Eng / Enterovirus
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Possible damage to the nervous system in the form of Guillain-Barré syndrome.
acute start,
severe intoxication,
increase in body temperature to febrile numbers,
rapid development of muscle paralysis, mainly of the lower extremities, neck,
intercostal.
Breathing, swallowing and speech are quickly disturbed.
Death in some cases occurs on the 2-4th day from the onset of the disease.
Enteroviral fever ("minor illness", three-day fever, summer flu)
The beginning is sharp
moderate intoxication
body temperature rises to 38.5-40 ° C and often has a twophase character.
Abdominal pain, myalgia, conjunctivitis, enlarged cervical lymph nodes are possible.
Sometimes fever is the only symptom of the disease.
Catarrhal symptoms with no pronounced respiratory manifestations.
The duration of the disease is often 3-4 days.
More common in summer
Respiratory form (catarrhal).
In the inter-epidemic period for influenza, this form of EVI accounts for 2.5 to 11% of respiratory diseases
The beginning is acute
the syndrome of intoxication is characteristic (weakness, headache, malaise), chills are possible against the background of an increase in body temperature.
Catarrhal syndrome is manifested by rhinitis with serous-mucous discharge, dry cough, hyperemia and graininess of the posterior pharyngeal wall.
Quite rarely, bronchi and lung tissue are involved in the process.
The fever persists for 3-5 days, catarrhal phenomena - about a week.
Young children may develop laryngeal stenosis caused by the ECHO11 virus.
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Enteroviral infections of the heart (EVIS).
myocarditis
encephalomyocarditis of newborns is
an extremely severe variant of Coxsackie B infection (serotypes 1–5). Ways of transmission
- transplacental and contact-household.
The onset of the disease is acute or gradual, the body temperature rises to febrile numbers and may have a two-wave character.
Cardiac syndrome is pronounced: general cyanosis of the skin, acrocyanosis progresses, the borders of the heart expand, deafness of heart tones appears, systolic murmur occurs, edema is possible.
Could be liver enlargement
Enteroviral infections of the heart (EVIS).
Damage to the central nervous system is observed:
the child refuses to breastfeed
becomes lethargic, drowsy, does not respond to people around him
tonic-clonic seizures occur.
Death can occur in the first hours from the onset of the disease or on the 2-3rd day from cardiovascular insufficiency. and, a large fontanel bulges.
Perhaps the development of coma.
Enteroviral eye damage (uveitis, hemorrhagic conjunctivitis, Apollo 11 disease
short incubation period - 3-48 hours.
The disease begins acutely. Manifestations of intoxication are expressed: fever up to 38-39°C, anxiety, sleep inversion, loss of appetite
Often there is a catarrhal syndrome.
Perhaps an increase in lymph nodes and liver, the appearance of exanthema.
On the 3rd-4th day, inflammation of the vascular tract of the eyes develops with an injection of the eyeball, serous or sero-fibrinous effusion into the anterior chamber, pupillary area or retina.
Enteroviral eye damage (uveitis, hemorrhagic conjunctivitis, Apollo 11 disease
On examination:
severe photophobia,
lacrimation, sensation of a foreign body in the eye
edematous eyelids
mucous and mucopurulent discharge.
The conjunctiva is sharply hyperemic, infiltrated, small follicles are often visible.
Enteroviral eye damage (uveitis, hemorrhagic conjunctivitis, Apollo 11 disease
The color of the iris becomes darker than on the healthy side, the pupil narrows. Almost always both eyes are affected (77.2-90.8% with an interval of 4-24 hours).
The infection resolves within 10 days without complications. In severe cases, keratitis may persist for several weeks, but usually does not lead to permanent changes.
Outbreaks of this disease, caused by enterovirus 70 and Coxsackie A24, occur mainly in tropical coastal countries.
Congenital forms of Coxsackie and ESNO infection
symptoms of severe myocarditis and (or) fulminant hepatitis, often in combination with encephalitis.
Infants between the ages of 1 week and 3 months may develop a syndrome that is difficult to distinguish from a severe bacterial infection with multiple organ failure ("viral sepsis").
The most commonly isolated viruses in these children are Coxsackie B, ECHO 11 and serotype 3 parechoviruses (PeV 3).
The role of enteroviruses in the occurrence of
kidney pathology
the development of appendicitis
hepatitis
cholecystitis
pancreatitis
endocarditis
juvenile rheumatoid arthritis has been proven.
There is an association of EVI with the development of diabetes, Reye's syndromes and chronic fatigue