CST 2015 / Phospholipase
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CELL SIGNALING TECHNOLOGY |
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Phospholipase Signaling
GPCR
Gβγ
Gα
GTP
EGFR
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Arachidonic |
PLCβ3 |
PIP2 |
PLCγ1 |
Acid |
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CaMKII |
DAG |
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cPLA2 |
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PKC |
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IP3 |
cPLA2 |
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Mnk1 |
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MAPK |
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Prostaglandins |
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p38 MAPK |
Leukotrienes |
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Cascade |
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Lipoxins |
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Ca++ |
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Ca++ |
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Endoplasmic |
IP3R |
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Reticulum |
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Ca++ |
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Ca++ |
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Pathway Diagram Keys
Kinase |
Enzyme |
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G-protein |
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Direct Inhibitory |
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Tentative Inhibitory |
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Translocation |
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Phosphatase |
pro-apoptotic |
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Acetylase |
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Modification |
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Modification |
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Transcriptional |
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Multistep Stimulatory |
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Separation of Subunits |
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Stimulatory Modification |
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Transcription Factor |
pro-survival |
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Deacetylase |
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Modification |
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or Cleavage Products |
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Transcriptional |
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Caspase |
GAP/GEF |
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Multistep Inhibitory |
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Joining of Subunits |
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Inhibitory Modification |
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Ribosomal subunit |
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Modification |
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Receptor |
GTPase |
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Direct Stimulatory |
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Tentative Stimulatory |
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Modification |
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Modification |
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