Antipsychotics, Antidepressants, and Lithium Salts

1. The patient was treated medically for psychosis for 2 weeks. Patient’s condition improved but rigidity, tremor, and hypokinesia developed. Which of the drugs can cause such complications?

*A. Aminazine

B. Imipramine

C. Chlordiazepoxide

D. Diphenine

E. Sydnocarb

2. To eliminate delirium and hallucinations of a patient with schizophrenia a doctor used aminazine. What is the mechanism of antipsychotic action of the drug?

*A. Blockade of adrenergic and dopaminergic processes in the CNS

B. Stimulation of adrenergic and dopaminergic processes in the CNS

C. Stimulation of cholinergic processes in the CNS

D. Blockade of cholinergic processes in the CNS

E. Blockade of the inverse neuronal capture of catecholamines

3. A patient with manic-depressive psychosis and manifestations of depression complains of anxiety and fear. What antidepressant with accompanying psychosedative effect is it necessary to prescribe?

*A. Amitriptylinum

B. Imizinum

C. Sydnocarbum

D. Nialamidum

E. Phenazepamum

4. A drug shows a strong, fast, but not long-term neuroleptic action. It potentiates the action of analgesic, soporific agents, alcohol. It has antishock and antiemetic action. It belongs to buthyrophenone derivatives. What is this drug?

*A. Droperidolum

B. Triphthazinum

C. Aminazinum

D. Clozepinum

E. Sulpiridum

5. A patient developed symptoms of medicinal parkinsonism after psychosis treatment in a mental hospital. What drug had been used for his treatment?

*A. Aminazinum

B. Mezapamum

C. Natrii bromidum

D. Lithii carbonas

E. Nialamidum

6. Acute heart attack is accompanied by retrosternal pain. Ineffectiveness of preliminary taken drugs has made the doctor to perform neurolepanalgesia. What neuroleptic is used for this type of anesthesia?

*A. Droperidolum

B. Metherazinum

C. Haloperidolum

D. Reserpinum

E. Aminazinum

7. A 38-year-old man suffers from schizophrenia. He has come to a doctor with complaints of disorder of coordination and movements, tremor in his hands, drowsiness. The patient has been taking psychotropic drugs for a long period of time. What group of drugs can lead to such complex of symptoms?

*A. Neuroleptics

B. Analgesics

C. Antidepressants

D. Psychomotor stimulants

E. Adaptogens

8. A patient with maniac-depressive psychosis demonstrates inhibition of mental and impellent activity, agitation, depression. What drug is it necessary to prescribe in order to relieve pathological depression?

*A. Amitriptylinum

B. Sydnocarbum

C. Coffeinum-natrii benzoas

D. Pyracetamum

E. Triphthazinum

9. A man is kept under dispensary observation in a psychoneurologic clinic because of chronic alcoholism. Alcohol abuse led to acute psychosis. What drug can be expediently used?

*A. Aminazinum

B. Atropine

C. Pentaminum

D. Hygronium

E. Adrenaline

10. What neuroleptic is characterized by the following properties: phenothiazine derivative, blocks postsynaptic dopamine and adrenergic receptors in the CNS, provides a sedative effect on the CNS, prolonged application can induce extrapyramidal abnormalities and neuroleptic syndrome?

*A. Aminazinum

B. Diazepamum

C. Triphthazinum

D. Droperidolum

E. Haloperidolum

11. A woman tried to commit suicide. A psychiatrist detected a condition of endogenous depression of this patient. What medication is expedient to prescribe to the patient for the course of treatment?

*A. Amitriptylinum

B. Sydnocarbum

C. Aethimizolum

D. Pyracetamum

E. Coffeinum-natrii benzoas

12. A patient with sxhzophrenia takes aminazine. Which of the listed pharmacodynamic effects is the basic one in this case?

*A. Antipsychotic

B. Antiemetic

C. Hypothermic

D. Muscle relaxing

E. Hypotensive

13. An ambulance has delivered to a hospital a patient, who tried to commit suicide in the condition of severe depression. The diagnosis: depressive psychosis. The drug of which pharmacological group is necessary to prescribe to the patient?

*A. Antidepressants

B. Sedatives

C. Neuroleptics

D. Tranquilizers

E. Lithium salts

14. A patient suffering from Parkinson’s disease needs additional treatment concerning accompanied pathology. Indicate the group of drugs which can cause aggravation of Parkinson’s disease in this patient?

*A. Antipsychotic drugs (neuroleptics)

B. Tranquilizers

C. Hypnotics

D. M-cholinoblockers

E. Antidepressants

15. First aid brigade has delivered to a hospital the patient with obvious psychomotor disturbances. What drug should be administered to the patient?

*A. Aminazine

B. Piracetam

C. Rifampicin

D. Heparin

E. Bisacodyl

16. The surgery patient needs the neuroleptanesthesia. What drug is most commonly used for neuroleptanesthesia together with fentanyl?

*A. Droperidol

B. Cholosasum

C. Salbutamol

D. Pilocarpine

E. Fraxiparine

17. Pharmacological effects of antidepressants are based upon blocking (inhibiting) the enzyme that acts as a catalyst for the breakdown of biogenic amines noradrenaline and serotonin in the mitochondria of cephalic neurons. What enzyme takes part in this process?

*A. Monoamine oxidase

B. Lyase

C. Transaminase

D. Peptidase

E. Decarboxylase