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METHODOLOGY TEXT BOOK 2009 2010.doc
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Infants & children:

No special problems expected.

Prolonged use:

  • You may become more susceptible to infections caused by germs not responsive to penicillins.

  • Talk to your doctor about need for follow-up medical examinations or laboratory studies.

Skin & sunlight:

No problems expected.

Driving, piloting or hazardous work:

Usually not dangerous. Most hazardous reactions likely to occur a few minutes after taking penicillin.

Discontinuing:

Don’t discontinue without doctor’s advice until you complete prescribed dose, even though symptoms diminish or disappear.

Others:

  • Urine sugar test for diabetes may show false positive result.

  • If your symptoms don’t improve within a few days (or if they worsen), call your doctor.

  • Don’t take medicines for diarrhea without your doctor’s approval.

  • Birth control pills may not be effective. Use additional birth control methods.

POSSIBLE INTERACTION WITH OTHER DRUGS

GENERIC NAME OR DRUG CLASS COMBINED EFFECT

Chloramphenicol Decreased effect of both drugs.

Cholestyramine May decrease penicillin effect.

Colestipol May decrease penicillin effect.

Contraceptives, oral Impaired contraceptive efficiency.

Erythromycins Decreased effect of both drugs.

Methotrexate Increased risk of methotrexate toxicity.

Probenicid Increased effect of all penicillins.

Sodium benzoate & sodium phenylacetate May reduce effect of sodium benzoate

& sodium phenylacetate.

Sulfonamides Decreased effect of both drugs.

Tetracyclines Decreased effect of both drugs.

POSSIBLE INTERACTION WITH OTHER SUBSTANCES

Interacts with combined effect

Alcohol: Occasional stomach irritation.

Beverages: None expected.

Cocaine: No proven problems.

Foods:

Acidic fruits or juices, aged cheese, wines, Decreased antibiotic effect.

Syrups (if taken with penicillin G).

Marijuana: No proven problems.

Tobacco: None expected.