In hypothyroidism the following type of hyperlipoproteinemia (according Fridricson e. Classification) is evident:

A. Type I

*B. Type IV

C. Type III

D. Type II

E. Type V

Periodic renal colics attacks are observed in a woman with primary hyperparathyroidizm. Ultrasonic examination revealed small stones in the kidneys. What is the most plausible reason of the stones's formation?

*A. Hypercalcemia

B. Hyperuricemia

C. Hypercholesterinemia

D. Hyperphosphatemia

E. Hyperkalemia

Choose the hormone whose secretion is suppressed at diabetes insipidus in patient:

*A. Vasopressin

B. Somatotropin

C. Thyrotropin

D. Melatonin

E. Oxytocin

A 60-year old patient with a long history of stenocardia takes coronarodilator agents. He has also been administrated acetylsalicylic acid to reduce platelet aggregation. What is the mechanism of anti-platelet action of acetylsalicylic acid?

A. It has membrane stabilizing effect

B. It reduces the activity of phosphodiesterase

C. It enhances the synthesis of prostacyclin

*D. It reduces the activity of cyclooxygenase

E. It enhances the activity of platelet adenylate cyclase

A patient has been administrated an anti-inflammatory drug that blocks the action of cyclooxygenase. Specify this anti-inflammatory agent:

A. Analgene

B. Thiamin

*C. Aspirin

D. Creatine

E. Allopurinol

Acromegaly in patient is associated with excessive synthesis of a hormone:

A. Thyrotropin

B. Melatonin

*C. Somatotropin

D. Oxytocin

E. Vasopressin

Utilization of arachidonic acid via cyclooxygenase pathway results in formation of some bioactive substances. Name them:

A. Biogenic amines

B. Insulin-like growth factors

C. T3 and T4

D. Somatomedins

*E. Prostaglandins

All increases serum glucose except:

A. Cortisol

B. Nor-epinephrine

C. Glucagon

D. Epinephrine

*E. Vasopressin

A patient who suffers from pneumonia has high body temperature. What biologically active substances play the leading part in origin of this phenomenon?

A. Interleukin

*B. Leukotrienes

C. Serotonin

D. Histamine

E. Bradykinin

A man after 1,5 liter blood loss has suddenly reduced diuresis. The increased secretion of what hormone caused this diuresis alteration?

A. Cortisol

B. Corticotrophin

*C. Vasopressin

D. Parathormone

E. Natriuretic

There is only one hormone among neurohormones which refers to the derivatives of amino acids according to classification. Point out it:

A. Oxytocin

B. Thyroliberin

C. Vasopressin

D. Somatotropin

*E. Melatonin

Hyperpigmentation is considered at patients with Addison`s disease. Propose the hormone whose high level in the blood can cause this state:

A. ACTH

*B. MSH

C. Prolactin

D. FSH

E. TSH

A patient who had been continuously taking drugs blocking the production of angiotensin II developed bradycardia and arrhythmia. A likely cause of these disorders is:

A. Hypokalemia

B. Hypernatremia

*C. Hyperkalemia

D. Hypocalcemia

E. Hypercalcemia

A middle-aged man went to a foreign country because he had been offered a job there. However he had been unemployed for quite a long time. What endocrine glands were exhausted most of all in this man?

*A. Adrenal glands

B. Parathyroid glands

C. Substernal gland

D. Seminal glands

E. Thyroid gland

Products of some proteins hydrolysis and modification are the biologically active substances called hormones. Lipotropin, corticotrophin, melanotropin and endorphins are synthesized in the hypophysis of the following protein:

*A. Proopiomelanocortin (POMC)

B. Neuroalbumin

C. Neurostromin

D. Thyroglobulin

E. Neuroglobulin

Examination of a patient revealed overgrowth of facial bones and soft tissues, tongue enlargement, wide interdental spaces in the enlarged dental arch. What changes of the hormonal secretion are the most likely?

A. Hyposecretion of thyroxine

B. Hypersecretion of insulin

*C. Hypersecretion of the somatotropic hormone

D. Hyposecretion of insulin

E. Hyposecretion of the somatotropic hormone

Which of the following compound antagonizes the actions of insulin in the liver?

A. Neuropeptide Y

B. Neuropeptide A

*C. Growth hormone

D. Substance P

E. Vasoactive intestinal peptide

Secretion of what gastrointestinal hormones will be primarily decreased as a result of duodenum removal?

A. Histamine

B. Gastrin and histamine

C. Neurotensin

D. Gastrin

*E. Cholecystokinin and secretin

A 26-year old woman at 40 weeks pregnant has been delivered to the maternity ward. Objectively: the uterine cervix is opened, but the contractions are absent. The doctor has administrated her a hormonal drug to stimulate the labor. Name this drug:

A. Testosterone

*B. Oxytocin

C. ACTH

D. Estrone

E. Hydrocortisone

For glucose entry into the cells, insulin is required in all cells except that of:

A. Renal medulla

*B. Red Blood Cells

C. Liver

D. Pancreas

E. Heart