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INTERNAL DISEASES

An Introductory Course

Edited by V.Vasilenko and A.Grebenev

Translated from the Russian by Alexander Rosinkin

Mir Publishers Moscow

PREFACE

ISBN 5-03-001686-4

First published 1987

Second edition 1990

Revised from the 1989 Russian edition

PHnted in the Union of Soviet Socialist Republics Ha am/iuiicKOM A3biKe

© H3;iaTejn>cTBo «MeimuHHa», 1989,

C H3MeHeHI}aMH

© English translation, A.Rosinkin, 1990

Internal medicine is the major branch of medical practice and research because internal diseases are the most common and run a grave and pro­tracted course involving many complications and impairing the patient's objective condition and his working capacity. Internal diseases have the highest mortality rates as well. Therefore prophylaxis of internal diseases is the main concern in the health care system of all countries, and the study of internal diseases is the leading subject of medical training.

The term "internal diseases" came into use in the 19th century to stand alongside with the then-popular term "therapy". The development of new, complicated methods of diagnosis and treatment, requiring specialized skills and training on the part of the physician, has led to the formation of separate branches of medicine such as cardiology, gastroenterology, en­docrinology, and haematology. This by no means indicates the division of the concept of "internal medicine" into "daughter subjects". Clinical medicine of the second half of this century is characterized by parallelism of differentiation and integration. Therefore, despite a further separation of special branches, general medical training and education, and the in­tegrating research into internal diseases and related subjects are now even more important.

It should also be noted that the new offshoots of medicine develop at the "interface" of several clinical subjects. Thus cardiology, which was formerly only a branch of internal medicine, gave rise to heart surgery and anaesthesiology.

At the present time the knowledge of internal diseases has improved greatly: many new diseases have been described, the aetiology and pathogenesis of the known diseases and their clinical course studied, and new methods of diagnosis and treatment have been developed and improv­ed. Therefore, despite the branching of internal medicine into special sub­jects, the amount of knowledge that is necessary today for a practitioner is much greater than say 20 or even 10 years ago. The requirements for ade­quate medical training have thus increased accordingly.

The course in internal diseases is given differently in various countries: the student may be educated at one clinic during his entire course of studies, or he may take classes in different departments consecutively. But in all cases there exists a certain optimum sequence in the studies. During their first years (usually the third year) the students study the main methods of examination, symptoms of internal diseases, and the main principles of

6 Foreword

their management. This book is a course in diagnostic principles and special pathology. In other words, this is an introduction to therapy, ox pro­paedeutics to internal diseases. This course is given to students after they have studied the fundamentals of medicine, such as anatomy, physiology, biochemistry, etc.

During their further studies the students broaden and improve their knowledge of all major internal diseases, their differential diagnoses, and their treatment. The students start managing patients independently. Future physicians are thus trained in stages.

This particular manual is intended for third-year medical students. It describes symptoms and syndromes, the main methods of examination used by internists and methodology of diagnosis. It helps students master the practical diagnosis of internal diseases and their management. The authors hope that this manual will help the student in his further detailed study of internal diseases and that it may also be useful to those who master other special medical subjects. The authors believe also that this book may be helpful to a practitioner.

The contributors to this manual are members of the staff of the Moscow First Medical Institute named after I. Sechenov.

The authors would gladly accept any criticisms or comments which would improve this manual.

Contributing Authors

Golochevskaya, V. S. Grebenev, A. L.

| Mikhailova, N. P. |

Pletneva, N. G. Sheptulin, A. A.

| Shirokova, K. I. |

| Vasilenko, V. Kh. | Yakovleva, V. S.

| Zaikin, M.D.|

Contents

GENERAL PART 11

Chapter 1. Internal Medicine: Subject Matter, Purpose and Objectives 11

General Concepts 11

Admitting Medical Students to the Clinic and Fundamentals of Medical

Deontology .. 17

Chapter 2. History of Diagnosis 23

A Short History Survey 23

The Role of Russian and Soviet Scientists in Development of Diagnosis and the

General Therapy of Internal Diseases 27

Soviet Public Health System: A New Stage in Medicine 30

Chapter. 3. Methods of Clinical Examination of Patients and General Symptoma­ tology of Diseases of the Internal Organs 32

Inquiry 33

The Present Complaints 34

History of the Present Disease 35

Anamnesis Vitae 35

Physical Examination 40

General Inspection 41

Palpation 53

Percussion 54

Auscultation 57

Laboratory and Instrumental Methods of Examination 60

Anthropometry 61

Thermometry ... 63

X-ray Study 69

Endoscopy, Biopsy, and Cytological Studies 71

Instrumental-Functional Methods of Examination 72

Radioisotope Methods 72

Ultrasound Echography 73

Laboratory Methods of Examination 76

Chapter 4. General Methodology of Diagnosis 77

The Importance of Medical Theory for Development of Diagnostics 77

Planning Diagnostic Examination 82

Special Features of Diagnostic Examination 83

Diagnostic Observation and Examination 84

Recording Form 87

Types of Diagnosis . 87

Methods and Theory of Diagnosis 87

Prognosis 99

SPECIAL PART Ill

Chapter 5. Respiratory System Ill

Methods of Examination Ill

Inquiry Ill

Physical Examination 116

Instrumental and Laboratory Methods 143

Main Clinical Syndromes 159

Special Pathology 164

Bronchitis 165

Contents

Bronchial Asthma 168

Acute Pneumonia 171

Pulmonary Abscess 178

Pleurisy 181

Chronic Pneumonia 186

Bronchiectasis 187

Emphysema of the Lungs 190

Chapter 6. Blood Circulatory System 192

Methods of Examination 192

Inquiry 192

Physical Examination 195

Physical and Instrumental Studies of the Vessels 220

Instrumental Study of the Heart 234

Major Clinical Syndromes 256

Cardiac Rhythm Disorders (Arrhythmias) 256

Circulatory Insufficiency 256

Special Pathology 257

Rheumatism 285

Bacterial (Septic) Endocarditis 290

Heart Valvular Diseases 292

Myocarditis 311

Cardiomyopathy 312

Pericarditis 314

Essential Hypertension 316

Atherosclerosis 319

Ischaemic Heart Disease 322

Angina Pectoris 322

Myocardial- Infarction 325

Cardiosclerosis 330

Chapter 7. Digestive System 332

Oesophagus 332

Methods of Examination ….. 332

Inquiry 332

Physical Examination 333

Laboratory and Instrumental Methods 334

Special Pathology 334

Achalasia of the Cardia 334

Oesophagitis 335

Stomach 337

Methods of Examination 337

Inquiry 337

Physical Examination 342

Laboratory and Instrumental Methods 345

Special Pathology 355

Gastritis 355

Peptic Ulcer Disease (Gastric and Duodenal Ulcer) 358

Intestine 364

Methods of Examination 364

Inquiry 364

Physical Examination 368

Laboratory and Instrumental Methods 378

Major Clinical Syndromes 385

The Acute Abdomen 385

Inadequate Digestion Syndrome 387

Contents 9

Malabsorption Syndrome 389

Special Pathology 390

Acute Enterocolitis 391

Chronic Enteritis 391

Chronic Colitis 392

Liver and Bile Ducts 394

Methods of Examination 394

Inquiry 394

Physical Examination 396

Laboratory and Instrumental Methods 406

Main Clinical Syndromes 430

Jaundice 430

Portal Hypertension 433

Hepatolienal Syndrome 434

Hepatic Insufficiency and Coma 435

Special Pathology 438

Chronic Hepatitis 438

Cirrhosis of the Liver 441

Cholelithiasis 447

Cholecystitis 452

Pancreas…………………………………………………………………… 456

Methods of Examination ……………………………………………………456

Inquiry 456

Physical Examination 457

Laboratory and Instrumental Methods 458

Major Clinical Syndromes 463

Exocrine Pancreatic Insufficiency 463

Special Pathology 464

Pancreatitis 464

Chapter 8. Urinary System 468

Methods of Examination 468

Inquiry 468

Physical Examination 473

Instrumental and Laboratory Methods 478

Main Clinical Syndromes 495

Renal Oedema 495

Nephrotic Syndrome 498

Renal Hypertension 500

Renal Eclampsia 503

Renal Failure 504

Special Pathology 508

Diffuse Glomerulonephritis 508

Toxic Kidney 515

Amyloidosis of the Kidney (Amyloid Kidney) 515

Nephrolithiasis 517

Pyelonephritis 520

Chapter 9. Diseases of the Blood 522

Methods of Examination 522

Inquiry 522

Physical Examination 524

Instrumental and Laboratory Methods 528

Special Pathology ..... 545

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