- •Preface to the 3rd edition
- •General Pharmacology
- •Systems Pharmacology
- •Therapy of Selected Diseases
- •Subject Index
- •Abbreviations
- •General Pharmacology
- •History of Pharmacology
- •Drug and Active Principle
- •The Aims of Isolating Active Principles
- •European Plants as Sources of Effective Medicines
- •Drug Development
- •Congeneric Drugs and Name Diversity
- •Oral Dosage Forms
- •Drug Administration by Inhalation
- •Dermatological Agents
- •From Application to Distribution in the Body
- •Potential Targets of Drug Action
- •External Barriers of the Body
- •Blood–Tissue Barriers
- •Membrane Permeation
- •Binding to Plasma Proteins
- •The Liver as an Excretory Organ
- •Biotransformation of Drugs
- •Drug Metabolism by Cytochrome P450
- •The Kidney as an Excretory Organ
- •Presystemic Elimination
- •Drug Concentration in the Body as a Function of Time—First Order (Exponential) Rate Processes
- •Time Course of Drug Concentration in Plasma
- •Time Course of Drug Plasma Levels during Repeated Dosing (A)
- •Time Course of Drug Plasma Levels during Irregular Intake (B)
- •Accumulation: Dose, Dose Interval, and Plasma Level Fluctuation (A)
- •Dose–Response Relationship
- •Concentration–Effect Curves (B)
- •Concentration–Binding Curves
- •Types of Binding Forces
- •Agonists—Antagonists
- •Other Forms of Antagonism
- •Enantioselectivity of Drug Action
- •Receptor Types
- •Undesirable Drug Effects, Side Effects
- •Drug Allergy
- •Cutaneous Reactions
- •Drug Toxicity in Pregnancy and Lactation
- •Pharmacogenetics
- •Placebo (A)
- •Systems Pharmacology
- •Sympathetic Nervous System
- •Structure of the Sympathetic Nervous System
- •Adrenergic Synapse
- •Adrenoceptor Subtypes and Catecholamine Actions
- •Smooth Muscle Effects
- •Cardiostimulation
- •Metabolic Effects
- •Structure–Activity Relationships of Sympathomimetics
- •Indirect Sympathomimetics
- •Types of
- •Antiadrenergics
- •Parasympathetic Nervous System
- •Cholinergic Synapse
- •Parasympathomimetics
- •Parasympatholytics
- •Actions of Nicotine
- •Localization of Nicotinic ACh Receptors
- •Effects of Nicotine on Body Function
- •Aids for Smoking Cessation
- •Consequences of Tobacco Smoking
- •Dopamine
- •Histamine Effects and Their Pharmacological Properties
- •Serotonin
- •Vasodilators—Overview
- •Organic Nitrates
- •Calcium Antagonists
- •ACE Inhibitors
- •Drugs Used to Influence Smooth Muscle Organs
- •Cardiac Drugs
- •Cardiac Glycosides
- •Antiarrhythmic Drugs
- •Iron Compounds
- •Prophylaxis and Therapy of Thromboses
- •Possibilities for Interference (B)
- •Heparin (A)
- •Hirudin and Derivatives (B)
- •Fibrinolytics
- •Intra-arterial Thrombus Formation (A)
- •Formation, Activation, and Aggregation of Platelets (B)
- •Inhibitors of Platelet Aggregation (A)
- •Presystemic Effect of ASA
- •Plasma Volume Expanders
- •Lipid-lowering Agents
- •Diuretics—An Overview
- •NaCl Reabsorption in the Kidney (A)
- •Aquaporins (AQP)
- •Osmotic Diuretics (B)
- •Diuretics of the Sulfonamide Type
- •Potassium-sparing Diuretics (A)
- •Vasopressin and Derivatives (B)
- •Drugs for Gastric and Duodenal Ulcers
- •Laxatives
- •Antidiarrheal Agents
- •Drugs Affecting Motor Function
- •Muscle Relaxants
- •Nondepolarizing Muscle Relaxants
- •Depolarizing Muscle Relaxants
- •Antiparkinsonian Drugs
- •Antiepileptics
- •Pain Mechanisms and Pathways
- •Eicosanoids
- •Antipyretic Analgesics
- •Nonsteroidal Anti-inflammatory Drugs (NSAIDs)
- •Cyclooxygenase (COX) Inhibitors
- •Local Anesthetics
- •Opioid Analgesics—Morphine Type
- •General Anesthesia and General Anesthetic Drugs
- •Inhalational Anesthetics
- •Injectable Anesthetics
- •Sedatives, Hypnotics
- •Benzodiazepines
- •Pharmacokinetics of Benzodiazepines
- •Therapy of Depressive Illness
- •Mania
- •Therapy of Schizophrenia
- •Psychotomimetics (Psychedelics, Hallucinogens)
- •Hypothalamic and Hypophyseal Hormones
- •Thyroid Hormone Therapy
- •Glucocorticoid Therapy
- •Follicular Growth and Ovulation, Estrogen and Progestin Production
- •Oral Contraceptives
- •Antiestrogen and Antiprogestin Active Principles
- •Aromatase Inhibitors
- •Insulin Formulations
- •Treatment of Insulin-dependent Diabetes Mellitus
- •Treatment of Maturity-Onset (Type II) Diabetes Mellitus
- •Oral Antidiabetics
- •Drugs for Maintaining Calcium Homeostasis
- •Drugs for Treating Bacterial Infections
- •Inhibitors of Cell Wall Synthesis
- •Inhibitors of Tetrahydrofolate Synthesis
- •Inhibitors of DNA Function
- •Inhibitors of Protein Synthesis
- •Drugs for Treating Mycobacterial Infections
- •Drugs Used in the Treatment of Fungal Infections
- •Chemotherapy of Viral Infections
- •Drugs for the Treatment of AIDS
- •Drugs for Treating Endoparasitic and Ectoparasitic Infestations
- •Antimalarials
- •Other Tropical Diseases
- •Chemotherapy of Malignant Tumors
- •Targeting of Antineoplastic Drug Action (A)
- •Mechanisms of Resistance to Cytostatics (B)
- •Inhibition of Immune Responses
- •Antidotes and Treatment of Poisonings
- •Therapy of Selected Diseases
- •Hypertension
- •Angina Pectoris
- •Antianginal Drugs
- •Acute Coronary Syndrome— Myocardial Infarction
- •Congestive Heart Failure
- •Hypotension
- •Gout
- •Obesity—Sequelae and Therapeutic Approaches
- •Osteoporosis
- •Rheumatoid Arthritis
- •Migraine
- •Common Cold
- •Bronchial Asthma
- •Emesis
- •Alcohol Abuse
- •Local Treatment of Glaucoma
- •Further Reading
- •Further Reading
- •Picture Credits
- •Drug Indexes
Further Reading
Luellmann, Color Atlas of Pharmacology © 2005 Thieme
All rights reserved. Usage subject to terms and conditions of license.
350 Further Reading and Picture Credits
Further Reading
Foundations and Basic Principles of Pharmacology
Foreman JC, Johansen T. Textbook of Receptor Pharmacology. 2nd ed. New York: McGraw-Hill; 2002.
Hardman JG, Limbird LE, Gilman A. Goodman & Gilman’s The Pharmacological Basis of Therapeutics. 10th ed. New York: McGraw-Hill; 2001.
KatzungBG.BasicandClinicalPharmacology. 9th ed. New York: Lange Medical Books/ McGraw-Hill;2004.
Page CR, Curtis MJ, Sutter MC, Walker MJA, Hoffman BB. Integrated Pharmacology. 2nd ed. London: Mosby; 2002.
Pratt WB, Taylor P. Principles of Drug Ac- tion—The Basis of Pharmacology. 3rd ed. New York: Churchill Livingstone; 1990.
Rang HP, Dale MM, Ritter JM, Moore PK. Pharmacology. 5th ed. New York: Churchill Livingstone; 2003.
Clinical Pharmacology
Bennett PN, Brown MJ. Clinical Pharmacology. 9th ed. Edinburgh: Churchill Livingstone; 2003.
Caruthers SG, Hoffman BB, Melmon KL, Nierenberg DW. Melmon and Morelli’s Clinical Pharmacology—Basic Principles in Therapeutics. 4th ed. New York: McGraw-Hill; 2000.
Clinical Pharmacology—Electronic Drug Reference. Tampa, Florida: Gold Standard MultimediaInc.[Updatedevery4months].
Dipiro JT, Talbert RL, Yee GC, Matzke GR, Wells BG, Posey LM. Pharmacotherapy—A Pathophysiological Approach. New York: McGraw-Hill/Appleton and Lange; 2002.
Grahame-Smith D, Aronson J. Oxford Textbook of Clinical Pharmacology and Drug Therapy. 3rd ed. Oxford: Oxford University Press; 2002.
Drug Interactions and Adverse Effects
Davies DM, Ferner RE, de Glanville H. Davies’ Textbook of Adverse Drug Reactions. 5th ed. London: Chapman and Hall; 1998.
HanstenPD,HornJR.Druginteractions,Analysis and Management. Vancouver, WA: Applied Therapeutics Inc. [Updated every 4 months].
Websites
USA. FDA: www.fda.gov/medwatch/index.html UK. NHS: http://www.nhsdirect.nhs.uk/
Drugs in Pregnancy and Lactation
Briggs GG, Freeman RK, Yaffe SJ. Drugs in Pregnancy and Lactation: a Reference Guide to Fetal and Neonatal Risk. 6th ed. Baltimore: Williams and Wilkins; 2002.
Pharmacokinetics
Bauer LA. Applied Clinical Pharmacokinetics. New York: McGraw-Hill Med. Publ. Div.; 2001.
Boroujerdi M. Pharmacokinetics—Principles and Applications. New York: McGraw-Hill Med. Publ. Div.; 2002.
Shargel L, Yu A. Applied Biopharmaceutics and Pharmacokinetics. 4th ed. New York: McGraw-Hill Med. Publ. Div.; 1999.
Toxicology
Klaassen CD, Watkins J. Casarett and Doull’s Toxicology: The Basic Science of Poisons. 7th ed. New York: McGraw-Hill; 2003.
Picture Credits
p.75 Permission to use the two photographs in the plate on p.75 was kindly granted by Professor Enno Christophers, Head of the Department of Dermatology, Venereology
and Allergology at the University of Kiel.
p.297 A and B taken from: Lang W, Löschner T. Tropenmedizin in Klinik und Praxis. 3rd ed. Stuttgart: Thieme; 1999.
p.297 C taken from: Hof H, Dörries R. Medizinische Mikrobiologie. 2nd ed. Stuttgart: Thieme: 2002.
p.297 D taken from: Kayser F, Bienz KA, EckertJ,ZinkernagelRM.MedizinischeMikrobiologie.10th ed. Stuttgart: Thieme; 2001.
p.345 C taken from: Murken J, Clevett. Humangenetik. 6th ed. Stuttgart:Enke; 1996.
Luellmann, Color Atlas of Pharmacology © 2005 Thieme
All rights reserved. Usage subject to terms and conditions of license.