholipase A2

*++inhibition of cyclooxygenase

#275

*!To avoid ulcerogenic effect of acetylsalicylic acid is used

*++mucus from starch

*ammonia solution

*menthol

*morphine

*promedol

#276

*!Contraindication to the use of aspirin is

*arterial hypertension

*++peptic ulcer

*myocardial infarction

*hypoacid gastritis

*angina pectoris

#277

*!For acute morphine poisoning the following effect is characterized

*tachycardia

*++pupillary constriction

*increased blood pressure

*respiratory stimulation

*relaxation of bronchi

#278

*!Mechanism of analgesic action of narcotic analgesics is associated with

*++action on opioid receptors

*inhibition of prostaglandin synthesis

*blocking formation of pain impulses

*blocking phospholipase

*decrease synthesis of leukotrienes

#279

*!Narcotic analgesic with the highest analgesic activity and short duration of action is

  *morphine

*++fentanyl

*promedol

  *omnopon

*naloxone

#280

*!Preparation used in falling asleep is

*++ caffeine

*diazepame

*carbamazepine

*diphenine

*ethosuximide

#281

*!Hypnotic the application of which often develops the deficit phase of REM-sleep is

*++phenobarbital

*nitrazepame

*diazepame

*valerian tincture

*phenazepame

#282

*!The concentration of ethyl alcohol for disinfection of surgical instruments is

*till 12%

*30 - 40%

*70%

*++95 %

*20%

#283

*!Analgesic having anti-inflammatory effect is

*morphine

++acetylsalicylic acid

*tramadol

*pentazoсine

*promedol

#284

*!Non-narcotic analgesics providing analgesic and antipyretic action practically without of anti-inflammatory action is

*acetylsalicylic acid

*++paracetamol

*analginum

*promedol

*omnopon

#285

*!Means used for pulmonary edema are

*adrenomimetics

*M-cholinoblockers

*astringents

*beta-adrenoblockers

*++narcotic analgesics

#286

*!The main symptom of acute morphine poisoning is

*++miosis

*visual disturbances

*tinnitus

*dry mouth

*extrapyramidal disorders

#287

*!Antiepileptic drug reducing the activity of the glutamatergic system is

*sodium valproate

*diazepame

*phenobarbital

*ethosuximide

*++lamotrigine

#288

*!Antiepileptic drug which promotes the accumulation of gamma-aminobutyric acid is

*++phenobarbital

*ethosuximide

*diphenine

*carbamazepine

*lamotrigine

#289

*The drug from group of antidepressants which has antidepressant and psychostimulant action is

*levodopa

*zopiclone

*cordiamine

*mebicar

*imipramine

#290

*!Antidepressant which selectively inhibits MAO-A. It has less pronounced side effects. Such preparation is

*caffeine

*nialamide

*zopiclone

*moclobemide

*amitriptyline

#291

*!Analeptic of direct type of action, directly stimulates respiratory and vasomotor centers. Side effects are manifested by nausea, vomiting, convulsions, muscle twitching. Such drug is

*imipramine

*mebicar

*morphine

*bemegride

*droperidol

#292

*!Analeptic with psychostimulant effect is

*morphine

*caffeine

*tramadol

*triazolam

*risperidone

#293

*!Anxiolytic without sedative action is

  *diazepame

  *buspirone

  *bemegride

  *promedol

  *mebicar

#294

*!The drugs used in psychoses, they can cause extrapyramidal disorders. Such drugs are

*adrenomimetics

*analeptics

*astringents

*anti-Parkinsonians

*neuroleptics

#295

*!Antiparkinsonian agent - an immediate precursor of dopamine is

*levodopa

*selegiline

*bromocriptine

*cyclodol

*omnopon

#296

*!Antipsychotic agent used for neuroleptanalgesia is

*aminazine

*diazepame

*haloperidol

*ethosuximide

*droperidol