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Step-1 Pharmacology (for students).doc
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Diuretic Drugs. Drugs Influencing Uterus. Drugs for Treatment of Goat

1. The brain edema was developed in patient with a brain trauma in postoperative period. What drug should be prescribed to this patient?

*A. Furosemidum

B. Spironolactonum

C. Amiloridum

D. Dichlothiazidum

E. Urea

2. The brain edema was developed in patient with a brain trauma in postoperative period. What drug should be prescribed to this patient?

*A. Mannitol

B. Spironolactonum

C. Amiloridum

D. Dichlothiazidum

E. Urea

3. A 46-year-old patient with ciliary arrhythmia had pulmonary edema. What diuretic is necessary to use for the treatment of this patient?

*A. Furocemidum

B. Triamterenum

C. Spironolactonum

D. Amiloridum

E. Dichlothiazidum

4. The alternate usage of dichlotiazide, etacrin acid and lasix did not cause marked diuretic effect in the patient with marked peripheral edema. The aldosterone level in the blood is increased. Indicate which drug should be prescribed:

*A. Spironolacton

B. Amilorid

C. Mannitol

D. Urea

E. Clopamid

5. Diuretic drug was prescribed to the patient with hypertension in the course of complex treatment. In a few days blood pressure decreased but signs of hypokaliemia developed. What drug could cause such complications?

*A. Lasix

B. Clophelin

C. Spironolactone

D. Enalapril

E. Triamterene

6. A 42-year-old man suffering from gout has increased level of urinary acid in the blood. Allopurinol was prescribed to decrease the level of urinary acid. Competitive inhibitor of what enzyme is allopurinol?

*A. Xanthinoxidase

B. Hypoxantinphosphoribosil-transferase

C. Guaninedeaminase

D. Adenosinedeaminase

E. Adeninephosphoribosiltransferase

7. A doctor administered Allopurinol to a 26-year-old man with symptoms of gout. What pharmacological action of Allopurinol ensures therapeutic effect?

*A. Inhibiting uric acid synthesis

B. General antiinflammatory effect

C. Inhibiting leucocyte migration into the joint

D. Increasing uric acid excretion

E. General analgesic effect

8. Of the following agents, which is best avoided in a patient with a history of chronic congestive heart failure?

*A. Mannitol

B. Amilorode

C. Hydrochlorthiazide

D. Ethacrinic acid

E. Spironolactone

9. Furosemide inhibits the sodium-potassium dichloride (Na+, K+, 2Cl-) co-transporters that are located in the:

*A. Ascending limb of the loop of Henle

B. Collecting duct

C. Descending limb of the loop of henle

D. Proximal tubule

E. Distal convoluted tubule

10. Hyperkalemia is a contraindication to the use of which of the following drugs?

*A. Spironolactone

B. Ethacrynic acid

C. Chlorthalidone

D. Furosemide

E. Hydrochlorothiazide

11. A reduction in insulin release from the pancreas may caused by which of the following diuretics?

*A. Hydrochlorothiazide

B. Triamterene

C. Spironolactone

D. Ethacrynic acid

E. Amiloride

12. Acute uric acid nephropathy, which is characterized by the acute overproduction of uric acid and by extreme hyperuricemia, can best be prevented with which of the following?

*A. Allopurinol

B. Ethamidum

C. Antidiuretic hormone

D. Amiloride

E. Sodium chloride

13. A patient with nephrotic diabetes insipidus is best treated with which of the following?

*A. Hydrochlorothiazide

B. Triamterene

C. Furosemide

D. Spironolactone

E. Ethacrynic acid

14. A 50-year-old male with pitting edema of the ankles develops gynecomastia and erectile dysfunction while being treated with which of the following agents?

*A. Spironolactone

B. Furosemide

S. Hydrochlorothiazide

D. Triamterene

E. Amilorode

15. From the list of diuretic drugs choose the agent that is most useful for the treatment of acute pulmonary edema:

*A. Furosemide

B. Hydrochlorothiazide

C. Amiloride

D. Spironolactone

E. Triamterene

16. From the list of diuretic drugs choose the agent that is most useful for the treatment of acute hypercalcemia:

*A. Hydrochlorothiazide

B. Amiloride

C. Furosemide

D. Spironolactone

E. Triamterene

17. From the list of diuretic drugs choose the agent that is most useful for the treatment of essential hypertension:

*A. Hydrochlorothiazide

B. Amiloride

C. Furosemide

D. Spironolactone

E. Triamterene

18. The most widely used agent for the treatment of acute gouty arthritis is:

*A. Colchicine

B. Allopurinol

C. Probenecid

D. Indomethacin

E. Phenylbutazone

19. The mechanism by which probenecid lowers plasma levels of uric acid is:

*A. By inhibiting proximal tubular reabsorption of uric acid

B. By inhibiting production of uric acid in the liver

C. By promoting tubular secretion of uric acid

D. By inhibiting breakdown of purines to uric acid

20. Allopurinol reduces serum urate levels by:

*A. Inhibiting uric acid synthesis

B. Promoting the active secretion of uric acid in kidneys

C. Impairing renal urate reabsorption

D. Decreasing metabolism of uric acid

21. The solution of some drug was introduced to pregnant woman for prevention of premature delivery. This drug is also known as anticonvulsant, hypotensive, cholagogic, and laxative drug. Contraction of uterus and pain stopped, soothing effect occurred. What drug has been prescribed to woman?

*A. Magnesii sulfas

B. Oxytocinum

C. Fenoterolum

D. Ergometrini maleas

E. Salbutamolum

22. A patient with chronic cardiovascular insufficiency had signs of edema of lungs. What diuretic should be prescribed to the patient for the fast elimination of this condition?

*A. Furosemide

B. Spironactone

C. Clopamidum

D. Diacarbum (acetazolamidum)

E. Triamterenum

23. The significant decrease of blood pressure has developed in patient in result of diuretic overdose. Choose the group of hypertensive drugs which is preferable for using to this patient.

*A. Plasma substitutes

B. Cardiac glycosides

C. Analeptics

D. Adrenomimetics

E. N-cholinomimetics

24. The patient with pulmonary edema is delivered to resuscitation unit. What drug should be administered to patient for decreasing of blood pressure in small circle of circulation and for decreasing of volume of circulating blood?

*A. Furosemide

B. Unithiolum

C. Sulfacyl-sodium

D. Metronidazole

E. Acetylcysteine

25. The ascites has developed in patient with cirrhosis. Indicate the drug which should be administered to him for excretion of humor from body.

*A. Furosemide

B. Potassium chloride

C. Heparin

D. Atropine sulfate

E. Aminazine

26. Identify laxative drug which can be used for reflex increasing of uterus contractions in cases of insufficiently labor activity.

*A. Castor oil

B. Bisacodyl

C. Magnesium sulfate

D. Vaseline

E. Sustac

27. In spite of treatment with cardiotonics and thiazide diuretic a patient suffering from chronic cardiac failure still presents with edemata and faces a risk of ascites. What medication should be administered in order to increase the diuretic effect of the above mentioned drugs?

*A. Spironolactone

B. Amiloride

C. Furosemide

D. Clopamide

E. Manithol

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