Eng / Cholera_2023

Principles of therapy

In case of III-IV degree dehydration, primary rehydration is carried out by infusion of saline solutions through 2-3 catheterized veins, first by jet, then by drip

Under the control of the CVP

Temperature of injected solutions 38oC

Primary rehydration lasts 1-2 hours. During this time, existing fluid losses should be replenished.

The effectiveness of therapy will be evidenced by the normalization of blood pressure, pulse, respiratory rate, restoration of diuresis

Etiotropic therapy (tetracycline, doxycycline) is prescribed simultaneously with rehydration and is of secondary importance

Specific prophylaxis

Vaccination according to epidemic indications

Use dry or liquid cholerogen-anatoxin, contains a suspension of killed vibrio cholerae.

There are oral and parenteral vaccines

The protective effect is reduced by almost 50% after two years.

The World Health Organization recommends oral administration of two or three doses of the vaccine in 7- 10 days interval.

Persons entering countries that are unfavorable for cholera are subject to vaccination.

The introduction of cholera monovaccine is carried out 6 days before the planned date of entry.