3. Rheumatoid Arthritis.

***) All of the following about rheumatoid arthritis are true, except:

1. More common in females

2. Splenomegaly is a feature

3. Colchicine is used in the treatment

4. Pericardial effusion may occur

5. Amyloidosis is a recognized complication

Answer: C* Colchicine is used in the treatment

***) All of the following are true about rheumatoid arthritis, except:

1. Episcleritis may occur

2. Amyloidosis is a recognized complication

3. Causes carpal tunnel syndrome

4. Pericarditis may occur

5. Retinitis pigmentosa is a feature

Answer: E* Retinitis pigmentosa is a feature

***) All of the following are manifestations of rheumatoid arthritis except:

1. Pleural effusion

2. Firm, non tender nodules

3. Pitting of nails

4. Scleritis

5. Pericarditis

Answer: C* Pitting of nails

***) All of the following joints may be involved in rheumatoid arthritis, except:

1. Proximal interphalangeal joints

2. Knee joints

3. Distal interphalangeal joints

4. Wrist joints

5. Ankle joints

Answer: C* Distal interphalangeal joints

***) All of the following are extra-articular manifestations of rheumatoid arthritis, except:

1. Pericarditis

2. Mononeuritis multiplex

3. Fibrosing alveolitis

4. Pneumoconiosis

5. Scleritis

Answer: D* Pneumoconiosis

***) All of the following are extra-articular manifestations of rheumatoid arthritis, except:

1. Pleural effusion

2. Episcleritis

3. Keratoderma blenorrhagica

4. Anemia

5. Keratoconjunctivitis sicca

Answer: C* Keratoderma blenorrhagica

***) All of the following are seronegative arthritis, except:

1. Ankylosing spondylitis

2. Psoriatic arthritis

3. Reiter's syndrome

4. Rheumatoid arthritis

5. Reactive arthritis

Answer: D* Rheumatoid arthritis

***) Rheumatoid arthritis may cause all of the following in the hand, except:

1. Joint ankylosis

2. Rupture of extensor tendons

3. Intrinsic contractures

4. Rupture of flexor tendons

5. Heberden's nodes

Answer: E* Heberden's nodes

***) Which of the following is not a feature of Felty's syndrome:

1. Lymphadenopathy

2. Splenomegaly

3. Polycythemia

4. Rheumatoid arthritis

5. Leucopenia

Answer: C* Polycythemia

3. Crystal Arthropathies.

1. Gout.

***) Acute attacks of gout rarely affect the:

1. First metatarsophalangeal joint

2. Shoulder

3. Ankle

4. Wrist

5. Elbow

Answer: B* Shoulder

***) A 50 years old male awoke in the midnight with severe pain in his left big toe. He was taking some diuretics for hypertension. His toe was swollen, hot and severely tender, and patient was unable to stand on it. The most probable diagnosis is:

1. Reiter's syndrome

2. Acute pyogenic arthritis

3. Rheumatoid arthritis

4. Osteoarthritis

5. Acute gouty arthritis

Answer: E* Acute gouty arthritis

***) Acute gouty arthritis can be precipitated by all of the following, except:

1. Initiation of all purina therapy

2. Alcohol

3. Severe dieting

4. Steroid therapy

5. Surgery

Answer: D* Steroid therapy

***) In gouty arthritis which of the following is the most specific diagnostic finding:

1. Family history of gout

2. Presence of sodium urate crystals in synovial fluid

3. Prompt response to colchicine therapy

4. Presence of hyperuricemia

5. Involvement of the big toe

Answer: B* Presence of sodium urate crystals in synovial fluid

***) Each of the following is acceptable for treatment of acute gouty arthritis, except:

1. Indomethacin

2. Oral colchicine

3. Azapropazone

4. Allopurinol

5. ACTH IM

Answer: D* Allopurinol

***) Which drug inhibits uric acid synthesis by inhibiting xanthine oxidase:

1. Probenecid

2. Phenylbutazone

3. Colchicine

4. Allopurinol

5. Indomethacin

Answer: D* Allopurinol