*Drugs affecting metabolic processes *2*42*3*

#348

*!Pharmacologic effect of acetylsalicylic acid is

  *sedative

  *++antipyretic

  *hypnotic

  *broncholytic

  *anxiolytic

#349

*!Glucocorticoid used by inhalation in bronchial asthma is

  *hydrocortisone

  *dexamethasone

  *diclofenac sodium

 *++beclomethasone dipropionate

  *prednisolone

#350

*!Glucocorticosteroid poorly absorbed through the skin and mucous membranes is

  *++beclomethasone dipropionate

  *prednisolone

  *dexamethasone

 *flumethasone pivalate

  *hydrocortisone

#351

*!Glucocorticoids cause

*hypercalcemia

*inhibition of protein synthesis

*decrease of blood glucose

*++stimulation of protein synthesis

*hyperkalihisty

#352

*!Specific disease in case of insufficient vitamin C is

  *++scurvy

  *rheumatism

  *pancreatitis

  * pyelonephritis

  *gastritis

#353

*!Nonsteroid antiinflammatory drug having a high activity and little side effects is

  *indomethacin

  *butadione

  *morphine

  *++diclofenac sodium

  *acetylsalicylic acid

#354

*!Corticosteroids do not abrupt discontinued due to

*suppression of the psyche

*falling in blood pressure

*the development of hyperglycemia

*++adrenal insufficiency

*osteoporosis

#355

*!Violation of neuromuscular transmission due to a lack of is

*nicotinic acid

*riboflavin

*folic acid

*ascorbic acid

*++thiamine

#356

*!The mechanism of anti-inflammatory action of non-steroid preparations is associated with inhibition of

  *++enzyme cyclooxygenase

  *enzyme phospholipase

  *enzyme monoamine oxidase

  *enzyme katecholortometiltransferase

  *cholinesterase

#357

*!Indication for use of dimedrol are

  *osteoporosis

  *++ allergic reactions

  *atherosclerosis

  *neuritis

  *hypochromic anemia

#358

*!Side effect of ascorbic acid is

*++inhibition of the function of insular apparatus

*decreasing the acidity of urine

*increasing lipid peroxidation

*increasing the permeability of vascular wall

*hepatotoxic

#359

*!The pharmacological effect of glucocorticoids is

*bronchospastic

*sedative

*immunostimulatory

*++antiallergic

*hypnotic

#360

*!Fluorinated derivative of prednisolone of long-term systemic action is

*beclomethasone dipropionate

*dimedrol

*dexamethasone

*flumethasone pivalate

*hydrocortisone

#361

*!Pyridoxine significantly reduces the toxic effect of

*++anti-TB drugs

*M-cholinomimetics

*analgesics

*anticholinesterases

*local anesthetics

#362

*!Vitamin preparation which has antioxidant properties is

  *riboflavin

  *vikasol

  *thiamine bromide

  *cyanocobalamine

 *++ascorbic acid

#363

*!Vitamin preparation reducing the permeability of vascular wall is

  *retinol

  *tocopherol

  *pyridoxine

  *ergocalciferol

 *++ascorbic acid

#364

*!Vitamin preparation used to improve the dark adaptation of the eye is

  *ergocalciferol

  *++retinol acetate

*cyanocobalamine

*nicotinic acid

  *folic acid

#365

*!Vitamin preparation increasing the synthesis of prothrombin and proconvertin in the liver is

*riboflavin

*ergocalciferol

*tocopherol

*retinol

*++vikasol

#366

*!Vitamin preparation - synergist of ascorbic acid is

*++rutin

*riboflavin

*thiamine bromide

*cyanocobalamine

*pyridoxine

#367

*!When hypervitaminosis D is possible

*bronchospasm

*++deposition of calcium in the kidneys, blood vessels

*damage islet apparatus of pancreas

*later imperforate fontanelles in children

*the deposition of calcium in the bones

#368

*!Indication for use of vitamin D is

  *++prevention and treatment of rickets

  *myasthenia gravis

  *neuralgia

  *atherosclerosis

  *violation of neuromuscular transmission

#369

*!Indication for use of acetylsalicylic acid is

  *pancreatitis

  *bronchospasm

  *atherosclerosis

  *++thrombophlebitis

  *hyperacid gastritis

#370

*!Side effect of anti-inflammatory drugs - pyrazolone derivatives is

++ violation of hematopoiesis

  *osteoporosis

  *dehydration

  *leukocytosis

  *increased blood pressure

#371

*!The mechanism of action of cromolyn sodium is

*blockade of histamine receptors

*++stabilization the membranes of mast cells

*blockade of seratonine receptors

*stabilization the membranes of leukocytes

*blockade of adrenergic receptors

#372

*!Leukopenia and agranulocytosis are most probable when using of

*L-thyroxine

*++mercazolilum

*iodine preparations

*glibenclamide

*actrapid HM

#373

*!Indication for use of glucocorticosteroids are

*++autoimmune diseases

*osteoporosis

*arterial hypertension

*lowered immunity

*myasthenia gravis

#374

*!Steroid substabce has anti-inflammatory, anti-allergic effect are poorly absorbed through the skin.

That preparation is

*prednisolone

*dexamethasone

*++flumethasone pivalate

*beclomethasone dipropionate

*triamcinolone

#375

*!Vitamin preparation providing antianemic action is

*retinol acetate

*tocopherol

*++cyanocobalamine

*ascorbic acid

*nicotinic acid

#376

*!When thiamine deficiency is developed

*pellagra

*scurvy

*++beri-beri

*xerophthalmia

*rickets

#377

*!In the absence of nicotinic acid is developed

*beriberi

*++pellagra

*pernicious anemia

*xerophthalmia

*rickets

#378

*!Vitamin preparation which improves the absorption of iron preparations from the gastrointestinal tract is

*retinol

*++ascorbic acid

*pyridoxine

*nicotinic acid

*tocopherol

#379

*!The preparation for prevention and treatment of scurvy is

*folic acid

*++ascorbic acid

*nicotinic acid

*tocopherol

*pyridoxine

#380

*!Acetylsalicylic acid inhibits enzyme

*phospholipase

*++cyclooxygenase

*lipoxygenase

*catecholamine-O-methyltransferase

*monoamine oxidase

#381

*!The preparation interferes with the interaction of histamine with the histamine receptors in tissues is

*++diphenhydramine

*prednisolone

*adrenaline

*cromolyn sodium

*ipratropium bromide

#382

*!Steroid anti-inflammatory substances are indicated in

*++collagenosis

*headache

*tooth pain

*myalgia

*neuralgia

#383

*!For prevent the release of biologically active substances used blockers of

*histamine H1 receptors

*histamine H2- receptors

*serotonine receptors

*++phospholipase A2

*beta-adrenergic receptors

#384

*!Diclofenac sodium inhibits

*phospholipase

*cyclooxygenase

*lipoxygenase

*catecholamine-o-methyltransferase

*monoamine oxidase

#385

*!The steroid compound has an anti-inflammatory, antiallergic effect, used in bronchial asthma and vasomotor rhinitis. Such a preparation is

*prednisolone

*dexamethasone

*flumethasone pivalate

*beclomethasone dipropionate

*triamcinolone

#386

*!The side effect of steroidal anti-inflammatory drugs is

*hypercholesterolemia

*osteoporosis

*bronchospasm

*hypoglycaemia

*lowering of the arterial pressure

#387

*!The mechanism of loratadine action is

  *blocks histamine receptors

  *stabilizes the membranes of mast cells

  *blocks serotonine receptors

  *stabilizes the leukocyte membranes

  *blocks adrenergic receptors

#388

*!Indication for the use of beclomethasone is

  *pancreatitis

  *bronchospasm

  *atherosclerosis

 *thrombophlebitis

  *hyperacid gastritis

#389

*!The side effect of non-steroidal anti-inflammatory drugs is

*stomach ulcer

*osteoporosis

*dehydration of the body

*hyperglycemia

*increase of arterial pressure