Antiprotosoal Drugs

1. A patient with amebic dysentery was prescribed a drug, which also inhibits the development of the erythrocyte forms of malaria plasmodium. What is it?

*A. Chingaminum

B. Emethini hydrochloridum

C. Tetracyclinum

D. Erythromycinum

E. Chinini sulfas

2. Systemic amebiasis with involvement of intestines, liver, lungs was diagnosed in a 52-year-old patient. What drug should be prescribed?

*A. Metronidasol

B. Tetracyclinum

C. Quiniofone

D. Quingamine

E. Enteroseptol

3. To prevent long-term effects of 4-day malaria a 42-year-old man was prescribed prymaquine in order. On the 3-rd day from the begin of the treatment there appeared stomach and heart pains, dyspepsia, general cyanosis, hemoglobinuria. What could cause such side effects?

*A. Genetic insufficiency of glucose-6-phosphate dehydrogenase

B. Delay preparation excretion with urine

C. Reduced activity of microsomal liver enzymes

D. Accumulation of the medication

E. Potential activity with other preparations

4. Systemic amebiasis with involvement of intestines, liver, and lungs was diagnosed in a 52-year-old patient. What drug should be prescribed?

*A. Metronidasol

B. Quiniofone

C. Quingamine

D. Tetracycline

E. Enteroseptol

5. Undergoing a metronidazole cure a patient drank a small amount of alcohol due to which a severe poisoning developed. What is the cause of the poisoning?

*A. Acetaldehyde accumulation

B. Allergic reaction

C. Neural disorders

D. Cardiovascular collapse

E. Disorder of kidney function

6. The female with dysentery is delivered to infectious unit. By the means of laboratory investigations it is established that originator of disease is Entamoeba histolytica. What drug should be prescribed to female?

*A. Metronidazole

B. Chingaminum

C. Rifampicin

D. Isoniazidum

E. Benzylpenicillinum sodium salt

7. The drug A. is prescribed to patient with ulcer disease of stomach. It is known that drug A. suppress the growth and reproduction of H. pylori. Indicate this drug.

*A. Metronidazole

B. Glauvent

C. Prazosin

D. Corglycon

E. Furosemide

8. Indicate the drug which should not be used with ethyl alcohol, because this drug inhibits the ethanol metabolism.

*A. Metronidazole

B. Reserpine

C. Clophelinum

D. Diazepam

E. Aminazine

9. A 30-year-old patient complains about having abdominal pain and diarrhea for five days; body temperature rise up to 37,5 C along with chills. The day before a patient had been in a forest and drunk from an open water reservoir. Labotatory analyses enabled to make the following diagnosis: amebic dysentery. What is the drug of choice for its treatment?

*A. Metronidazole

B. Phthalazol

C. Furazolidonum

D. Emetine hydrochloride

E. Levomycetin

Antihelmintic Drugs

1. In case of enterobiasis acrihine – the structural analogue of vitamin B₂ – is administered. The synthesis disorder of which enzymes does this drug cause in microorganisms?

*A. FAD-dependent dehydrogenase

B. Cytochromeoxidase

C. NAD-dependent dehydrogenase

D. Katalase

E. Aminotransferase