- •General Pharmacology
- •Drugs influencing peripheral nervous system Drugs Affecting the Afferent Innervation
- •Cholinomimetic Drugs and Cholinesterase Inhibitors
- •Adrenomimetic Drugs And Sympathomimetics
- •Adrenoblocking Drugs
- •Drugs affecting central nervous system General Anaesthetics
- •Hypnotic Drugs. Ethyl Alcohol
- •Antiepileptic and Antiparkinsonic Drugs
- •Opioid Analgesics
- •(Non-Opioid Analgesics)
- •Antipsychotics, Antidepressants, and Lithium Salts
- •Tranquilizers and Sedative Drugs
- •Psychostimulants, Nootropics, and Analeptics
- •Cardiotonic Drugs
- •Drugs Used for Treatment of Ischemic Heart Disease
- •Antiarrhythmic Drugs
- •Antihypertensive and Hypertensive Drugs
- •Drugs Influencing Secretion of Gastrointestinal Tract
- •Drugs Influencing Motility of Gastrointestinal Tract
- •Diuretic Drugs. Drugs Influencing Uterus. Drugs for Treatment of Goat
- •Drugs Influencing Erythro- and Leucopoesis
- •Antiagregants, Anticoagulants, and Drugs Affecting Fibrinolysis
- •Antimicrobial, antifungal, antiviral, and antiprotosoal drugs Antiseptics and Disinfectants
- •Antibiotics
- •Sulfonamides. Synthetic Antimicrobial Drugs
- •Antitubercular Drugs. Antisyphilitic Drugs
- •Antifungal and Antiviral Drugs
- •Antiprotosoal Drugs
- •Antihelmintic Drugs
- •Drugs influencing metabolism Endocrine Drugs
- •Vitamins
- •Antiallergic and Immunotropic Drugs
- •Antitumoral Drugs. Radioprotectors
- •Contents
Antitumoral Drugs. Radioprotectors
1. Methotrexate (structural analogue of the folic acid which is competitive inhibitor of the duhydrofolatreductase) is prescribed for treatment of the malignant tumour. On which level does methotrexate hinder synthesis of the nucleic acid?
*A. Mononucleotide synthesis
B. Reparation
C. Replication
D. Processing
E. Transcription
2. The preventive radio-protector was given to a worker of a nuclear power station. What mechanism from the follow mentioned is considered to the main mechanism of radioprotection?
*A. Inhibition of free radicals formation
B. Increasing of respiration
C. Activation of oxidation reactions
D. Prevention of tissue’s hypoxia
E. Increasing of tissue blood supply
3. An oncological patient was administered methotre-xate. With the lapse of time the target cells of the tumor lost sensitivity to this drug. We can observe changes in the gene expression of the following enzyme:
*A. Dihydrofolate reduc-tase
B. Desaminase
C. Folate oxidase
D. Folate decarboxylase
E. Thiminase
Contents
General Pharmacology.......................................... |
.......3 |
Drugs Influencing Peripheral Nervous System....................... |
.....15 |
Drugs Affecting the Afferent Innervation.................................... |
.....15 |
Cholinomimetic Drugs and Cholinesterase Inhibitors................. |
.....20 |
M-Cholinoblocking Drugs........................................................... |
.....29 |
N-Cholinoblocking Drugs............................................................ |
.....36 |
Adrenomimetic Drugs and Sympathomimetics........................... |
.....42 |
Adrenoblocking Drugs................................................................. |
.....54 |
Drugs Affecting Central Nervous System................................ |
.....61 |
General Anaesthetics.................................................................... |
.....61 |
Hypnotic Drugs. Ethyl Alcohol.................................................... |
.....63 |
Antiepileptic and Antiparkinsonic Drugs.................................... |
.....66 |
Opioid Analgesics........................................................................ |
.....70 |
Non-Steroid Antiinflammatory Drugs (Non-Opioid Analgesics) |
.....78 |
Antipsychotics, Antidepressants, and Litium Salts...................... |
.....81 |
Tranquilizers and Sedative Drugs................................................ |
.....85 |
Psychostimulants, Nootropics, and Analeptics............................ |
.....87 |
Drugs which Influence Functions of Internal Organs............ |
.....90 |
Drugs Affecting Respiratory System........................................... |
.....90 |
Cardiotonic Drugs........................................................................ |
.....94 |
Drugs Used for Treatment of Ischemic Heart Disease................. |
.....99 |
Antiarrhythmic Drugs.................................................................. |
...106 |
Antihypertensive and Hypertensive Drugs.................................. |
...112 |
Drugs Influencing Secretion of Gastrointestinal Tract................ |
...117 |
Drugs Influencing Motility of Gastrointestinal Tract.................. |
...122 |
Diuretic Drugs. Drugs Influencing Uterus. Drugs for Treatment of Goat........................................................................ |
...125 |
Drugs Influencing Erythro- and Leucopoesis.............................. |
...131 |
Antiagregants, Anticoagulants, and Drugs Affecting Fibrinolysis.................................................................................. |
...134 |
Antimicrobial, Antifungal, Antiviral, and Antiprotosoal Drugs........................................................................................... |
...136 |
Antiseptics and Disinfectants....................................................... |
...136 |
Antibiotics.................................................................................... |
...138 |
Sulfonamides. Synthetic Antimicrobial Drugs............................ |
...141 |
Antitubercular Drugs. Antisyphilitic Drugs................................. |
...143 |
Antifungal and Antiviral Drugs.................................................... |
...145 |
Antiprotosoal Drugs..................................................................... |
...146 |
Antihelmintic Drugs..................................................................... |
...149 |
Drugs Influencing Metabolism.................................................. |
...149 |
Endocrine Drugs.......................................................................... |
...149 |
Vitamins....................................................................................... |
...166 |
Antiallergic and Immunotropic Drugs......................................... |
...169 |
Antitumoral Drugs. Radioprotectors............................................ |
...176 |
