Eng / Enterovirus
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Immunodeficiency patients tolerate EVI severely.
Severe paralytic forms of the disease develop in HIVinfected patients and in patients with a deficiency of the humoral link of immunity. Children with X-linked agammaglobulinemia often develop chronic meningoencephalitis.
At the same time, immune T-lymphocytes can be responsible for a number of severe, destructive changes in tissues (damage to myocardiocytes in EVIS, myelin sheaths in NS damage).
Laboratory diagnostics of EVI
detection of enterovirus RNA using polymerase chain reaction (PCR) depending on the clinical form
Selected for research:
cerebrospinal fluid,
conjunctival discharge,
smear of discharged vesicles,
blood
, organ biopsy
swab (wash) from the oropharynx / nasopharynx, a swab of discharge from ulcers with herpangina,
fecal samples
autopsy material
Laboratory diagnostics of EVI
with damage to the nervous system lumbar puncture results
and studies on neuroimaging of the process (MRI, CT)
with muscle tissue damage
increased activity of "muscle" enzymes (CPK, LDH, urine myoglobin).
Diagnostics of EVI
In case of registration of an outbreak or group morbidity, the diagnosis of "enterovirus infection" can be established on the basis of clinical and epidemiological data.
Treatment
There is no etiotropic treatment for EVI.
Pathogenetic and symptomatic therapy will be carried out depending on the form and severity of the disease.
Pain and antipyretic drugs include paracetamol and ibuprofen.
Patients with pleurodynia are shown dry heat on the affected muscles. For severe pain, it may be
necessary to use non-opioid analgesics (diclofenac, ketoprofen, ketorolac, lornoxicam, etc.)
With meningitis - dehydration therapy with loop diuretics, with the development of ONGM - dexamethasone 0.25 mg / kg per day.
Treatment
Herpangina
Antiseptic solutions are locally prescribed to prevent a secondary bacterial infection, as well as drugs that relieve irritation of the mucous membrane and reduce pain.
In order to reduce swelling, antihistamines are used:
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PREVENTION
.
To exclude cases of infection of children in children's institutions
doctors, health workers, teachers, nannies, kitchen and dining room workers who have had herpangina or
who have been in contact with the patient
are suspended from work for two weeks. There is no specific prevention.
Thank you for attention!