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Tissues СЕСТРИ ІІІ Курс.doc
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  1. Connective: contains many different cell types including: fibroblasts, macrophages, mast cells, and adipocytes. Connective Tissue Matrix is made of two materials: ground substance - proteins and polysaccharides, fiber – reticular, collagen and elastic. Classification of Connective Tissue:

    • Loose Connective - fibers & many cell types in gelatinous matrix, found in skin, & surrounding blood vessels, nerves, and organs.

    • Dense Connective - Bundles of parallel collagen fibers& fibroblasts, found in tendons& ligaments.

    • Cartilage - Cartilage is made of collagen & elastin fibers embedded in a matrix glycoprotein & cells called chondrocytes, which was found in small spaces.

    • Cartilage has three subtypes:

      • Hyaline cartilage – Weakest, most abundant type, Found at end of long bones, & structures like the ear and nose,

      • Elastic cartilage- maintains shape, branching elastic fibers distinguish it from hyaline and

      • Fibrous Cartilage - Strongest type, has dense collagen & little matrix, found in pelvis, skull & vertebral discs.

  2. Muscle: is divided into 3 categories, skeletal, cardiac and smooth.

    • Skeletal Muscle – voluntary, striated, striations perpendicular to the muscle fibers and it is mainly found attached to bones.

    • Cardiac Muscle – involuntary, striated, branched and has intercalated discs

    • Smooth Muscle – involuntary, nonstriated, spindle shaped and is found in blood vessels & the GI tract.

  3. Nervous: Consists of only two cell types in the central nervous system (CNS) & peripheral nervous system (PNS):

    • Neurons - Cells that convert stimuli into electrical impulses to the brain, and Neuroglia – supportive cells.

    • Neurons – are made up of cell body, axon and dendrites. There are 3 types of neurons:

      • Motor Neuron –  carry impulses from CNS to muscles and glands,

      • Interneuron - interpret input from sensory neurons and end responses to motor neurons

      • Sensory Neuron – receive information from environment and transmit to CNS.

    • Neuroglia – is made up of astrocytes, oligodendrocytes, ependymal cells and microglia in the CNS, and schwann cells and satellite cells in the PNS.

Development: All tissues of the body develop from the three primary germ cell layers that form the embryo:

  • Mesoderm – develops into epithelial tissue, connective tissue and muscle tissue.

  • Ectoderm - develops into nervous tissue and epithelial tissue.

  • Endoderm – develops into epithelial tissue.

Cell Junctions:

  • Tight Junctions - Form a seal between cells, define apical and basal sides of an epithelial cell

  • Gap Junctions - An open junction between two cells, which allows ions, & small molecules to pass freely between the cells.

  • Adherens Junctions - Link actin cytoskeletal elements in two cells.

  • Desmosomes - Link keratin filaments in adjoining cells and resist shearing forces.

  • Hemidesmosomes - Anchor keratin fibers in epithelial cells to the basement membrane through integrin anchors.

3.3. Рекомендована література:

Основна: Козырева Л. Г. «Английский язык для медицинских колледжей и училищ: учебное пособие / Л. Г Козырева, Т. В. Шад­ская. — Изд. 7-е. — Ростов н/Д : Феникс, 2007.

Допоміжна: С.А.Тылкина «Пособие по английскому языку » М:1985 ст.57

3.4. Орієтновна карта для самостійної роботи з літературою з даної теми:

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Questions:

1

A tissue is formed by a group of ______________ performing or associated with similar function.

A)

tissues

B)

cells

C)

organ systems

D)

macromolecules

2

There are four primary types of tissues; they are

A)

epithelial, cartilage, muscular and brain

B)

connective, epithelial, skin and blood

C)

epithelial, connective, muscular and nervous

D)

glands, bone, lungs and kidneys

3

Muscle tissue is characterized by its

A)

strength

B)

durability

C)

contractility

D)

rigidity

4

A tissue specialized for energy storage and thermal insulation is

A)

cartilaginous tissue

B)

muscular tissue

C)

adipose tissue

D)

epithelial tissue

5

Which of the following is not one of the four primary classes of tissue?

A)

cartilaginous tissue

B)

connective tissue

C)

epithelial tissue

D)

muscular tissue

6

All permanent connective tissues originate with the _______ of the embryo.

A)

ground substance

B)

adipose tissue

C)

mucous tissue

D)

mesenchyme

7

About 90% of all cancers originate from

A)

epithelium

B)

connective tissue

C)

muscle tissue

D)

nervous tissue

8

When different varieties of tissues are associated to perform a function they form the structure known as ___________.

A)

specialized tissue

B)

organ

C)

cells

D)

organ system

9

Epithelial tissue is characterized by

A)

tightly packed cells

B)

absence of any basement membrane

C)

extensive extracellular matrix

D)

a rich blood supply

10

The various types of epithelium are classified by the

A)

size and shape of cells

B)

shape of cells and number of cell layers

C)

number of cell layers and size of the cells

D)

size and location of cells

11

Epithelial tissue is distinguished from connective tissue, muscular, or nervous tissue by its

A)

large extracellular matrix

B)

contractility

C)

ability to carry action potentials

D)

basement membrane

12

Simple epithelium has one layer of cells on the basement membrane, ___________ epithelium has more than one layer of cells.

A)

squamous

B)

fibrous

C)

stratified

D)

simple

13

Which of the following cell organelles would be most important in secretory epithelial cells?

A)

cilia

B)

Golgi apparatus

C)

lysosomes

D)

desmosomes

14

Lining of blood capillaries supplying body cells with oxygen and nutrients, are expected to consist of

A)

connective tissue

B)

simple squamous epithelium

C)

stratified squamous epithelium

D)

simple columnar epithelium

15

Epithelial tissue that can stretch or is subjected to stress would have many

A)

desmosomes

B)

gap junctions

C)

tight junctions

D)

basement junctions

16

Glands whose ducts have few branches are called

A)

simple

B)

compound

C)

acinar

D)

alveolar

17

In a(n) _______ gland, entire cells break down to form the secretion.

A)

exocrine

B)

merocrine

C)

holocrine

D)

autocrine

18

According to their function, there are two major types of epithelial tissue, these are

A)

epithelial tissue and cartilage

B)

holocrine and apocrine glands

C)

transitional and pseudostratified epithelium

D)

covering and secretory epithelium

19

Glands that produce a thick, sticky secretion are called _______ glands.

A)

serous

B)

acinar

C)

mucous

D)

compound

20

The epithelium that lines the stomach and intestines is

A)

simple cuboidal

B)

simple columnar

C)

pseudostratified

D)

transitional

21

The epithelium that lines the passages of the respiratory and reproductive system is called

A)

simple squamous epithelium

B)

stratified epithelium

C)

simple cuboidal and columnar epithelium

D)

pseudostratified columnar epithelium

22

The secretions of endocrine glands are released directly

A)

onto the skin surface

B)

into the bloodstream

C)

into a gland duct

D)

into the brain tissue

23

Which type of epithelium is best suited for rapid filtration?

A)

simple squamous

B)

stratified squamous

C)

pseudostratified

D)

stratified cuboidal

24

What is the general function of glands?

A)

protect the body

B)

control the function of epithelial tissues

C)

produce and secrete specialized compounds to control and maintain different body function

D)

help to maintain blood pressure and nerve actions

25

A carcinoma is a cancer originating from

A)

epithelium

B)

connective tissue

C)

muscle tissue

D)

nerve tissue

26

Which of the following is a function of epithelial tissue?

A)

Conduction of action potentials

B)

Secretion and absorption of molecules

C)

Support and covering of other tissue types

D)

Contraction and relaxation

27

The tissue that forms the inner lining of the respiratory passages is

A)

pseudostratified

B)

ciliated

C)

mucus-secreting

D)

All of the above.

28

Connective tissue exists in different forms (within the human body) from liquids to very hard solids of the presence of the ___________________.

A)

cartilage

B)

collagen and elastin

C)

extracellular matrix

D)

cells are surrounded by membranes

29

Connective tissue fibers are produced by

A)

macrophages

B)

mast cells

C)

fibroblasts

D)

All of the above.

30

Collagen, elastin, and reticular fibers in connective tissues are formed by

A)

phospholipids

B)

carbohydrates

C)

adipose tissue

D)

proteins

31

Extracellular liquid matrix in blood is

A)

adipose

B)

plasma

C)

fibroblast

D)

calcium salt

32

The gel of the extracellular matrix is composed mostly of water and

A)

proteoglycans

B)

collagen

C)

keratin

D)

reticular fibers

33

Macrophages almost as abundant as fibroblasts are specialized in

A)

support

B)

protection

C)

secretion

D)

phagocytosis

34

Bone cells are arranged in concentric circles around longitudinal tubes called

A)

osteons

B)

osteonic canals

C)

lacunae

D)

canaliculi

35

Extracellular matrix in bone is formed by

A)

mineral salts

B)

reticular fibers

C)

collagen and elastin

D)

lipids

36

A general characteristic of connective tissue is that it

A)

consists of cells with much intercellular material between them

B)

has no blood supply to the tissue

C)

covers the outside of organs

D)

commonly is found lining body cavities

37

Cartilage tissues are likely to be slow in healing following an injury because

A)

cartilage cells cannot reproduce

B)

they lack direct blood supplies

C)

the intercellular material is missing

D)

cartilage cells are surrounded by fluids

38

When cardiac muscle cells are damaged by a heart attack, they are usually replaced by

A)

connective tissue cells

B)

new smooth muscle cells

C)

new cardiac muscle cells

D)

epithelial cells

39

Dense regular collagenous connective tissue would be found in

A)

a nerve

B)

the brain

C)

a ligament

D)

skull bone

40

Blood cells are produced in hemopoietic tissue found in

A)

yellow bone marrow

B)

thymus

C)

red bone marrow

D)

spleen

41

The only type of cell seen in a tendon is

A)

muscle fibers

B)

reticular cells

C)

collagenous cells

D)

fibroblasts

42

The shape of a person's ear is due mainly to

A)

dense regular connective tissue

B)

dense irregular connective tissue

C)

elastic cartilage

D)

fibrocartilage

43

Which of these is NOT a connective tissue?

A)

blood

B)

muscle

C)

cartilage

D)

areolar tissue

44

Tendons and ligaments contain the protein

A)

keratin

B)

fibrin

C)

lignin

D)

collagen

45

The secretory cells of a gland are supported by a connective tissue framework called the

A)

serosa

B)

stroma

C)

parenchyma

D)

trabecula

46

The perichondrium is a layer of fibroconnective tissue surrounding

A)

a bone

B)

most cartilage

C)

a blood vessel

D)

the pericardial cavity

47

Fetal skeleton in early stages is formed by

A)

hyaline cartilage

B)

elastic cartilage

C)

bone

D)

muscular tissue

48

Loose connective tissue contains

A)

collagen and elastin fibers

B)

myosin and actin fibers

C)

plasma

D)

all of the above

49

Tendons and ligaments are composed primarily of

A)

adipose tissue

B)

fibrous connective tissue

C)

muscle tissue

D)

loose connective tissue

50

Which of the following types of connective tissue is MISMATCHED with its matrix?

A)

areolar—loosely packed matrix of protein fibers

B)

bone—mineralized matrix

C)

cartilage—highly vascular matrix

D)

blood—liquid matrix

51

Muscle tissue cells are contractile, which means they

A)

are responsible for the production and secretion of enzymes

B)

are specialized in contraction and relaxation

C)

help in the movement of involuntary organs only

D)

All of the above statements are true.

52

A muscle that is not consciously controlled and has a banded appearance would be described as

A)

striated voluntary

B)

striated involuntary

C)

nonstriated voluntary

D)

nonstriated involuntary

53

Movement of food through the digestive tract results from the action of

A)

cardiac muscle

B)

smooth muscle

C)

skeletal muscle

D)

undifferentiated muscle

54

The only type of muscle with multinucleated fibers is

A)

skeletal muscle

B)

cardiac muscle

C)

smooth muscle

D)

visceral muscle

55

The muscle tissue that can be consciously controlled is

A)

smooth

B)

skeletal

C)

intercalated

D)

cardiac

56

Cardiac muscle is found in the wall of the

A)

stomach

B)

intestine

C)

urinary bladder

D)

heart

57

Which one among the following statement about smooth muscle is TRUE?

A)

The smooth muscles are responsible for the movements of the internal organs.

B)

The cells in the smooth muscles have actin, but no striations.

C)

The muscular cells in the smooth muscles are shorter than the skeletal muscles.

D)

All of the above statements are true about the smooth muscle.

58

The type of muscle found in the walls of blood vessels is

A)

cardiac

B)

smooth

C)

striated

D)

voluntary

59

A continuous supply of __________ is necessary for muscle contraction.

A)

ATP

B)

proteins

C)

cells

D)

water

60

Nervous tissue consists predominantly of two cell types:

A)

neurons and fibroblasts

B)

chondrocytes

C)

neurons and neuroglia

D)

smooth muscle and glandular epithelium

61

Which of the following is associated with nervous tissue?

A)

axon

B)

desmosome

C)

intercalated disc

D)

lacuna

62

A unipolar neuron is characterized by the presence of

A)

one dendrite

B)

two dendrites

C)

many dendrites

D)

no dendrites

63

Which of the following is CORRECTLY matched?

A)

neurons—supportive cells of the nervous system

B)

axons—conduct action potentials away from the cell body

C)

neuroglia—the conducting cell of the nervous system

D)

dendrite—rapidly dividing cell

64

What is the function of neuroglial cells in nervous tissue?

A)

support and bind spinal cord and vertebral column together

B)

help nerves grow rapidly

C)

provide nutrients to brain

D)

support and bind nervous tissue together, and they provide nutrients to neurons

65

What is the function of nervous tissue?

A)

maintain and coordinate normal body functions

B)

are responsible for the movements of the body parts

C)

are responsible for cellular division

D)

control the spinal cord

66

In patients suffering from multiple sclerosis, the _____________ of the neurons are destroyed.

A)

axon

B)

neuroglial cells

C)

myelin sheath

D)

cell body

67

Three essential components of most neurons are

A)

simple epithelium, extracellular matrix and nerves

B)

axon, dendrites and cell body

C)

nerve cells, synapse and neuroglia

D)

myelin sheath, node of Ranvier and Schwann cells

68

Which of the following is NOT a characteristic of nervous tissue?

A)

It is found in the brain, spinal cord, and nerves.

B)

It contains the most highly specialized cells.

C)

Its intercellular space is filled with collagen.

D)

Its functional cells are sensitive to changes in their surroundings.

69

Inflammatory reactions usually occur in

A)

epithelium

B)

connective tissue

C)

muscle tissue

D)

nervous tissue

70

The formation of scar tissue is most directly caused by

A)

neutrophils

B)

fibrin

C)

granulation tissue

D)

wound contraction

71

The abnormal death of a tissue is called

A)

necrosis

B)

apoptosis

C)

anaplasia

D)

metaplasia

72

Membranes lining body cavities that lack openings to the outside are called

A)

synovial

B)

mucous

C)

serous

D)

cutaneous

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