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Step-1 Pharmacology (for students).doc
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Antiagregants, Anticoagulants, and Drugs Affecting Fibrinolysis

1. A patient with thrombophlebitis is administered the complex therapy, which influences different stages of clotforming. Which of the given substances contributes to the restoration of the vascular permeability?

*A. Fibrinolysin

B. Dipiridamol

C. Heparin

D. Neodycumarin

E. Acetylsalicylic acid

2. Some drug had been prescribed to the patient with thromboembolism of veins of lower extremities. In 2 days hemorrhages appeared on his skin. What drug was prescribed to the patient?

*A. Heparin

B. Dipyrodamolum

C. Acidum acetylsalicylicum

D. Neodicumarinum

E. Phenylinum

3. An 8-year-old child is being prescribed for tonsilectomy. The analysis of blood has shown that the time of blood coagulation is increased (up to 7 minutes). What drug should be included (5 days before the operation) into the complex of therapeutic agents of the preparatory period first of all?

*A. Vikasolum

B. Natrii chloridum

C. Acidum aminocapronicum

D. Fibrinogen

E. Etamsylatum

4. A doctor recommended to patient, who had an acute myocardial infarction, to take acidum acetylsalicylicum in the dose 0.25 g once per 2-3 days during 3-4 months. What effect did the doctor count on?

*A. Antiaggregant

B. Antiinflammatory

C. Antipyretic

D. Analgesic

E. Vasodilative

5. Acidum acetylsalicylicum (75 mg, daily) is prescribed to the patient, who had a myocardial infarction. What purpose of this prescribing?

*A. Reduction of thrombocytes aggregation

B. Reduction of inflammation

C. Reduction of pain

D. Dilation of coronary vessels

E. Reduction of body temperature

6. Vicasolum is prescribed to patient during several days before planned surgery concerning an ulcer of stomach. What is mechanism of vicasolum action?

*A. Drug increases blood clotting in result of increasing of prothrombin synthesis

B. Drug decreases the vessels permeability

C. Drug oppresses the fibrinolysis

D. Drug oppresses the aggregation of thrombocymes

E. Drug binds the calcium ions

7. The patient with myocardial infarction is delivered to resuscitation unit. What drug should be administered to patient for prevention of thrombi formation?

*A. Heparin

B. Chingaminum

C. Thyroxine

D. Biseptol-480

E. Dimedrolum

8. Patient with angina pectoris is treated with acetylsalicylic acid in daily dose 100 mg daily. What is the aim of therapy with acetylsalicylic acid in this case?

*A. Inhibition of platelet aggregation

B. Inhibition of blood clotting

C. Dilation of coronary vessels

D. Decrease of prothrombin level

E. Decrease of cholesterol level

Antimicrobial, antifungal, antiviral, and antiprotosoal drugs Antiseptics and Disinfectants

1. To prepare an operative field a doctor used a dichlorinated biguanid

derivative. It is the most active local antiseptic, shows fast and strong bactericidal action on Gram-negative and Gram-positive bacteria. What drug is this?

*A. Chloraminum

B. Viride nitens

C. Furacilinum

D. Phenasalum

E. Unithiolum

2. For the processing of the burn surface of the patient’s skin a specific drug was used. Its antiseptic properties are provided by free oxygen that reacts with organic substances. What drug is this?

*A. Potassium permanganate

B. Furacilinum

C. Chlorhexidini bigluconate

D. Boric acid

E. Sodium hydrocarbonate

3. Profuse foam appeared when dentist put hydrogen peroxide on the mucous of the oral cavity. What enzyme caused such activity?

*A. Catalase

B. Methemoglobinreductase

C. Glucose-6-phosphatdehydrogenase

D. Acetyltransferase

E. Cholinesterase

4. Patient with mercury poisoning was admitted to the toxicological department from the chemical industry. What drug should be used?

*A. Unithiol

B. Enterosorbent

C. Isonitrosin

D. Activated carbon

E. Nalocone

5. A patient with abscess of the cat wound applied to the traumatological department. The wound was washed with 3% hydrogen peroxide to be cleaned from the pus. Foam was not observed. What caused inefficiency of the drug?

*A. Inherited insufficiency of catalase

B. Shallow wound

C. Low concentration of H2O2

D. Inherited insufficiency of erythrocyte’s phosphatdehydrogenase

E. Pus in the wound

6. A patient working at a chemical plant was admitted to the toxicological department with mercury poisoning. What medicine should be used?

*A. Unithiol

B. Enterosorbent

C. Activated carbon

D. Naloxone

E. Isonitrozin

7. A 38-year-old man who poisoned himself with mercury dichloride was taken to the admission room in grave condition. What antidote should be immediately introduced?

*A. Unithiol

B. Nalorphine

C. Dipiroxim

D. Isonitrosine

E. Atropine

8. The patient has applied to doctor with complaints of multiple purulent rashes on the skin of extremities. What antiseptic should be prescribed to him?

*A. Alcoholic solution of iodine

B. Insulin

C. Prednisolon

D. Sibazon

E. Heparin

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