Заключение

В курсовой работе были рассмотрены:

1. путем системного поиска выявлены оптимальные параметры и условия молекулярного докинга, позволяющие охарактеризовать комплексы тетрамеров гемоглобина с Ар₄А.

2. одним из центров связывания Ар₄А с гемоглобином в T- и R-формах гемоглобина человека является DPG-связующий регуляторный сайт.

3. молекулярное моделирование гемоглобина с Ар₄А позволило обнаружить ряд дополнительных центров связывания Ар₄А в поверхностных областях гемоглобина.

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