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KaK H JJ.pyrne JiaTeHTllbIC m1pyc1,1, n11pyc 9n111TeH1ia - 5app HMCCT CJ10»rnym rCI-ICTil'ICCKYIO CTpy1nypy, BKJI!OlJ3l01IJ,yrD MHOlKCCTBCHHblC peryJHITOj)HhlC rem,!. B 5I)lj)8X 3apa1KeHHblX KJICTOK o6Irnpy»,eno CTperyJ1wropm,1x 6eJIKOl.l (EBNA pOaIH KOTOpbIC H36HpaTCJibllO 3KCIT))CCCIIJ)YIOTC5f B KJICTK3X pa3HOro rrpm1cxo:,i,JI,e111rn; JJlllllb reH EBNA-1 3KcnpeccnpyeTcH HC3a­ BHC!!MO OT cpemn1ma KJICTKH·X03Hima. EBNA-2 n1,131,rnaeT aK­ nma1 HJO B-KJieTOK rryTeM CTHMyJrn1uru npoJJ.yKIUIII cpaKTopa pocTa H .3KCTIJ)CCCIIII COOTBCTCTBYIOIUCro K.:JCTO'lf!OI'O flCllCIITOpa [Sugden B., 1989]. B pesyJibTclTC llj)OIICXO)J,l!T IIJ)OJIJ](f)Cpaiurn 3apaMCHHb!X 3KTJIBHpOB3HIILIX B-KJICTOK, KOTOJ)blC BCKOpe CTa­ IIOBHTCH MHI11Cll5IMH /lc15l llHTOTOKCJillCCKHX !(JICTOK. 0)UI3KO, rrpn 3apa:,iceHHII B-KJICTOK BHpyco:1;1 BCTyflaIOT B /1,CiiC.TB!le Me­ XaHH3Mbl, 06ycJIOB,Jl!1Ba1011u1e j)C3HCTCIITHOCTI> KJICTOK K JlllTO­ TOKCH'IeCKHM K.TICTKclM. HIOKJleTirn, 3apa}ICCHHb!C rrnpycoM

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al., 1989]. B JIHMrpouHTax, Cb!B0J)0TKe Kp0BH II Cf!HHH0· M03fOBOEi }Kl!/l,K0CTH C II0M0!Ub!0 MOJICKYJIHpHoii r116pH,ll,l!33L1HH 6wrn o6ttapy)KeHbl reHCTJ1tICCKlle II0CJICJl.0BaTeJibH0CTH BHpyca rprnma. B Ka l lCCTBC [1H)ll10ilKTillllll,J., :mu;wn 6hIJIII HCII0.flb30!laHbl K,Jiom1poBaHHbIC B 11.naaMH/1,ax reHbI NP, M, Hl II H3.

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