- •The approximate timing of classes
- •Practice work
- •Glossary
- •Office hours (2) Formation of practical skills on the theme «The subject, purposes and methods of pathological physiology”.
- •Case study
- •The approximate timing of classes
- •Practical work of students
- •Questions 1. What factors affect the mouse in this experiment?
- •2. Which of these factors could be considered the leading cause of the pathologic process - hypobaric hypoxia?
- •3. How can you experimentally check your presumptions about the nature of the pathologic process?
- •Pathogenesis of High altitude disease
- •Vicious circle in pathogenesis of High altitute disease
- •Office hours (2) Formation of practical skills on the theme «General etiology and pathogenesis. Effects of low barometric pressure on an organism”
- •Case Study Case 1. A group of tourists came under heavy rain. A day later, one of them developed pneumonia. Questions:
- •The approximate timing of classes
- •Glossary:
- •Office hours (2) Formation of practical skills on the theme «The role of reactivity of an organism in pathology”
- •The approximate timing of classes
- •Practical work of students
- •Explain the pathogenesis of hemolysis in tubes №№ 2-5 and the absence of hemolysis in tube number 1. Glossary
- •Office hours (2) Formation of practical skills on the theme “Cell injury”
- •Case Study
- •The approximate timing of classes
- •Practical work of students
- •I nfection, ischemia, traumas, tumors, burns, immune pathological processes, etc.
- •The significance of acute phase reactions for organism
- •Glossary
- •Types of fever on the basis of the extent of temperature elevation:
- •Types of fever on the basis of temperature fluctuation:
- •- Remittent (fluctuation 1-20c) (viral and bacterial infections, exudative pleuritis)
- •Control -test Office hours (2) Formation of practical skills on the theme “systemic organism’s response to damage. Fever”
- •Case Study
- •Control – conclusions on the cases
- •The approximate timing of class
- •Practical work of students
- •Glossary
- •Office hours (2) Formation of practical skills on the theme “Disorders of water and electrolyte metabolism”
- •The approximate timing of classes
- •Vasoconstriction Vasodilation of brain vessels High irritability of n. Vagus
- •Non respiratory (metabolic) alkalosis
- •Compensatory mechanisms at abb disorders
- •Glossary
- •Nongaseous acidosis (metabolic, exogenous, excretory) develops when there is accumulation of acidic products (metabolic disorders, acid intake from outside, diarrhea)
- •Office hours (2) Formation of practical skills on the theme “Acid-base disorders”
- •The approximate timing of classes
- •Practical work of students
- •Glossary
- •Control -test Office hours (2) Midterm control 1
- •The approximate timing of class
- •Practical work of students
- •Глоссарий
- •Office hours (2) Formation of practical skills on the theme “Disorders of carbohydrate metabolism”
- •The approximate timing of class
- •Case-study case 1
- •Control -test Office hours (2) Formation of practical skills on the theme “Disorders of protein and lipid metabolism”
The approximate timing of classes
№ |
Steps of the class |
Time (min) |
1 |
Organizational part. Roll Call, reading the goals and objectives of the class, distribution of demonstration material |
5 |
2 |
Discussion the questions |
45 |
3 |
Break |
10 |
4 |
Video film and discussion of results, conclusions |
30 |
5 |
Test |
10 |
6 |
Summarizing the classroom work, assessment of competencies |
10 |
Practical work of students
The task № 1. |
To value a role of species in reactivity. |
Technique: A mouse and a frog are placed into tha ballone of Komovsky’s apparatus. Pay attention to behaviour of animals, character of breath, color of skin and mucous. Gradually reducing barometric pressure, mark distinction in manifestations of high-altitude disease at animals. The received data analyze.
The task № 2. |
To find out the role of age in reactivity. |
Technique: An adult mouse (weight 18-20г.) and a newborn mouse are placed into the balloone of Komovsky’s apparatus. Pay attention to behaviour of animals, character of breath, color of skin and mucous. With the help of the pump gradually pump out air. Watch development of high-altitude illness in both animals. Conclude about the role of age in reaction of animals to low oxygen content.
The task № 3. |
To find out the role of CNS function in reactivity. |
Technique: Three adult mice are taken in experiment. Inject 1 % solution of Hexanal (0,5 ml per 100g of weight) subcutaneously to one of, 10 % solution of caffeine (0,5 ml per 100g of weight) to another. The third mouse is the control. 5-6 minutes after injections all mice are placed into the balloone of Komovsky’s apparatus. Repeat a course of the previous experiments, pay attention to a difference in behaviour of animals. Analyze the received data.
The task № 4. |
To study the role of environmental factors in reactivity of an organism. |
Technique: Take three mice. One mouse is cooled in the refrigerating chamber for 20 minutes, another is placed to thermostat at temperature of 400С for 10 minutes. The third mouse is the control. All mice are placed into the balloone of Komovsky’s apparatus. Model high-altitude illness. Pay attention to a difference in behavior of animals, conclude.
The report
Animals |
Course experience |
Behavior |
Character of breath |
Color of skin and mucous |
The form of response |
Frog |
Initial condition High-altitude illness |
|
|
|
|
The mouse № 1 (control) |
Initial condition High-altitude illness |
|
|
|
|
The mouse № 2 (newborn) |
Initial condition High-altitude illness |
|
|
|
|
The mouse № 3 (narcosis) |
Initial condition High-altitude illness |
|
|
|
|
The mouse № 4 (caffeine) |
Initial condition High-altitude illness |
|
|
|
|
The mouse № 5 (hyperthermia) |
Initial condition High-altitude illness |
|
|
|
|
The mouse № 6 (hypothermia) |
Initial condition High-altitude illness |
|
|
|
|