Antitubercular Drugs. Antisyphilitic Drugs

1. A 35-year-old man under the treatment for pulmonary tuberculosis has acute pain onset of right big toe, swelling, and low-grade fever. The gouty arthritis was diagnosed and high serum uric acid level was found. Which of the following antituberculosis drugs are known for causing high uric acid levels?

*A. Pyrasinamide

B. Aminosalycylic acid

C. Rifampicin

D. Thioacetazone

E. Cycloserine

2. The patient has appealed to the doctor with complaints to red color of urine and tears. It is known, that he is treated from pulmonary tuberculosis. What drug can cause this adverse effect?

*A. Rifampicin

B. Isoniazid

C. Metronidazole

D. Streptomycin sulfate

E. Doxicicline

3. The first-line drug for treatment of tuberculosis is prescribed to 38-year-old patient. It is known that drug causes several adverse effects, which are connected with oppressing of formation of pyridoxal-phosphate. Call this drug.

*A. Isoniazid

B. Rifampicin

C. Doxicicline

D. Metronidazole

E. Chingaminum

4. The neuritis of optic nerve occurred in patient in result of treating with certain antituberculosis drug. Identify this drug.

*A. Isoniazid

B. Ethambutol

C. Kanamycin

D. Rifampicin

E. Streptomycin

5. It is known, that patient A. with pulmonary tuberculosis has hereditary insufficiency of N-acetyltransferase. Indicate the antituberculosis agent which can promote the development of marked toxic effects in this patient.

*A. Isoniazid

B. Streptomycin

C. Ethambutol

D. Rifampicin

E. Sodium salt of PAS

6. In clinical practice tuberculosis is treated with izoniazid – that is an antivitamin able to penetrate into the tuberculosis bacillus. Tuberculostatic effect is induced by the interference with replication processes and oxidation-reduction reactions due to the buildup of pseudo-coenzyme:

*A. NAD

B. TDP

C. FMN

D. CoQ

E. FAD

7. A patient suffering from syphilis has been treated with bismuth preparations. As a result of it some grey spots turned up on the mucous membrane of the oral cavity; nephropathy symptoms were also present. What drug should be used for treatment of bismuth intoxication?

*A. Unithiol

B. Naloxone

C. Bemegride

D. Nalorphine

E. Methylene blue

Antifungal and Antiviral Drugs

1. A child was delivered to a hospital with punctated incrustation (white and yellowish spots) on the mucous tunics of cheeks, palate, and tongue caused by Candida albicans fungus. Which of the following drugs is used for the treatment of the child?

*A. Itraconazolum

B. Gentamycini sulfas

C. Tetracyclini hydrochloridum

D. Cefalexinum

E. Benzylpenicillinum-natrium

2. A stomatologist diagnosed herpetic stomatitis. What is necessary to prescribe for treatment in this case?

*A. Acyclovir

B. Tetracyclinum hydrochloridum

C. Clotrimazolum

D. Itraconazolum

E. Sulfacylum-natrium

3. A patient suffers from candidiasis of mucous membranes of oral cavity. Choose the antibiotics group which is used for treatment of this patient.

*A. Polyene antibiotics

B. Penicillines

C. Macrolides

D. Aminoglycosides

E. Tetracyclines

4. Prescribe the antiviral drug for patient suffering from surrounding herpes.

*A. Acyclovir

B. Ganciclovir

C. Zidovudine

D. Rimantadine

E. Lamivudine