- •ICU Protocols
- •Preface
- •Acknowledgments
- •Contents
- •Contributors
- •1: Airway Management
- •Suggested Reading
- •2: Acute Respiratory Failure
- •Suggested Reading
- •Suggested Reading
- •Website
- •4: Basic Mechanical Ventilation
- •Suggested Reading
- •Suggested Reading
- •Websites
- •Suggested Reading
- •Websites
- •7: Weaning
- •Suggested Reading
- •8: Massive Hemoptysis
- •Suggested Reading
- •9: Pulmonary Thromboembolism
- •Suggested Reading
- •Suggested Reading
- •Websites
- •11: Ventilator-Associated Pneumonia
- •Suggested Readings
- •12: Pleural Diseases
- •Suggested Reading
- •Websites
- •13: Sleep-Disordered Breathing
- •Suggested Reading
- •Websites
- •14: Oxygen Therapy
- •Suggested Reading
- •15: Pulse Oximetry and Capnography
- •Conclusion
- •Suggested Reading
- •Websites
- •16: Hemodynamic Monitoring
- •Suggested Reading
- •Websites
- •17: Echocardiography
- •Suggested Readings
- •Websites
- •Suggested Reading
- •Websites
- •19: Cardiorespiratory Arrest
- •Suggested Reading
- •Websites
- •20: Cardiogenic Shock
- •Suggested Reading
- •21: Acute Heart Failure
- •Suggested Reading
- •22: Cardiac Arrhythmias
- •Suggested Reading
- •Website
- •23: Acute Coronary Syndromes
- •Suggested Reading
- •Website
- •Suggested Reading
- •25: Aortic Dissection
- •Suggested Reading
- •26: Cerebrovascular Accident
- •Suggested Reading
- •Websites
- •27: Subarachnoid Hemorrhage
- •Suggested Reading
- •Websites
- •28: Status Epilepticus
- •Suggested Reading
- •29: Acute Flaccid Paralysis
- •Suggested Readings
- •30: Coma
- •Suggested Reading
- •Suggested Reading
- •Websites
- •32: Acute Febrile Encephalopathy
- •Suggested Reading
- •33: Sedation and Analgesia
- •Suggested Reading
- •Websites
- •34: Brain Death
- •Suggested Reading
- •Websites
- •35: Upper Gastrointestinal Bleeding
- •Suggested Reading
- •36: Lower Gastrointestinal Bleeding
- •Suggested Reading
- •37: Acute Diarrhea
- •Suggested Reading
- •38: Acute Abdominal Distension
- •Suggested Reading
- •39: Intra-abdominal Hypertension
- •Suggested Reading
- •Website
- •40: Acute Pancreatitis
- •Suggested Reading
- •Website
- •41: Acute Liver Failure
- •Suggested Reading
- •Suggested Reading
- •Websites
- •43: Nutrition Support
- •Suggested Reading
- •44: Acute Renal Failure
- •Suggested Reading
- •Websites
- •45: Renal Replacement Therapy
- •Suggested Reading
- •Website
- •46: Managing a Patient on Dialysis
- •Suggested Reading
- •Websites
- •47: Drug Dosing
- •Suggested Reading
- •Websites
- •48: General Measures of Infection Control
- •Suggested Reading
- •Websites
- •49: Antibiotic Stewardship
- •Suggested Reading
- •Website
- •50: Septic Shock
- •Suggested Reading
- •51: Severe Tropical Infections
- •Suggested Reading
- •Websites
- •52: New-Onset Fever
- •Suggested Reading
- •Websites
- •53: Fungal Infections
- •Suggested Reading
- •Suggested Reading
- •Website
- •55: Hyponatremia
- •Suggested Reading
- •56: Hypernatremia
- •Suggested Reading
- •57: Hypokalemia and Hyperkalemia
- •57.1 Hyperkalemia
- •Suggested Reading
- •Website
- •58: Arterial Blood Gases
- •Suggested Reading
- •Websites
- •59: Diabetic Emergencies
- •59.1 Hyperglycemic Emergencies
- •59.2 Hypoglycemia
- •Suggested Reading
- •60: Glycemic Control in the ICU
- •Suggested Reading
- •61: Transfusion Practices and Complications
- •Suggested Reading
- •Websites
- •Suggested Reading
- •Website
- •63: Onco-emergencies
- •63.1 Hypercalcemia
- •63.2 ECG Changes in Hypercalcemia
- •63.3 Superior Vena Cava Syndrome
- •63.4 Malignant Spinal Cord Compression
- •Suggested Reading
- •64: General Management of Trauma
- •Suggested Reading
- •65: Severe Head and Spinal Cord Injury
- •Suggested Reading
- •Websites
- •66: Torso Trauma
- •Suggested Reading
- •Websites
- •67: Burn Management
- •Suggested Reading
- •68: General Poisoning Management
- •Suggested Reading
- •69: Syndromic Approach to Poisoning
- •Suggested Reading
- •Websites
- •70: Drug Abuse
- •Suggested Reading
- •71: Snakebite
- •Suggested Reading
- •72: Heat Stroke and Hypothermia
- •72.1 Heat Stroke
- •72.2 Hypothermia
- •Suggested Reading
- •73: Jaundice in Pregnancy
- •Suggested Reading
- •Suggested Reading
- •75: Severe Preeclampsia
- •Suggested Reading
- •76: General Issues in Perioperative Care
- •Suggested Reading
- •Web Site
- •77.1 Cardiac Surgery
- •77.2 Thoracic Surgery
- •77.3 Neurosurgery
- •Suggested Reading
- •78: Initial Assessment and Resuscitation
- •Suggested Reading
- •79: Comprehensive ICU Care
- •Suggested Reading
- •Website
- •80: Quality Control
- •Suggested Reading
- •Websites
- •81: Ethical Principles in End-of-Life Care
- •Suggested Reading
- •82: ICU Organization and Training
- •Suggested Reading
- •Website
- •83: Transportation of Critically Ill Patients
- •83.1 Intrahospital Transport
- •83.2 Interhospital Transport
- •Suggested Reading
- •84: Scoring Systems
- •Suggested Reading
- •Websites
- •85: Mechanical Ventilation
- •Suggested Reading
- •86: Acute Severe Asthma
- •Suggested Reading
- •87: Status Epilepticus
- •Suggested Reading
- •88: Severe Sepsis and Septic Shock
- •Suggested Reading
- •89: Acute Intracranial Hypertension
- •Suggested Reading
- •90: Multiorgan Failure
- •90.1 Concurrent Management of Hepatic Dysfunction
- •Suggested Readings
- •91: Central Line Placement
- •Suggested Reading
- •92: Arterial Catheterization
- •Suggested Reading
- •93: Pulmonary Artery Catheterization
- •Suggested Reading
- •Website
- •Suggested Reading
- •95: Temporary Pacemaker Insertion
- •Suggested Reading
- •96: Percutaneous Tracheostomy
- •Suggested Reading
- •97: Thoracentesis
- •Suggested Reading
- •98: Chest Tube Placement
- •Suggested Reading
- •99: Pericardiocentesis
- •Suggested Reading
- •100: Lumbar Puncture
- •Suggested Reading
- •Website
- •101: Intra-aortic Balloon Pump
- •Suggested Reading
- •Appendices
- •Appendix A
- •Appendix B
- •Common ICU Formulae
- •Appendix C
- •Appendix D: Syllabus for ICU Training
- •Index
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77.2Thoracic Surgery
Step 1: Take care of immediate postoperative issues
¥Immediate concerns include assessment of oxygenation, volume status, cardiovascular support, provision of ventilatory support if needed to ensure adequate oxygen delivery and status of chest drains that accompany the patient from the operating room.
¥Special concerns apply to pain control, which is especially important, as pain will limit respiratory effort and can also precipitate delirium and agitation.
Step 2: Be cognizant of potential problems following thoracotomy
¥Poor respiratory effort and sputum retention (chest wall trauma and pain)
¥Atelectasis, pneumonia, and sepsis
¥Alveolar and minor bronchial air leaks
¥Localized or generalized pulmonary edema
¥Intercostal, pulmonary, or bronchial vessel hemorrhage
¥Cardiac arrhythmias, myocardial infarction, and heart failure
¥Pulmonary and systemic embolism
¥Chest wall hematoma, wound infection, and wound dehiscence
Step 3: Be cognizant of potential problems following lung resection
¥Respiratory insufÞciency due to extensive lung resection
¥Bronchopleural Þstula and massive air leak
¥Early and late mediastinal shift
¥Atrial Þbrillation and other supraventricular arrhythmias
¥Torsion of lobe or segment
¥Cardiac herniation (usually after pneumonectomy with a partial pericardium excision, when the heart herniates through a gap in the pericardium; may be manifested by supraventricular arrhythmias and/or severe hypotension)
¥Residual venous or arterial lung infarction
¥Blood loss into the pleural space, mediastinum, or bronchus
¥Bronchial obstruction from accumulated secretions, blood, and pus
¥Empyema following air leaks, insufÞcient lung volume, or overwhelming sepsis
¥Paradoxical chest wall movement following extensive rib resection
¥Pulmonary hypertension and acute right-sided heart failure
Step 4: Get a chest X-ray in the hypoxic patient
¥In all postoperative thoracic surgery patients who are hypoxic on arrival, after a careful physical examination, urgent chest X-rays should be requested.
¥A daily chest radiograph must be performed in unstable patients, to conÞrm endotracheal, nasogastric, and chest tube placement, as well as to identify any pneumothorax, mediastinal shift, or signiÞcant atelectasis.
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Step 5: Assess chest drain sites and amount of drainage
¥Hourly output from chest tubes should be recorded, and the operative team should be notiÞed if drainage is greater than 100 mL/h for more than 4 h, or if greater than 200 mL of drainage is recorded in any 1-h observation period.
¥Expected chest tube drainage from major thoracic procedures in the Þrst 24 h is roughly 300Ð600 mL, tapering to less than 200 mL by the second day.
¥Daily chest radiographs are usually obtained while chest tubes are in place.
¥Once all air leaks resolve and drainage is minimal (<100 mL/24 h), chest tubes may be removed during the expiratory phase of ventilation or while the patient performs a Valsalva maneuver.
¥After pneumonectomy, surgeons usually keep the intercostals drain on the operated side clamped so that the ßuid Þlls the pneumonectomy space and maintains the mediastinum central.
¥This drain may be occasionally unclamped for a short period to note whether there is bleeding.
¥The drain may need to be unclamped if there is very rapid accumulation of ßuid in the pneumonectomy space, manifested by dyspnea, mediastinal shift to the opposite side, high jugular venous pressure (JVP), or central venous pressure. This may be mistaken for congestive cardiac failure.
Step 6: Address airway concerns and plan for extubation
¥Extubation can often be accomplished in the operating room, but continued ventilation may be necessary in the presence of concurrent cardiac illness, inability to protect the airway, malnutrition, or coexisting lung disease.
¥Ideally, the patient should be awake and following instructions and have an adequate gag reßex (signifying airway protection) and cough (for secretion clearance).
Step 7: Control pain
¥Adequate pain control is important not only to ensure patient comfort but also to avoid potential cardiac and pulmonary complications. Early pain management is also important in an effort to reduce the chances of developing long-term postthoracotomy pain.
¥Various options exist for pain management. They include systemic analgesics, neuraxial opioids, and local anesthetics via the epidural route, regional anesthesia such as intercostal and paravertebral nerve blocks, and adjuvant therapies such as transcutaneous electrical nerve stimulation (TENS) or applied heat. Exercise caution when using TENS in the patient with the temporary pacemaker in situ as it may interfere with sensing function of the pacemaker.
¥The mainstay of postoperative pain control is systemic analgesics in the form of opioids. Agents such as morphine and fentanyl are frequently used, with the intravenous route providing the most predictable responses. Opioid side effects remain the greatest issue, with respiratory depression, nausea, vomiting, and ileus being the most common.
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¥Nonopiate medications such as paracetamol and nonsteroidal anti-inßammatory drugs (NSAIDs) are reasonable adjuncts to the opioids. Because NSAIDs may exacerbate renal dysfunction, it is necessary to exercise caution when using them in the presence of underlying renal insufÞciency.
¥Neuraxial opioids and local anesthetics via the epidural route provide excellent regional pain control. Epidural catheters are the preferred route, and when local anesthetics, either with or without opioids, are infused in this manner, the incidence of pulmonary complications decreases relative to that with systemic opioids.
¥In addition, patients requiring prolonged postoperative mechanical ventilation may beneÞt from the centrally acting a-adrenergic agonist, dexmedetomidine, as an analgosedative.
Step 8: Optimize fluid balance
¥Fluid management in the postoperative period requires special attention due to the high risk for pulmonary edema. The choice of ßuid for resuscitation is left to the discretion of the caregiver, as there is no known difference in outcome with use of either isotonic crystalloid or colloid.
¥Traditional markers of perfusion help determine if a patient is adequately vol- ume-resuscitated. These include urine output (usually >0.5 mL/kg/h), mental status, blood pressure, heart rate, blood lactate level, capillary reÞll time, venous oxygen saturation, Þlling pressures, and cardiac performance.
¥Ideally, the clinician should limit crystalloid infusion to 20 mL/kg for the Þrst 24 h.
Step 9: Start respiratory therapy
¥Thoracic surgical patients often have signiÞcant underlying chronic obstructive pulmonary disease, impaired mucociliary clearance, excessive secretions, and/or increased closing volumes, all of which predispose to atelectasis.
¥The respiratory therapist plays an important role in providing secretion management and performing chest physiotherapy (percussion and vibration) and incentive spirometry.
¥Other modalities supporting recovery include adequate hydration, aerosolized bronchodilators, humidiÞed oxygen, and early identiÞcation and treatment of infection of the tracheobronchial tree.
¥Chest physiotherapy should begin as soon as the patient has recovered sufÞciently from anesthesia to cooperate.
Step 10: Manage bronchopleural fistula
¥Early postoperative bronchopleural Þstula in a pneumonectomy patient is a surgical emergency. The typical presentation is sudden expectoration of copious amounts of pink, frothy sputum, which may be misdiagnosed as pulmonary
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edema. Further management will likely include bronchoscopy to assess the stump closure and immediate reoperation if a leak is detected.
¥A double-lumen tube may need to be introduced to prevent soiling of the opposite lung by contents of the pleural space and to prevent loss of tidal ventilation through the Þstula.
¥Always insert an intercostal drain on the side of the Þstula and keep it draining at all times.
Step 11: Manage postoperative hypoxemia
¥Postoperative hypoxemia is common and may be due to hypoventilation, atelectasis, aspiration, sepsis, acute respiratory distress syndrome, pneumonia, or pulmonary embolization.
¥Noninvasive ventilation may be useful to treat respiratory failure after lung surgery.
¥If pulmonary emboli are suspected, manage the patient accordingly (refer to Chap. 5).
¥Systemic tumor emboli, though uncommon, may be seen after pulmonary resections for primary bronchogenic carcinomas or metastatic sarcomas.
¥Meticulous attention must be given to prevent dehydration, overtransfusion, and infection.
Step 12: Address special concerns in esophageal surgery
¥Patients who undergo esophageal resection for carcinoma tend to be malnourished and have complications, including atelectasis, pneumonia, aspiration, and retained secretions.
¥Noninvasive ventilation should be avoided after esophageal surgery and surgery involving upper gastrointestinal anastomoses. If the patient needs ventilatory support, intubate the patient.
¥One-third of patients experience respiratory complications. The most dreaded complication of esophageal surgery is leakage from the surgical site. Factors impacting the incidence include high estimated intraoperative blood loss, cervical location of the anastomosis, and the development of postoperative acute respiratory distress syndrome.
¥Anastomotic dehiscence or ischemia of the gastric tube should be suspected when the following signs/symptoms appear: hydropneumothorax, bronchospasm, atrial Þbrillation, dyspnea, hypotension, raised lactate levels, and tachycardia.
¥Mortality associated with anastomotic leaks is historically high, but with improved surgical techniques, the patients now have a more promising outcome.
¥Intraoperative nasojejunal tube placement or jejunostomy is vital to maintain enteral nutrition throughout the postoperative period.
¥A multimodal approach including epidural analgesia, judicious ßuid administration, early mobilization, and enteral nutrition contributes to a good outcome.