Drugs and Pregnancy ob56-ob57.

Drugs and Pregnancy.

***) The following drugs are not given in pregnancy, except:

Tetracycline

Thiazides

Chloramphenicol

Heparin

Warfarin

Answer: D* Heparin

***) These drugs cross the placenta to the fetus, except:

Heparin

Warfarin

Tetracycline

Diazepam

Aspirin

Answer: A* Heparin

***) All of the following drugs are teratogenic, except:

Tetracycline

Paracetamol

Thiazides

Stilbestrol

Warfarin

Answer: B* Paracetamol

***) All of the following drugs are contraindicated in pregnancy, except:

Tetracycline

Iodides

Diphenylhydantoin (Epanutin)

Warfarin

Pyridoxine

Answer: E* Pyridoxine

***) One of the following drugs can be safe if used during pregnancy:

Warfarin

Septrin

Tetracycline

Erythromycin

Chloramphenicol

Answer: D* Erythromycin

***) Which of the following drugs given during pregnancy can give "Grey Baby Syndrome":

Ampicillin

Chloramphenicol

Gentamycin

Tetracycline

Streptomycin

Answer: B* Chloramphenicol

***) Regarding drugs in pregnancy, all the following are true except:

Digitalis does not cross the placenta

Warfarin crosses the placenta

Heparin does not cross the placenta

Hydralazine causes relaxing vascular smooth muscle

Methotrexate crosses the placenta

Answer: A* Digitalis does not cross the placenta

***) Brown discoloration of the teeth can occur in infants exposed in uterus to:

Penicillin

Tetracycline

Chloramphenicol

Gentamycin

Streptomycin

Answer: B* Tetracycline

Breastfeeding and Drugs.

***) Milk ejection reflex is affected by one of the following hormones:

Estrogens

Progesterone

Human placental lactogen

Oxytocin

Chorionic gonadotropin

Answer: D* Oxytocin

***) All of the following drugs are contraindicated during breast feeding except one:

Cytotoxic drugs

Chloramphenicol

Iodine

Heparin

Thiouracil

Answer: D* Heparin

***) All of the following drugs are contraindicated during breast feeding except one:

Bromocriptine

Cephalosporins

Ergotamine

Cimetidine

Tetracycline

Answer: B* Cephalosporins

Oxytocin.

***) All of the following are true regarding oxytocin, except:

Prolonged treatment can cause water intoxication

Can cause milk ejection

Single rapid IV injection can cause transient hypotension, tachycardia and ECG changes

It is not effective when given orally

It can cause contraction of the lower uterine segments

Answer: E* It can cause contraction of the lower uterine segments

***) Regarding oxytocin, one of the following is true:

Induces vigorous sustained uterine contractions

Comes from the anterior pituitary gland

Possesses no antidiuretic activity

Has long half life

Acts on myoepithelial cells of the mammary glands

Answer: E* Acts on myoepithelial cells of the mammary glands

***) All of the following are complications of Syntocinon (oxytocin) toxicity, except:

Headache

Nausea and vomiting

Polyuria

Coma

Weight gain

Answer: C* Polyuria