Drugs Influencing Motility of Gastrointestinal Tract

1. Metoclopramide has antiemetic properties because it:

*A. Is a central nervous system dopamine-receptor antagonist

B. Lowers esophageal sphincter pressure

C. Accelerates gastric emptying time

D. Has sedative properties

E. Has sedative properties

2. The steatorrhea of pancreatic insufficiency can best be treated by:

*A. Pancrelipase

B. Misoprostol

C. Bile salts

D. Cimetidine

E. Secretin

3. A 20-year-old woman goes to the emergency department, stating that within the past hour she ingested “a handful of sleeping pills.” She is still awake. Which of the following drugs can be given to induce vomiting?

*A. Apomorphini hydrochloridum

B. Metoclopramide

C. Morphine

D. Promethazine

E. Ondansetron

4. A 62-year-old woman on hemodialysis is scheduled for a screening colonoscopy. Which should be prescribed for her colonic preparation?

*A. Magnesium sulfatum

B. Omeprasolum

C. Magnesium oxydum

D. Ranitidinum

E. Cholosasum

5. A 37-year-old man was admitted to the surgical department with symptoms of acute pancreatitis: vomiting, diarrhea, bradycardia, hypotension, weakness, dehydration of the organism. What medicine should be used first of all?

*A. Contrical

B. Platyphylline

C. Etaperazine

D. Ephedrine

E. No-spa

6. A forty-eight year-old woman receives epidural anesthesia for vaginal hysterectomy. In recovery room, a fentanyl infusion was begun epidurally for relief of postoperative pain. About six hours later, she began to complain of nausea and had two episodes of vomiting. How could the nausea and vomiting best be relieved?

*A. Administer ondansetron

B. Sedate the patient with midazolam (Versed)

C. Withhold oral administration of fluids

D. Discontinue the fentanyl (Sublimaze) infusion

7. A 28 year-old woman at full-term pregnancy became a candidate for cesarean section because of dystocia cause by fetal malposition. According to clinical standards, she was about 50 pounds overweight. General anesthesia was chosen for the surgical procedure. (Dystocia: difficult labor caused by the contraction of an area of circular muscle fibers, which may occur in various levels of the parturient uterus). What would be the best drug to be given as preanesthetic medication to promote gastric emptying?

*A. Metoclopramide (Reglan)

B. Ipratropium (Atrovent)

C. Atropine

D. Glycopyrrolate (Robinul)

8. In esophagitis, elevation of the head of the bed, abstinence from ethanol and tobacco, and small frequent meals are all useful adjunctive therapeutic measures. Other useful therapy may include all of the following except:

*A. Amitriptyline

B. Metoclopramide

C. Bethanechol

D. Cimetidine

E. Omeprazole

9. An ambulance took a patient to a hospital in serious condition (nausea, vomiting). It is established that the day before he celebrated a wedding with the family. The initial diagnosis is food toxicoinfection. What drug is it necessary to use first of all?

*A. Magnesii sulfas

B. Butamidum

C. Clophelinum

D. Dimedrolum

E. Adrenalini hydrochloridum

10. The intestine colic has developed in hypertensive patient. Choose the drugs group which is most rational for interruption of colic in this patient.

*A. Miotropic spasmolytics

B. Cholinesterase inhibitors

C. Sympathomimetics

D. M-cholinoblockers

E. Adrenomimetics

11. The laxative drug having osmotic activity was prescribed to patient. What is this drug?

*A. Magnesium sulfate

B. Bisacodyl

C. Vaseline

D. Isapheninum

E. Sustac

12. The laxative drug was prescribed to patient with brain edema. Indicate this drug.

*A. Magnesium sulfate

B. Cortex of Buckthorn

C. Bisacodyl

D. Castor oil

E. Liquid paraffin