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Английский язык / Английский язык для медиков / Толковый англо-русский и русско-английский словарь физиологических терминов Dictionary of physiology (2010)

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histidine

hiccup — икота. Sudden involuntary contraction of the diaphragm and closing the vocal folds followed by sudden stoppage of breathing characteristic sound. Repeated hiccup may result from indigestion or serious diseases e.g. alcoholism.

hidrotic — потогонный. Producing perspiration.

hindbrain — ромбовидный мозг. Part of the brain developing

 

from the posterior cerebral vesicle; it includes pons, cerebellum

 

and diencephalon.

 

hindgut — задняя кишка. Posterior part of an embryo’s intes-

 

tine from which part of the colon, rectum, urinary bladder, ureters

 

and urethra develop.

H

hippocampus — гиппокамп. One of the main structures of

the limbic system located in the depth of temporal brain lobes. It

 

forms a set of repeated, interacted micronets or modules allowing

 

the information to circulate in the given structure while training.

 

i.e. the hippocampus has a direct link with memory. It is involved

 

in orientation reflex, alarm reaction and keen attention. It emo-

 

tionally controls fear, aggression, hunger, thirst.

 

hirudine — гирудин. Anticoagulant extracted from salivary

 

glands of leeches

 

histamine — гистамин. An amine occurring as a decomposi-

 

tion product of histidine and prepared synthetically. It can be

 

found practically in all tissues of the organism — in basophilic

 

leukocytes and mast cells. Histamine possesses marked biological

 

activity making blood vessels (arterioles and venules) dilate lo-

 

cally, increasing permeability of endothelium (that result in oede-

 

ma); causing contraction of the smooth muscles e.g. in the bron-

 

chi. It’s very important inflammatory mediator released in great

 

amounts after any skin damage (with characteristic reaction —

 

reddening, swelling, pain), in case of bacterial infection etc. His-

 

tamine is also released in case of allergic reactions e.g. in bron-

 

chial asthma contributing to their further developing. Histamine

 

is an antagonist of heparin. It is a hormone of GI tract, that stim-

 

ulates secretion of hydrochloric acid by the stomach, pancreatic

 

juice, peristalsis of the stomach and intestines. See also scheme1

 

(color inset).

 

histidine — гистидин. An aminoacid resulting from the hydroly-

 

sis of many proteins. By elemination of a molecule of carbon di-

 

oxide. It is converted into histamine.

 

371

histiocyte

histiocyte — гистиоцит. Fixed macrophage of the loose connective tissue.

histology — гистология. Science about minute structure and function of tissues studied by means of special methods of staining and methods of light and electron microscopy. Syn. microscopic anatomy.

hives — крапивница. Itching rash, the result of r histamine release from the mast cells. In this case oedema develops very quickly (during several hours). Syn. urticaria.

holocrine, holocrinous — голокриновый. Pertaining to any gland or type of secretion in which the cells of the gland are fully

Hdestroyed and their protoplasm joins the secretion. See also holocrine gland.

homeostasis — гомеостаз. The ability or tendency of an organism or cell to maintain internal equilibrium by adjusting its physiological processes such as blood pressure, body temperature, ac- id-base balance etc., despite changing surroundings.

homoiothermic — гомойотермный. Capable of maintaining constant body temperature irrespective of the changes in the temperature of the surroundings. Mammals (including man) and birds are homoiotermic. Compare to poikilothermic.

hormone — гормон. A substance, secreted by endocrine glands e.g. adrenal glands, hypophisis etc. and endocrine cells, that comes into the bloodstream and is transported to different organs and tissues, where it can change their structure and influence their functions. In accordance with their chemical structure hormones can be divided into proteins and peptides, derivatives from aminoacids and steroids, — hormonal, adj.

 

 

 

Table 5

 

Classification of hormones

 

 

 

 

Group

Mechanism

Particularities

Examples

 

of action

 

 

proteins

receptor-

quick response

hormones of hypophysis,

and

mediated

(activation

hypothalamus, stomach, in-

peptides

action

of existing

testines, pancreas; calcitonin,

 

 

proteins)

parathormone

 

 

 

 

derivatives

 

 

adrenaline (derivative from

from

 

 

tryptophan)

aminoacids

 

 

 

372

 

 

 

histiocyte

 

 

 

 

Group

Mechanism

Particularities

Examples

 

of action

 

 

 

direct

slow response

thyroxine, triiodothyronin

 

action

(synthesis of

(derivatives from tyrosine)

 

 

new proteins)

 

steroid hor-

 

corticosteroids, sexual hor-

mones

 

 

mones

 

 

 

 

adrenocorticotropic hormone (ACTH) — адренокортикотропный гормон (АКТГ). A hormone, secreted by the anterior lobe of the hypophisis in response to any stress situation. ACTH controls the secretion of corticosteroids produced by the adrenal glands.

antidiuretic hormone (ADH) — антидиуретический H

гормон. See vasopressin.

follicle-stimulating hormone (FSH) — фолликулостимулирующий гормон (ФСГ). A hormone, secreted by the anterior lobe of the hypophisis. FSH stimulates growth and maturation of the ovarian follicles, secretion of estrogens and ovulation in females; in males FSH stimulates spermatogenesis in the testes.

gonadotropic hormones — гонадотропные гормоны.

Hormones synthesized and secreted by the hypophysis; gonadotropic hormones stimulate testes or ovaries (gonads), promoting synthesis of the sex hormones and spermatozoa or ovules (see ovulum, ovum) in the human organism. Synthesis of gonadotropic hormones is controlled by gonadotropic releasing hormone (gonadoliberin) of hypothalamus. The main gonadotropic hormones are follicle-stimulating hormone and luteinizing hormone. Syn. gonadotropin.

lactotropic hormone (LTH) — лактотропный гормон (ЛТГ). See prolactin.

lipotropic hormone — липотропный гормон. A hormone, secreted by the anterior lobe of the hypophysis that stimulates mobilization of fatty acids from the adipose tissue. Syn. lipotropin.

luteinizing hormone (LH) — лютеинизирующий гормон (ЛГ). A hormone, secreted by the anterior lobe of the hypophisis. LH stimulates ovulation, formation of the corpus luteum, synthesis of progesterone by ovaries in women; and synthesis of androgen by interstitial cells of testes in males.

373

histiocyte

melanocyte-stimulating hormone (MSH) — меланоцитстимулирующий гормон. A hormone, secreted by the anterior lobe of the hypophisis. In males MSH stimulates synthesis of melanin and determines location of its granules, influencing pigmentation of the skin.

natriuretic hormone — натрийуретический гормон.

A hormone, secreted by walls of the atria in response to their stretching. It relaxes smooth muscles of small blood vessels, stimulates diuresis and excretion of sodium by the kidneys, thus reducing the volume of circulating blood. This hormone also inhibits secretion of renin, activity of angiotensin II and al-

Hdosterone, lowers blood pressure.

parathyroid hormone — паратиреоидный гормон, паратгормон, паратирин. A hormone, secreted by the parathyroid glands; it regulates (together with calcitonin) level of calcium and phosphorus in the organism. In the bone tissue it activates osteoclasts that results in deminiralization of the bone tissue and increase in amount of calcium in the blood. In kidneys it stimulates reabsorbtion of calcium. Excessive amount of parathyroid hormone in the organism results in osteoporosis; parathyroid hormone deficiency results in reduction of the amount of calcium in the blood that causes increase of neuromuscular excitability, that manifests as twitches of single muscles followed by spastic contractions of muscular groups. Animal dies of tetanic cramps.

releasing hormones — рилизинг факторы, рилизинг гормоны. See hypophisis.

somatomammatropic hormone — соматомамматропный гормон, соматомамматропин. Peptide hormone, similar to somatotropic hormone in its biological characteristics, under normal conditions it is produced by placenta and in pathology by some tumors.

somatotropic hormone (STH) — соматотропин, соматотропный гормон (СТГ). A hormone, secreted by the anterior lobe of the hypophisis; stimulates growth of long bones of extremities, synthesis of proteins. Its synthesis and secretion are controlled by releasing hormone (liberin), produced by hypothalamus, and somatostatin. Hypersecretion of somatotropic hormone results in gigantism in children and

374

hypermetropia

acromegaly in adults. Hyposecretion of this hormone results in dwarfism.

thyroid-stimulating hormone (TSH) — тиреотропный гормон (ТТГ), тиреотропин. A hormone, secreted by the anterior lobe of the hypophisis. This hormone stimulates activ-

ity of the thyroid gland.

 

humoral — гуморальный. Pertaining to tissue fluid or any fluid

 

of the organism.

 

hunger — голод. A sensation of emptiness of the stomach with a

 

louging for food.

 

hydrocarbon — углеводород. A compound consisting of carbon

H

and hydrogen.

hydrocortisone — гидрокортизон. Steroid hormone one of the

 

main glucocorticoids (see corticosteroid).

 

hydrogen — водород. Chemical element of the first group of the

 

periodical system, symbol H, gas (H2), ordinal number: 1, atomic

 

mass 1,0079.

 

hydrolysis — гидролиз. The splitting of a large molecule into

 

a number of small molecules through the addition of 1 or more

 

molecules of water.

 

hydroxide — гидроксид. A compound formed by the union of a

 

metal, or of an inorganic or organic radical with one or more hy-

 

droxyl (–OH) groups.

 

hypercapnia, hypercarbia — гиперкапния. Excessive amount

 

of carbon dioxide in the blood causing overactivity in the respira-

 

tory center.

 

hyperchlorhydria — гиперхлоргидрия. Excessive secretion of

 

hydrochloric acid in the stomach that usually takes place in gas-

 

tric or duodenal ulcer.

 

hyperemia — гиперемия. Excessive amount of blood in the

 

blood vessels supplying any part of the body.

 

hyperfunction — гиперфункция. Elevated or excessive func-

 

tional activity.

 

hyperglycemia — гипергликемия. An excessive amount of glu-

 

cose in the blood. May develop in different diseases, mostly in di-

 

abetes mellitus and insufficiency of insulin in the organism and ex-

 

cessive intake of carbohydrates.

 

hypermetropia — гиперметропия, дальнозоркость. The

 

condition of the refractive media of the eye in which, with sus-

 

375

 

hyperoxia

 

pended accomodation, the focus of the parallel of light is behind

 

the retina. It is due to an abnormally short anteroposterior diam-

 

eter of the eye or to a subnormal refractive power of the media.

 

Syn. hyperopia, longsightedness. Compare to myopia. See also

 

refraction, focal distance.

 

hyperoxia — гипероксия. 1. Excess of oxygen in organs and tis-

 

sues. 2. Significant partial pressure of oxygen in the blood e.g. in

 

breathing pure oxygen.

 

hyperpnea — гиперпноэ. Deeper and frequent respiration, pro-

 

portional to increasing level of metabolism in the organism e.g.

H

hyperpnea occurs during physical exercises.

hypersensitivity — гиперчувствительность. Excessive or inad-

 

equate inflammatory immune reactions developing in reexposure

 

to a specific type of antigen (allergen). There are two forms of hy-

 

persensitivity: immediate (type I, II, III) and delayed (type IV).

type I hypersensitivity (anaphylactic) — реакция гиперчувствительности I типа (анафилактическая). An allergic reaction provoked by reexposure to a specific type of antigen. In response plasmacytes secrete antibodies — IgE. IgE bind to Fc receptors on the surface of mast cells and basophilic leukocytes that become «sensitized.» Later exposure to the same allergen, cross-links the bound IgE on sensitized cells resulting in degranulation and the secretion of pharmacologically active mediators such as histamine, leukotriene, and prostaglandin that act on the surrounding tissues. The principal effects of these products are vasodilation and smooth-muscle contraction.

type II hypersensitivity (antibody-dependent) — реакция гиперчувствительности II типа (антителозависимая). An allergic reaction in course of which the antibodies produced by the immune response bind to antigens on the patient’s own cell surfaces that results in inflammatory reactions. The antigens may either be intrinsic («self» antigen, innately part of the patient’s cells) or extrinsic (absorbed onto the cells during exposure to some foreign antigen, possibly as part of infection with a pathogen).

type III hypersensitivity (immune complex) — реакция гиперчувствительности III типа (иммунокомплекс-

376

hypofunction

ная). Allergic reactions that occur when antigens and antibodies are present in roughly equal amounts, causing extensive cross-linking. Large immune complexes are deposited in vessel walls and induce an inflammatory response.

type IV hypersensitivity (cell-mediated or Delayed-Type Hypersensitivity, DTH) — реакция гиперчувствительности IV типа (клеточно-опосредованная или ги-

перчувствительность замедленного типа, ГЗТ). A type of cell-mediated response composed of several steps: ex-

posure to an antigen that results in accumulaton of T-help-

 

ers (see lymphocyte); in reexposure macrophages recognizes the

H

antigen and act as antigen presenting cells; T-helpers interacts

with antigens on the surface of macrophages and secrete differ-

 

ent proinflammatory cytokines, thus activating T-killers and

 

mediating the immune response.

 

hypertension — гипертензия. Elevated blood pressure (over

 

140/80 mm Hg).

 

hypertonic — гипертонический. Referring to a solution whose

 

osmotic pressure is greater than that of physiologic salt solution,

 

or any other solution taken as a standart.

 

hypertrophy — гипертрофия. Enlargement of any tissue or or-

 

gan due to enlargement or multiplication of its constituent cells

 

e.g. muscles change in this way in response to high physical ex-

 

ertion.

 

hyperventilation — гипервентиляция. An abnormally in-

 

creased rate of respiration in rest leading to low carbon dioxide

 

concentration in the arterial blood.

 

hypervitaminosis — гипервитаминоз. A condition due to ex-

 

cessive intake of vitamins. It is of no danger if a man takes exces-

 

sive amount of water-soluble vitamins that are easily discharged

 

from the organism with the urine. However excessive amount of

 

fat-soluble vitamins A and D is toxic.

 

hypervolemia — гиперволемия. An abnormal increase in the

 

blood volume.

 

hypocapnia, hypocarbia — гипокапния. An abnormally low

 

carbon dioxide concentration in the blood.

 

hypofunction — гипофункция. Decreased, low or insufficient

 

functional activity.

 

377

hypoglycemia

hypoglycemia — гипогликемия. Decreased concentration of glucose in the blood; it can lead to the development of muscular weakness and dyscoordinated movements, confused consciousness and hyperhydrosis.

hypophiseal — гипофизарный. Pertaining to hypophisis.

hypophiseal-portal system — гипофизарная портальная система. The system of vessels going from the hypothalamus to the anterior lobe of hypophysis. The system takes part in transporting adenohypophysotropic hormones (liberins and statins).

hypophisis — гипофиз. One of the main endocrine glands in the

Hhuman organism; pisiform structure, located in the hypophiseal fossa in the Turkish saddle in the sphenoidal bone. The cells of the anterior lobe of the hypophisis (adenohypophysis) synthesize tropic hormones: thyroid-stimulating hormone, adrenocorticotropic hormone (see vasopressin), gonadotropic hormones (gonadotropins), somatotropic hormone (somatotropin, growth hormone), prolactin (lactotropic hormone), luteinizing hormone, lipotropiс hormone (lipotropin) and melanocyte-stimulating hormone. The secretion of these hormones is regulated by specific releasing hormones (factors): liberins — stimulators of synthesis and secretion of hormones of the adenohypophisis, and inhibitory hormones called statins; releasing hormones are produced by the hypothalamus and transported into the adenohypophysis via hypophyseal

portal system. Hypothalamic hormones oxytocin and vasopressin are secreted by supraoptic and paraventricular nuclei, then these hormones are transported in the posterior lobe of the hypophysis (neurohypophysis) and stored there. From the neurohypophysis they are secreted into the blood, — hypophyseal, adj. Syn. the pituitary.

hypophysectomy — гипофизэктомия. Surgical extraction or destruction of the hypophysis.

hypopnea — гипопноэ. Respiration less deep or/and slower than normal respiration.

hypotension — гипотензия. A condition in which the arterial blood pressure is an abnormally low. Hypotension may be due to significant fluid loss e.g. in diarrhea, massive burns or vomiting or significant blood loss.

378

immunity hypotensive — гипотензивное средство. A medication that

lowers blood pressure; used in treating hypertension.

 

hypothalamus — гипоталамус. Structure of the diencephalon,

 

located in the basis of the third ventricle. Hypothalamus contains

 

more than 30 nuclei, regulating temperature of the body, thirst,

 

hunger, water balance of the organism and its sex function. In ad-

 

dition, it’s closely linked to the emotional activity and sleep, in-

 

tegrates hormonal and vegetative nervous activities, controlls the

 

secretion of the hypophiseal hormones. See also hypophisis, hypo-

 

phiseal portal system, nuclei supraoptic, nuclei paraventricular.

 

hypotonic — гипотонический. 1. Referring to a solution with

 

less osmotic pressure than the other solution. 2. Below the normal

 

strength or tension.

I

hypotrophy — гипотрофия. General decrease in the volume of

 

a whole organ or its part.

 

hypoventilation — гиповентиляция. An abnormally shallow

 

and slow respiration that results in dramatic increase in carbon

 

dioxide concentration.

 

hypovitaminosis — гиповитаминоз. Insufficient content of

 

one or several vitamins in the organism due to their deficiency in

 

food or intolerance of the organism to them.

 

hypovolemia — гиповолемия. A decrease in the blood volume.

 

hypoxia — гипоксия. Insufficient concentration of oxygen in

 

body tissues.

 

I

icterus — желтуха. See jaundice.

ideation — процесс мышления, образование идей. The formation of a mental conception; the cerebral action by which or in accord with which, an idea is formed.

ileum — подвздошная кишка. Distal part of the small intestine. Ileum goes from the jejunum to the ileocaecal valve, — ileal, adj. imbalance — дисбаланс. Lack of balance between antagonis-

tic forces.

immunity — иммунитет. The way of protecting the organism from living bodies and substances with genetically foreign information, — immune, adj.

379

immunoglobulin (Ig)

acquired immunity — приобретенный иммунитет.

A resistance due to the interaction between the organism and pathogenic agent. It can be active or passive.

active immunity — активный иммунитет. The type of immunity in which the cells of the organism are capable of resisting developing infection or small amount of pathogenic injected into the organism by means of cell-mediated or humoral immunity.

cell-mediated immunity клеточно-опосредованный иммунитет. The type of immunity mediated by the cells (T- lymphocytes, macrophages etc.).

genetic immunity — генетический иммунитет. Resis-

Itance of any species to a certain antigen.

humoral immunity — гуморальный иммунитет. The type of immunity mediated by antibodies.

infection immunity — инфекционный иммунитет. The immune resistance to the second (repeated) infection, mediated by the proper antigen in the organism.

natural immunity — естественный иммунитет. The resistance of the species that had not been immunizated by the infection or vaccination; it is specific antigens.

passive immunity — пассивный иммунитет. The type of immunity that develops due to the injection of antibodies contained in the immune serum taken from immunized man or animal. The infants have passive immunity to some common diseases due to small amount of antibodies acquired in utero by the placental transfer from the mother or bee stings.

immunoglobulin (Ig) — иммуноглобулин. One of the blood proteins (γ-globulin) functioning as the antibodies. Ig can also be the receptor of lymphocytes. There are several types of Ig. They are IgA, IgD, IgE, IgG, IgM.

impairment — нарушение, ухудшение. Weakness or dysfunction e.g. due to any disease.

impatent — скрытый (rare use). Latent, potential, concealed, not manifest.

impermeable — непроницаемый, непроходимый. Not permiting a passage.

impulse — импульс. 1. A sudden action of any force. 2. The action potential of the nerve fiber

380